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Breast Cancer
Globally, breast cancer ranked first in incidence in the year 2020 with 22,61,419 new cases contributing to 11.7% of all cancers diagnosed and fifth...
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Metastatic Breast Cancer
Female/49 years old, post-menopause.
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Metastatic Breast Cancer: Diagnosis and Oncological Management
The vast majority of patients who are diagnosed with metastatic breast cancer (MBC) have relapsed after a primary diagnosis, and a complete...
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Breast Cancer
Breast cancer is a disease of aging, and most breast cancer cases and deaths worldwide occur among older adults. The last decades have brought an...
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Breast Cancer
Breast cancer is a disease of aging, and most breast cancer cases and deaths worldwide occur among older adults. The last decades have brought an...
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Breast Cancer Bone Metastases
Invasive breast carcinoma is the most common cancer diagnosed in the United States and the western world. The bone is the most common site of...
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A synthetic metastatic niche reveals antitumor neutrophils drive breast cancer metastatic dormancy in the lungs
Biomaterial scaffolds mimicking the environment in metastatic organs can deconstruct complex signals and facilitate the study of cancer progression...
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Breast Cancer
The appropriate selection of medical therapeutic interventions in breast cancer patients is a daily challenge for medical oncologists and takes into...
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Circulating tumor DNA validity and potential uses in metastatic breast cancer
Following the first characterization of circulating tumor DNA (ctDNA) in the 1990s, recent advances led to its introduction in the clinics. At...
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Metastatic Ovarian Cancer
Krukenberg tumours are rare metastatic signet ring cell ovarian tumour with primary in stomach, colorectal, appendiceal and breast carcinomas....
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Trastuzumab deruxtecan for human epidermal growth factor receptor 2-low advanced or metastatic breast cancer: recommendations from the Japanese Breast Cancer Society Clinical Practice Guidelines
The Japanese Breast Cancer Society Clinical Practice Guidelines are published as timely guidance on clinical issues in breast cancer treatment in...
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Metastatic Triple-Negative Breast Cancer
Purpose of ReviewTriple-negative breast cancer (TNBC) is a heterogeneous disease group with a known aggressive phenotype and poor prognosis. To date,...
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Genetic Testing in Metastatic Breast Cancer in the USA: A Podcast
This podcast highlights the importance of genetic testing in patients with metastatic breast cancer, with a specific focus on germline or inherited...
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De novo versus recurrent metastatic breast cancer affects the extent of brain metastases
PurposeWe aimed to identify factors associated with the extent of brain metastases in patients with breast cancer to help distinguish brain...
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Opposite and dynamic regulation of the interferon response in metastatic and non-metastatic breast cancer
BackgroundTo our current understanding, solid tumors depend on suppressed local immune reactions, often elicited by the interaction between tumor...
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Sacituzumab Govitecan: A Review in Unresectable or Metastatic HR+/HER2− Breast Cancer
Sacituzumab govitecan (TRODELVY ® ) is a first-in-class trophoblast cell-surface antigen 2 (Trop-2)–directed antibody and topoisomerase I inhibitor...
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Distinct shared and compartment-enriched oncogenic networks drive primary versus metastatic breast cancer
Metastatic breast-cancer is a major cause of death in women worldwide, yet the relationship between oncogenic drivers that promote metastatic versus...
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High percentage of Cancer Stem cells in metastatic locations: Upregulation of cicBIRC6 in highly metastatic breast Cancer Subline
BackgroundMetastasis is a devastating complication of breast cancer. Cancer relapse and metastasis are associated with cancer stem cells. CicBIRC6 is...
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Outcomes for breast cancer survivors with metastatic disease in a physical activity program for medically underserved cancer survivors
PurposeThis study examined the effectiveness and feasibility of the Active Living After Cancer (ALAC) program for metastatic breast cancer (MBC)...
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Recent Progress and Prospects of Immunotherapy in Multidrug-Resistant and Metastatic Breast Cancer Treatment
Although chemotherapy and mAbs are widely used in breast cancer treatment, these therapy approaches are allied with side effects and recurrence. US...