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miRNA Dysregulation in Schizophrenia
Schizophrenia is a complex neuropsychiatric disorder that alters synapse activity as well as neural circuits. An intricate intracellular network of... -
Quantum MiRNA Code
The C. elegans’s lin-4 discovery in 1993 to date are still limited to C. elegans-specific RNA interference. The function of microRNA (miRNA) is based... -
MiRNA Immunity Against Virus and MiRNA Surveillance Against Tumor
Through the microRNA (miRNA) entangling target sorting/quantum miRNA language plus artificial intelligence (METS/MIRAI) analysis so far, it seems... -
Oxford miRNA Gardener
Genetic traits are a curious question for biological research to elucidate the etiology of pathogenesis and are transmitted from cell to cell,... -
Programmed Evolution by miRNA Memory
Diseases are deeply implicated in the aberrant expression of microRNA (miRNA) genes. The RNA Wave 2000 dogma consists of four criteria, as first... -
A preliminary study of the miRNA restitution effect on CNV-induced miRNA downregulation in CAKUT
BackgroundThe majority of CAKUT-associated CNVs overlap at least one miRNA gene, thus affecting the cellular levels of the corresponding miRNA. We...
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Exosomal miRNA-146a and miRNA-424 as Possible Predictors of Immune Checkpoint Inhibitors Therapy Response in Clear Cell Renal Cell Carcinoma
AbstractClear cell renal cell carcinoma (ccRCC) is a malignant kidney tumour with a poor prognosis and difficult to treat. Despite significant...
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The significance of miRNA-191-5P and miRNA-24-3P as novel biomarkers for multiple sclerosis: a case–control study
BackgroundMultiple sclerosis (MS) is a long-term disease that can lead to disability. microRNAs (miRNA) can provide noninvasive markers allowing more...
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Experimental capture of miRNA targetomes: disease-specific 3′UTR library-based miRNA targetomics for Parkinson’s disease
The identification of targetomes remains a challenge given the pleiotropic effect of miRNAs, the limited effects of miRNAs on individual targets, and...
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Evaluation of Diagnostic Significance of Salivary miRNA-184 and miRNA-21 in Oral Squamous Cell Carcinoma and Oral Potentially Malignant Disorders
BackgroundAltered levels of miRNAs might affect the pathogenesis of oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders...
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Bioinformatics Analysis of miRNA Sequencing Data
The bioinformatics analysis of miRNA is a complicated task with multiple operations and steps involved from processing of raw sequence data to... -
Significance of MiRNA-34a and MiRNA-192 as a risk factor for nonalcoholic fatty liver disease
Background and aimsNAFLD is one of the fast-growing health problems that affects up to 25% of people worldwide. Numerous miRNAs have been clarified...
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Endogenous miRNA Sponges
MicroRNAs (miRNAs) are a class of noncoding RNAs of 17–22 nucleotides in length with a critical function in posttranscriptional gene regulation.... -
Almond miRNA Expression and Horticultural Implications
From the past, till now various improved almond cultivars with desired traits have been introduced through breeding programs based on classical and... -
Serum miRNA-21, miRNA-146a and plasma cell free DNA as novel biomarkers for assessing systemic lupus erythematosus activity
BackgroundMicroRNA and cell-free DNA have shown significant correlations with several autoimmune disorders including systemic lupus erythematosus...
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The spliceosome-associated protein CWC15 promotes miRNA biogenesis in Arabidopsis
MicroRNAs (miRNAs) play a key role in regulating gene expression and their biogenesis is precisely controlled through modulating the activity of...
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miRNA-7145-cuedc2 axis controls hematopoiesis through JAK1/STAT3 signaling pathway
Hematopoiesis ensures tissue oxygenation, and remodeling as well as immune protection in vertebrates. During embryogenesis, hemangioblasts are the...
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Preliminary study on miRNA in prostate cancer
ObjectiveTo screen for miRNAs differentially expressed in prostate cancer and prostate hyperplasia tissues and to validate their association with...
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miRNA Biogenesis and Regulation of Diseases: An Updated Overview
MicroRNAs (miRNAs) are small RNA molecules, with their role in gene silencing and translational repression by binding to the target mRNAs. Since it... -
MiRNA-202 Role in Reproductive System and Gynecological Cancers
IntroductionMicroRNAs, also known as miRNAs, are small regulatory RNAs, and they also include many different types in terms of size and commission...