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1. Linkage Disequilibrium

   Amrita Mukhopadhyay in Encyclopedia of Sexual Psychology and Behavior

   Living reference work entry 2024
   

2. Linkage Disequilibrium Statistics and Block Visualization

   Linkage disequilibrium analysis enables researchers to interrogate the genome for patterns of coinheritance between genetic markers. Visualizing...

   Jacob Marsh in Plant Bioinformatics

   Protocol 2022
   

3. CoPheScan: phenome-wide association studies accounting for linkage disequilibrium

   Phenome-wide association studies (PheWAS) facilitate the discovery of associations between a single genetic variant with multiple phenotypes. For...

   Ichcha Manipur, Guillermo Reales, ... Chris Wallace in Nature Communications

   Article Open access 12 July 2024
   

4. Linkage Disequilibrium

   Linkage disequilibrium (LD) is the nonrandom association between alleles at closely linked loci. LD is created by genetic drift and natural...

   Montgomery Slatkin in Human Population Genomics

   Chapter 2021
   

5. Genomic prediction based on selective linkage disequilibrium pruning of low-coverage whole-genome sequence variants in a pure Duroc population

   Background

   Although the accumulation of whole-genome sequencing (WGS) data has accelerated the identification of mutations underlying complex traits,...

   Di Zhu, Yiqiang Zhao, ... **aoxiang Hu in Genetics Selection Evolution

   Article Open access 18 October 2023
   

6. Molecular genetic diversity and linkage disequilibrium structure of the Egyptian faba bean using Single Primer Enrichment Technology (SPET)

   Faba bean is an important legume crop. The genetic diversity among faba bean genotypes is very important for the genetic improvement of target...

   Ahmed Sallam, Ahmed Amro, ... Shamaseldeen Eltaher in BMC Genomics

   Article Open access 28 June 2024
   

7. Linkage Disequilibrium Score Statistic Regression for Identifying Novel Trait Associations

   Purpose of Review

   In this paper, we review the linkage disequilibrium score regression (LDSR) statistical method for computing correlation and shared...

   Rowland W. Pettit, Christopher I. Amos in Current Epidemiology Reports

   Article 24 June 2022
   

8. Genetic diversity, linkage disequilibrium, and population structure of tetraploid wheat landraces originating from Europe and Asia

   Background

   Durum wheat is one of the most important crops, especially in the Mediterranean region. Insight into the genetic diversity of germplasm can...

   Ehsan Rabieyan, Reza Darvishzadeh, ... Hadi Alipour in BMC Genomics

   Article Open access 14 November 2023
   

9. Genetic insights into crossbred dairy cattle of Pakistan: exploring allele frequency, linkage disequilibrium, and effective population size at a genome-wide scale

   Linkage disequilibrium (LD) affects genomic studies accuracy. High-density genoty** platforms identify SNPs across animal genomes, increasing LD...

   Fakhar un Nisa, Haiba Kaul, ... Zahid Mukhtar in Mammalian Genome

   Article 07 October 2023
   

10. Imputation of SNPs associated with presbycusis through linkage disequilibrium analysis in the ILDR1 gene

    The single-nucleotide polymorphisms (SNP) ILDR1 rs2332035 has shown a high statistical association with presbycusis (hearing loss with age or...

    Sergio V. Flores, Alejandro Levi-Monsalve, Juan Pablo Álvarez-Lobo in Journal of Genetics

    Article 10 January 2023
    

11. Linkage disequilibrium under polysomic inheritance

    Linkage disequilibrium (LD) is the non-random association of alleles at different loci. Squared LD coefficients r ² (for phased genotypes) and ...

    Kang Huang, Derek W. Dunn, ... Baoguo Li in Heredity

    Article 04 January 2022
    

12. Extremely sparse models of linkage disequilibrium in ancestrally diverse association studies

    Linkage disequilibrium (LD) is the correlation among nearby genetic variants. In genetic association studies, LD is often modeled using large...

    Pouria Salehi Nowbandegani, Anthony Wilder Wohns, ... Luke J. O’Connor in Nature Genetics

    Article 28 August 2023
    

13. Long-range linkage disequilibrium in French beef cattle breeds

    Background

    Linkage disequilibrium (LD) is a key parameter to study the history of populations and to identify and fine map quantitative trait loci...

    Abdelmajid El Hou, Dominique Rocha, ... Romain Philippe in Genetics Selection Evolution

    Article Open access 23 July 2021
    

14. Genome-wide diversity analysis to infer population structure and linkage disequilibrium among Colombian coconut germplasm

    Genetic diversity and relatedness of accessions for coconut growing in Colombia was unknown until this study. Here we develop single nucleotide...

    Jorge Mario Muñoz-Pérez, Gloria Patricia Cañas, ... Tatiana Arias in Scientific Reports

    Article Open access 22 February 2022
    

15. Molecular characterization of tall fescue germplasm using SNP markers: population structure, linkage disequilibrium, and association map** of yield-related traits

    Tall fescue ( Festuca arundinacea ) from Poaceae family is an allohexaploid (2 n =6 x =42) and cross pollinated plant that is used throughout the world as...

    Zeynab Shahabzadeh, Reza Darvishzadeh, ... Hadi Alipour in Plant Biotechnology Reports

    Article 14 June 2022
    

16. LDexpress: an online tool for integrating population-specific linkage disequilibrium patterns with tissue-specific expression data

    Genome-wide association studies have identified thousands of genetic susceptibility loci associated with cancer as well as other traits and diseases....

    Shu-Hong Lin, Rohit Thakur, Mitchell J. Machiela in BMC Bioinformatics

    Article Open access 20 December 2021
    

17. Impact of linkage disequilibrium heterogeneity along the genome on genomic prediction and heritability estimation

    Background

    Compared to medium-density single nucleotide polymorphism (SNP) data, high-density SNP data contain abundant genetic variants and provide...

    Duanyang Ren, **aodian Cai, ... Zhe Zhang in Genetics Selection Evolution

    Article Open access 27 June 2022
    

18. Estimation of cell-free fetal DNA fraction from maternal plasma based on linkage disequilibrium information

    Cell-free fetal DNA fraction (FF) in maternal plasma is a key parameter affecting the performance of noninvasive prenatal testing (NIPT). Accurate...

    Jia Ju, Jia Li, ... **n ** in npj Genomic Medicine

    Article Open access 12 October 2021
    

19. Patterns of genomic diversity and linkage disequilibrium across the disjunct range of the Australian forest tree Eucalyptus globulus

    The evolutionary trajectory of a population both influences and is influenced by characteristics of its genome. A disjunct population, for example is...

    Jakob B. Butler, Jules S. Freeman, ... Josquin F. G. Tibbits in Tree Genetics & Genomes

    Article Open access 02 June 2022
    

20. Significance of linkage disequilibrium and epistasis on genetic variances in noninbred and inbred populations

    Background

    The influence of linkage disequilibrium (LD), epistasis, and inbreeding on genotypic variance continues to be an important area of...

    José Marcelo Soriano Viana, Antonio Augusto Franco Garcia in BMC Genomics

    Article Open access 09 April 2022