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Macrophage migration inhibitory factor blockade reprograms macrophages and disrupts prosurvival signaling in acute myeloid leukemia
The malignant microenvironment plays a major role in the development of resistance to therapies and the occurrence of relapses in acute myeloid...
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Transcription factor 4 promotes increased corneal endothelial cellular migration by altering microtubules in Fuchs endothelial corneal dystrophy
Fuchs endothelial corneal dystrophy (FECD) is a complex corneal disease characterized by the progressive decline and morphological changes of corneal...
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Macrophage subsets and their role: co-relation with colony-stimulating factor-1 receptor and clinical relevance
Macrophages are one of the first innate immune cells to reach the site of infection or injury. Diverse functions from the uptake of pathogen or...
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Adiponectin affects the migration ability of bone marrow-derived mesenchymal stem cells via the regulation of hypoxia inducible factor 1α
BackgroundBone marrow (BM) is progressively filled with adipocytes during aging process. Thus, BM adipocytes-derived adiponectin (APN) affects the...
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Blockade of tumor-derived colony-stimulating factor 1 (CSF1) promotes an immune-permissive tumor microenvironment
The macrophage colony-stimulating factor 1 (CSF1) is a chemokine essential for the survival, proliferation, and differentiation of mononuclear...
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A case of acute lung injury in a peripheral blood stem cell donor mobilized with pegylated recombinant human granulocyte colony-stimulating factor
Pegylated recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF) has been introduced for the mobilization of peripheral blood stem...
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Increased thyroid stimulating hormone (TSH) as a possible risk factor for atherosclerosis in subclinical hypothyroidism
Primary hypothyroidism (PHT) is associated with an increased risk for the development of atherosclerosis (AS) and other cardiovascular disorders. PHT...
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MicroRNA-451 Regulates Angiogenesis in Intracerebral Hemorrhage by Targeting Macrophage Migration Inhibitory Factor
Intracerebral hemorrhage (ICH) is a subtype of stroke with the highest fatality and disability rate. Up to now, commonly used first-line therapies...
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Migration Stimulating Factor (MSF): Its Role in the Tumour Microenvironment
Migration Stimulating Factor (MSF) is a 70 kDa truncated isoform of fibronectin (FN); its mRNA is generated from the FN gene by an unusual two-stage... -
The relationship between sphingosine-1-phosphate receptor 2 and epidermal growth factor in migration and invasion of oral squamous cell carcinoma
Sphingosine-1-phosphate (S1P) is a lipid mediator and its binding to the S1P receptor 2 (S1PR2) is reported to regulate cytoskeletal organization....
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Synergistic Effect of Human Chorionic Gonadotropin and Granulocyte Colony Stimulating Factor in the Mobilization of HSPCs Improves Overall Survival After PBSCT in a Preclinical Murine Model. Are We Far Enough for Therapy?
Strategies to improve hematopoietic stem and progenitor cell (HSPC) mobilization from the bone marrow can have a pivotal role in addressing...
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The Effect of Granulocyte Colony-Stimulating Factor on Endometrial Receptivity of Implantation Failure Mouse
AbstractThe purpose of this study was to investigate the effect of G-CSF on the endometrial receptivity of implantation failure mice. Sixty female...
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A network map of macrophage-stimulating protein (MSP) signaling
Macrophage-stimulating protein (MSP), a serum-derived growth factor belonging to the plasminogen-related kringle domain family, is mainly produced by...
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Interleukin-6 and granulocyte colony-stimulating factor as predictors of the prognosis of influenza-associated pneumonia
BackgroundPneumonia is a common complication of influenza and closely related to mortality in influenza patients. The present study examines...
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Granulocyte-macrophage colony-stimulating factor suppresses induction of type I interferon in infants with severe pneumonia
BackgroundThe underlying mechanisms for infantile bronchopneumonia development remain unknown.
MethodsPeripheral blood mononuclear cell (PBMCs) and...
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Return Migration as a Factor of Sustainable Development in Border Regions of Russia
The specificity of return migration in Russia rests on historical backgrounds and since 2006 is in large part connected with the intentions of the... -
Skilled Migrants: Stimulating Knowledge Creation and Flows in Firms
This chapter examines the role of skilled migrants as an international business (IB) resource in stimulating knowledge creation in their country of... -
Exosomal NOX1 promotes tumor-associated macrophage M2 polarization-mediated cancer progression by stimulating ROS production in cervical cancer: a preliminary study
BackgroundCervical cancer the fourth most frequently diagnosed cancer and the fourth leading cause of cancer death in women, with an estimated...
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Regulatory role of Echinochrome A in cancer-associated fibroblast-mediated lung cancer cell migration
Echinochrome A (Ech A), a marine biosubstance isolated from sea urchins, is a strong antioxidant, and its clinical form, histochrome, is being used...
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Modulatory role of macrophage migration inhibitory factor on cytokines and clinical features of sarcoidosis
Sarcoidosis is a systemic granulomatous disease of unknown etiology with significant heterogeneity in organ manifestations and clinical course....