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1. Neoadjuvant Therapy in Colon Cancer

   Neoadjuvant therapy in colon cancer, traditionally reserved for rectal cancer, is gaining traction as a promising treatment strategy. This chapter...

   Geerard L. Beets in Coloproctology

   Chapter 2024
   

2. BMAP-27 Peptide Reduces Proliferation and Increases Apoptosis in Primary and Metastatic Colon Cancer Cell Lines

   BMAP-27 peptide is reported to possess apoptotic and anti-proliferative effects against cancer cells but the actual mechanism of action is yet to be...

   Alakesh Das, Dikshita Deka, ... Surajit Pathak in International Journal of Peptide Research and Therapeutics

   Article Open access 19 October 2023
   

3. Arginase-1 inhibition reduces migration ability and metastatic colonization of colon cancer cells

   Background

   Arginase-1 (ARG1), a urea cycle-related enzyme, catalyzes the hydrolysis of arginine to urea and ornithine, which regulates the...

   **angdong Wang, Huihui **ang, ... Hidemitsu Kitamura in Cancer & Metabolism

   Article Open access 13 January 2023
   

4. Mechanism of bufalin inhibition of colon cancer liver metastasis by regulating M2-type polarization of Kupffer cells induced by highly metastatic colon cancer cells

   Patients with metastatic colorectal cancer often have poor outcomes, primarily due to hepatic metastasis. Colorectal cancer (CRC) cells have the...

   Donghao Tang, Hai**g Wang, ... **bao Chen in Apoptosis

   Article 23 February 2024
   

5. Prognostic impact and survival outcomes of colon perforation in patients with metastatic colorectal cancer: a multicenter retrospective cohort study

   Background

   Colon perforation caused by colorectal cancer (CRC) is a fatal condition requiring emergency intervention. For patients with metastatic...

   Eiichi Nakao, Hidetaka Kawamura, ... Shinichi Konno in International Journal of Clinical Oncology

   Article 11 December 2023
   

6. Case report: PRES associated with fruquintinib in a patient with metastatic colon cancer

   Posterior reversible encephalopathy syndrome (PRES) is a rare, reversible neurological disease that is frequently associated with the use of targeted...

   Lu Wang, Zhaohao Zeng, Zhiqiang Wu in Neurological Sciences

   Article Open access 15 August 2023
   

7. Conditional Overall Survival After Diagnosis of Non-Metastatic Colon Cancer: Impact of Laterality, MSI, and KRAS Status

   Background

   The prognostic relevance of laterality, microsatellite instability (MSI), and KRAS status in colon cancer has been established. However,...

   Catherine G. Tran, Paolo Goffredo, ... Imran Hassan in Annals of Surgical Oncology

   Article 19 October 2023
   

8. Synbiotics in Colon Cancer

   It’s no secret that cancer is a major cause of mortality in the globe. There are various types of cancer identified. Colon cancer (CCa) is the most...

   Hitesh Chopra, Rajat Goyal, ... Rupesh K. Gautam in Synbiotics for the Management of Cancer

   Chapter 2023
   

9. Overexpression of the NEK9–EG5 axis is a novel metastatic marker in pathologic stage T3 colon cancer

   NEK9 is a key player in the NEK9–EG5 axis for microtubule polymerization, chromosome alignment, and mitosis. In present study, we investigated the...

   Meejeong Kim, Hui Jeong Jeong, ... Jene Choi in Scientific Reports

   Article Open access 07 January 2023
   

10. Is Intensive Surveillance Necessary After Curative Resection for Colon Cancer?

    Surveillance after curative surgery for non-metastatic colon cancer is necessary, but the exact frequency and methods of that surveillance are still...

    Terrah J. Paul Olson in Difficult Decisions in Colorectal Surgery

    Chapter 2023
    

11. Antioxidant activities of thermally treated Sesamum indicum L. leaf extracts and their inhibitory effects against growth and metastatic properties of human colon cancer cells

    The study aimed to investigate antioxidant activities of two different thermally treated sesame ( Sesamum indicum L.) leaf ethanol extract, steamed...

    Seoyun Kim, Hwa ** Lee, Jihyeung Ju in Food Science and Biotechnology

    Article 23 September 2023
    

12. Functional proteomics of colon cancer Consensus Molecular Subtypes

    Background

    The Colorectal Cancer Subty** Consortium established four Consensus Molecular Subtypes (CMS) in colorectal cancer: CMS1...

    Jaime Feliu, Angelo Gámez-Pozo, ... Lucía Trilla-Fuertes in British Journal of Cancer

    Article 14 March 2024
    

13. Isolated Inguinal Lymph Node Metastasis from Colon Cancer: A Case Report

    Lymphatic spread of colon cancer usually occurs via mesenteric vessels (superior and inferior mesenteric vessels), but inguinal lymph node (LN)...

    Ahmed Motamiez, Ali Zedan, ... Ebrahim Aboeleuon in Indian Journal of Surgical Oncology

    Article 23 April 2024
    

14. Biomarkers in Colon Cancer Metastasis

    Globally, colorectal malignancies (CRC) continue to be one of the leading causes of cancer-related fatalities. Despite improvements in our...

    Prince Amoah Barnie, Daniel Boison, ... Su Zhaoliang in Handbook of Cancer and Immunology

    Living reference work entry 2023
    

15. Role of Block Copolymers in Colon Cancer

    Block copolymers are progressively being taken into consideration, particularly as carriers for the pharmacotherapy & management of different...

    Sumel Ashique, Ashish Garg, ... Vijay Sagar Madamsetty in Block Co-polymeric Nanocarriers: Design, Concept, and Therapeutic Applications

    Chapter 2023
    

16. Ascending colon cancer metastasized to the right testicle: a case report

    Background

    Testicular metastasis from malignant solid tumors is extremely rare. It is usually found by chance during autopsy or pathological...

    Qingqiang Gao, Yuanzhi Li, Leilei Zhu in Journal of Medical Case Reports

    Article Open access 27 June 2024
    

17. Extended procedure has no oncological benefits over segmental resection in the treatment of non-metastatic splenic flexure colon cancer, a population-based cohort study and a single center’s decade-long experience

    To compare the oncological survival outcome between extended resections (ER) and segmental resection (SR) for non-metastatic splenic flexure tumors....

    **aojie Wang, Yangyang Wang, ... Pan Chi in Updates in Surgery

    Article 31 May 2024
    

18. An Insight on Colon Cancer Stem Cells and Its Therapeutic Implications

    Colon cancer stem cells are a group of cells in a tumor that can reproduce themselves and change into different types of cells. They are thought to...

    Pournami Gopan S, Alakesh Das, ... Antara Banerjee in Handbook of Oncobiology: From Basic to Clinical Sciences

    Reference work entry 2024
    

19. Small Bowel and Colon Cancer

    Colorectal cancer represents the most common malignant neoplasm of the gastrointestinal (GI) tract; according to GLOBOCAN 2020, it represents the...

    Marta Zerunian, Gisella Guido, ... Andrea Laghi in Multimodality Imaging and Intervention in Oncology

    Chapter 2023
    

20. The survival impact of palliative chemotherapy dose modifications on metastatic colon cancer

    Background

    An uninterrupted dose of oxaliplatin-based cytotoxic therapy is an essential component in the standard treatment regimen of metastatic...

    Mohd Naqib Zainal Abidin, Marhanis Salihah Omar, ... Noraida Mohamed Shah in BMC Cancer

    Article Open access 04 July 2022