Search
Search Results
-
Natural killer cell-related gene signature predicts malignancy of glioma and the survival of patients
BackgroundNatural killer (NK) cells-based therapies are one of the most promising strategies against cancer. The aim of this study is to investigate...
-
Neural crest-related NXPH1/Ī±-NRXN signaling opposes neuroblastoma malignancy by inhibiting organotropic metastasis
Neuroblastoma is a pediatric cancer that can present as low- or high-risk tumors (LR-NBs and HR-NBs), the latter group showing poor prognosis due to...
-
Clinical implications of myeloid malignancyārelated somatic mutations in aplastic anemia
Aplastic anemia (AA) is a potentially fatal bone marrow failure syndrome characterized by a paucity of hematopoietic stem cells and progenitor cells...
-
Transcriptional and genetic alterations of cuproptosis-related genes correlated to malignancy and immune-infiltrate of esophageal carcinoma
Esophageal carcinoma (ESCA) is a common type of cancer with high mortality. Cuproptosis is a new type of cell death and is characterized by the...
-
Prognostic significance of CHCHD2P9 and ZNF204P in breast cancer: exploring their expression patterns and associations with malignancy-related genes
BackgroundNon-coding RNAs (ncRNAs) have a crucial impact on diverse cellular processes, influencing the progression of breast cancer (BC). The...
-
Negligible role of TRAIL death receptors in cell death upon endoplasmic reticulum stress in B-cell malignancies
Impairments in protein folding in the endoplasmic reticulum (ER) lead to a condition called ER stress, which can trigger apoptosis via the...
-
In-hospital prognosis of malignancy-related pulmonary embolism: an analysis of the national inpatient sample 2016ā2018
A substantial proportion of patients with malignancy develop pulmonary embolism (PE), which significantly worsens the prognosis and ranks as one of...
-
Establishment of a risk classifier to predict the in-hospital death risk of nosocomial fungal infections in cancer patients
BackgroundPatients with malignancy are at a higher risk of develo** nosocomial infections. However, limited studies investigated the clinical...
-
A novel TCGA-validated programmed cell-death-related signature of ovarian cancer
BackgroundOvarian cancer (OC) is a gynecological malignancy tumor with high recurrence and mortality rates. Programmed cell death (PCD) is an...
-
Combining multiple cell death pathway-related risk scores to develop neuroblastoma cell death signature
PurposeCell death plays an important role in tumourigenesis and progression; nevertheless, the clinical significance of cell death-related genes in...
-
Mortality rate and causes of death in papillary thyroid microcarcinoma
PurposePapillary thyroid microcarcinoma (PTMC) has an excellent prognosis; however, some PTMCs exhibit poor outcomes. Cancer-specific death from PTMC...
-
Creatinine-cystatin C ratio and death with a functioning graft in kidney transplant recipients
Death with a functioning graft is important cause of graft loss after kidney transplantation. However, little is known about factors predicting death...
-
Entosis: the core mechanism and crosstalk with other cell death programs
Cell death pathways play critical roles in organism development and homeostasis as well as in the pathogenesis of various diseases. While studies...
-
Causes of death after testicular cancer diagnosis: a US population-based analysis
BackgroundAfter the introduction of cisplatin-based chemotherapy, the survival time of testicular cancer (TC) patients has improved dramatically....
-
The broad impact of cell death genes on the human disease phenome
Cell death mediated by genetically defined signaling pathways influences the health and dynamics of all tissues, however the tissue specificity of...
-
Machine learning reveals diverse cell death patterns in lung adenocarcinoma prognosis and therapy
Cancer cell growth, metastasis, and drug resistance pose significant challenges in the management of lung adenocarcinoma (LUAD). However, there is a...
-
Frontier knowledge and future directions of programmed cell death in clear cell renal cell carcinoma
Clear cell renal cell carcinoma (ccRCC) is one of the most common renal malignancies of the urinary system. Patient outcomes are relatively poor due...
-
Cell death as an architect of adult skin stem cell niches
Our skin provides a physical and immunological barrier against dehydration and environmental insults ranging from microbial attacks, toxins and UV...
-
Regulated cell death pathways in kidney disease
Disorders of cell number that result from an imbalance between the death of parenchymal cells and the proliferation or recruitment of maladaptive...
-
Performance of postmortem CT in the diagnosis of natural death from out-of-hospital cardiac arrest
PurposePostmortem CT (PMCT) is used widely to identify the cause of death. However, its diagnostic performance in cases of natural death from...
