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Cytokinesis Blocked Micronuclei Aberration Analysis
Cytokinesis blocked micronuclei (CBMN) assay is a rapid and sensitive analysis of chromosome aberrations and miss assortments during cell division....
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Epigenetic dysregulation from chromosomal transit in micronuclei
Chromosomal instability (CIN) and epigenetic alterations are characteristics of advanced and metastatic cancers
1 –4 , but whether they are...
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Mitotic clustering of pulverized chromosomes from micronuclei
Complex genome rearrangements can be generated by the catastrophic pulverization of missegregated chromosomes trapped within micronuclei through a...
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The Composition of Micronuclei in T-Lymphocytes in Women Affected by Chronic Radiation Exposure
AbstractWe studied the chromosomal composition of micronuclei the peripheral blood T-lymphocytes of women chronically exposed due to their residence...
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Visualization of Fagopyrum esculentum and Fagopyrum tataricum Chromosomes and Micronuclei
This chapter presents the squash chromosome preparation technique for Fagopyrum esculentum and F. tataricum, using the root tips as the source of the...
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Fate of micronuclei and micronucleated cells after treatment of HeLa cells with different genotoxic agents
Although micronuclei are well-known biomarkers of genotoxic damage, the biological consequences of micronucleus induction are only poorly understood....
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Antecedent chromatin organization determines cGAS recruitment to ruptured micronuclei
Micronuclei (MN) are cytosolic bodies that sequester acentric fragments or mis-segregated chromosomes from the primary nucleus. Spontaneous rupture...
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A MATLAB-based program for three-dimensional quantitative analysis of micronuclei reveals that neuroinflammation induces micronuclei formation in the brain
The micronucleus is known to be a biomarker for genomic instability, which is a hallmark of tumors and aging. Normally, micronuclei are produced by...
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Micronuclei detection in oral cytologic smear: does it add diagnostic value?
BackgroundScreening and early diagnosis of oral squamous cell carcinoma (OSCC) are directly associated with increased survival rate and improved...
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Rapid and automatic detection of micronuclei in binucleated lymphocytes image
Cytokinesis block micronucleus (CBMN) assay is a widely used radiation biological dose estimation method. However, the subjectivity and the...
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Spontaneous activity of the mitochondrial apoptosis pathway drives chromosomal defects, the appearance of micronuclei and cancer metastasis through the Caspase-Activated DNAse
Micronuclei are DNA-containing structures separate from the nucleus found in cancer cells. Micronuclei are recognized by the immune sensor axis...
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Does cone-beam computed tomography examination increase the micronuclei frequency in the oral mucosa exfoliated cells? A systematic review and meta-analysis
ObjectiveThis systematic review (SR) with meta-analysis aimed to evaluate the frequency of micronuclei in the oral mucosa exfoliated cells after...
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Evaluation of micronuclei and antioxidant status in hospital radiation workers occupationally exposed to low-dose ionizing radiation
PurposeThere is scientific evidence that ionizing radiation (IR) can be responsible for various health hazards that are one of the concerns in...
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Redox Status, Immune Alterations, Histopathology, and Micronuclei Induction in Labeo rohita Dwelling in Polluted River Water
In this study, we measured various parameters of oxidative stress, immune response, and abnormalities in the erythrocyte nucleus of Labeo rohita ...
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ADAMTS1 Is Differentially Expressed in Human Lymphocytes with Various Frequencies of Endogenous γH2AX Foci and Radiation-Induced Micronuclei
AbstractThe level of spontaneous and radiation-induced DNA damage varies depending on genetic and environmental factors in human somatic cells. This...
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CDK4/6 inhibitor-induced bone marrow micronuclei might be caused by cell cycle arrest during erythropoiesis
BackgroundA micronucleus test is generally used to evaluate the genotoxic potential of chemicals. Exaggerated erythropoiesis, as occurs following...
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Eribulin induces micronuclei and enhances the nuclear localization of cGAS in triple-negative breast cancer cells
Eribulin (ERI), clinically utilized for locally advanced or metastatic breast tumors, has shown potential links to the immune system. Notably, the...
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Understanding the birth of rupture-prone and irreparable micronuclei
Micronuclei are extra-nuclear bodies mainly derived from ana-telophase lagging chromosomes/chromatins (LCs) that are not incorporated into primary...
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Potential use of distinct biomarkers (trace metals, micronuclei, and nuclear abnormalities) in a heterogeneous sample of birds in southern Brazil
The analysis of metal concentrations in bird feathers and genotoxicity tests are tools used to evaluate anthropogenic impacts on ecosystems. We...
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Reduced fertility caused by meiotic defects and micronuclei formation during microsporogenesis in xBrassicoraphanus
BackgroundHybridization and polyploidization events are important driving forces in plant evolution. Allopolyploids formed between different species...
