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Ageing Skeletal Muscle: The Ubiquitous Muscle Stem Cell
In 1999, in a review by Beardsley, the potential of adult stem cells, in repair and regeneration was heralded (Beardsley Sci Am 281:30–31, 1999)....
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Gli1 marks a sentinel muscle stem cell population for muscle regeneration
Adult skeletal muscle regeneration is mainly driven by muscle stem cells (MuSCs), which are highly heterogeneous. Although recent studies have...
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Autophagy in Muscle Stem Cells
Muscle stem cellsMuscle stem cell, also known as satellite cellsSatellite cell, are responsible for the regenerative capacity of adult muscle tissue...
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Insight into muscle stem cell regeneration and mechanobiology
Stem cells possess the unique ability to differentiate into specialized cell types. These specialized cell types can be used for regenerative...
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Muscle Progenitor Cell Fusion in the Maintenance of Skeletal Muscle
Skeletal muscle possesses a resident, multipotent stem cell population that is essential for its repair and maintenance throughout life. Here I...
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Regulation of muscle stem cell fate
Skeletal muscle plays a critical role in human health. Muscle stem cells (MuSCs) serve as the major cell type contributing to muscle regeneration by...
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Stem Cell Exhaustion
In a lifetime, several insults occur in human tissues and therefore, the regenerative and repair processes play a crucial role maintaining tissue...
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Extra Eyelid-Derived Muscle Stem Cells
Skeletal muscle stem cells (MuSCs) have been proposed as suitable candidates for cell therapy to muscular disorders since they exhibit a good...
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Mechanical compression creates a quiescent muscle stem cell niche
Tissue stem cell niches are regulated by their mechanical environment, notably the extracellular matrix (ECM). Skeletal muscles consist of bundled...
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Mini-MEndR: a miniaturized 96-well predictive assay to evaluate muscle stem cell-mediated repair
BackgroundFunctional evaluation of molecules that are predicted to promote stem cell mediated endogenous repair often requires in vivo transplant...
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Absence of the primary cilia formation gene Talpid3 impairs muscle stem cell function
Skeletal muscle stem cells (MuSC) are crucial for tissue homoeostasis and repair after injury. Following activation, they proliferate to generate...
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Visualizing MyoD Oscillations in Muscle Stem Cells
The bHLH transcription factor MyoD is a master regulator of myogenic differentiation, and its sustained expression in fibroblasts suffices to...
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Pax7 haploinsufficiency impairs muscle stem cell function in Cre-recombinase mice and underscores the importance of appropriate controls
Ever since its introduction as a genetic tool, the Cre-lox system has been widely used for molecular genetic studies in vivo in the context of health...
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Depletion of SAM leading to loss of heterochromatin drives muscle stem cell ageing
The global loss of heterochromatin during ageing has been observed in eukaryotes from yeast to humans, and this has been proposed as one of the...
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Quantification of Muscle Stem Cell Differentiation Using Live-Cell Imaging and Eccentricity Measures
Culturing primary muscle stem cellsMuscle stem cells ex vivo is a useful method for studying this cell population in controlled environments. Primary...
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Stem Cell Therapy After Neurological Injuries
Axonal degeneration, inflammation, neuronal death, and cytoarchitectural distortion can result from neurological injuries in both the central and...
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Terminated Ocular Stem Cell Studies
This chapter contains a listing and summary of all the terminated ocular stem cell studies. It covers terminated stem cell studies from the United...
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Application of Single-Cell Sequencing on Stem Cell Research
The variation and heterogeneity within cells are the fundamental features of stem cells. Each tissue has a resident stem cell niche compartmentalized...
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ATF3 induction prevents precocious activation of skeletal muscle stem cell by regulating H2B expression
Skeletal muscle stem cells (also called satellite cells, SCs) are important for maintaining muscle tissue homeostasis and damage-induced...
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Runx1+ vascular smooth muscle cells are essential for hematopoietic stem and progenitor cell development in vivo
Hematopoietic stem cells (HSCs) produce all essential cellular components of the blood. Stromal cell lines supporting HSCs follow a vascular smooth...
