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Social Determinants of Health and Limitation of Life-Sustaining Therapy in Neurocritical Care: A CHoRUS Pilot Project
BackgroundSocial determinants of health (SDOH) have been linked to neurocritical care outcomes. We sought to examine the extent to which SDOH explain...
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Prevalence, reasons, and timing of decisions to withhold/withdraw life-sustaining therapy for out-of-hospital cardiac arrest patients with extracorporeal cardiopulmonary resuscitation
BackgroundExtracorporeal cardiopulmonary resuscitation (ECPR) is rapidly becoming a common treatment strategy for patients with refractory cardiac...
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Limitation of life sustaining measures in neurocritical care: sex, timing, and advance directive
BackgroundThe limitation of life sustaining treatments (LLST) causes ethical dilemmas even in patients faced with poor prognosis, which applies to...
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Prinicples and Practice of Limiting Life-Sustaining Therapies
Decisions regarding the extent of treatment and the application of life-sustaining therapies in intensive care medicine maybe unambiguous at times:...
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Limiting life-sustaining treatment for very old ICU patients: cultural challenges and diverse practices
BackgroundDecisions about life-sustaining therapy (LST) in the intensive care unit (ICU) depend on predictions of survival as well as the expected...
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Limitation of Life-Sustaining Treatments
What are the limitations of life-sustaining treatment (LLST)?
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Life-Sustaining Therapies: Indication, Prognostication, and the Patient’s Wishes
Since treatment in an intensive care unit (ICU) can be burdensome and the outcome may be disappointing, the benefit and harm of an ICU treatment...
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Urban people’s preferences for life-sustaining treatment or artificial nutrition and hydration in advance decisions
BackgroundThe Patient Right to Autonomy Act (PRAA), implemented in Taiwan in 2019, enables the creation of advance decisions (AD) through advance...
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Declining to Provide or Continue Requested Life-Sustaining Treatment: Experience With a Hospital Resolving Conflict Policy
In 2015, the major critical care societies issued guidelines outlining a procedural approach to resolving intractable conflict between healthcare...
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Characteristics and outcomes of patients with do-not-resuscitate and physician orders for life-sustaining treatment in a medical intensive care unit: a retrospective cohort study
BackgroundIn the intensive care unit (ICU), we may encounter patients who have completed a Do-Not-Resuscitate (DNR) or a Physician Orders to Stop...
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Physicians’ attitudes and experiences about withholding/withdrawing life-sustaining treatments in pediatrics: a systematic review of quantitative evidence
BackgroundOne of the most important and ethically challenging decisions made for children with life-limiting conditions is withholding/withdrawing...
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Comparison of the end-of-life decisions of patients with hospital-acquired pneumonia after the enforcement of the life-sustaining treatment decision act in Korea
BackgroundAlthough the Life-Sustaining Treatment (LST) Decision Act was enforced in 2018 in Korea, data on whether it is well established in actual...
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Predictors and outcomes of withholding and withdrawal of life-sustaining treatments in intensive care units in Singapore: a multicentre observational study
BackgroundClinical practice guidelines on limitation of life-sustaining treatments (LST) in the intensive care unit (ICU), in the form of withholding...
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Eleven-year retrospective study characterizing patients with severe brain damage and poor neurological prognosis -role of physicians’ attitude toward life-sustaining treatment
BackgroundSevere brain hemorrhage/infarction and cardiac arrest constitute the most critical situations leading to poor neurological prognosis....
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Hospital to Hospital Transfers of Cerebral Hemorrhage: Characteristics of Early Withdrawal of Life-Sustaining Treatment
BackgroundLarge intracerebral hemorrhages (ICHs) are associated with significant morbidity and mortality. Patient transfer to higher level centers is...
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Clinical and molecular correlation defines activity of physiological pathways in life-sustaining kidney xenotransplantation
Porcine kidney xenotransplantation is accelerating towards clinical translation. However, despite the demonstrated ability of porcine kidneys to...
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Limitation of life-sustaining therapies in critically ill patients with COVID-19: a descriptive epidemiological investigation from the COVID-ICU study
BackgroundLimitations of life-sustaining therapies (LST) practices are frequent and vary among intensive care units (ICUs). However, scarce data were...
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Limitation of life-sustaining treatment and patient involvement in decision-making: a retrospective study of a Danish COVID-19 patient cohort
BackgroundThe coronavirus (COVID-19) pandemic and the risk of an extensive overload of the healthcare systems have elucidated the need to make...
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The role of clinical phenotypes in decisions to limit life-sustaining treatment for very old patients in the ICU
BackgroundLimiting life-sustaining treatment (LST) in the intensive care unit (ICU) by withholding or withdrawing interventional therapies is...
