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  1. Ischemia–Reperfusion Injury

    Ischemia has always been associated with immediate as well as delayed adverse consequences. Restoration of perfusion to ischemic tissues can also...
    Chandra Kant Pandey, S. S. Nath, Manish Tandon in Peri-operative Anesthetic Management in Liver Transplantation
    Chapter 2023
  2. Malonate given at reperfusion prevents post-myocardial infarction heart failure by decreasing ischemia/reperfusion injury

    The mitochondrial metabolite succinate is a key driver of ischemia/reperfusion injury (IRI). Targeting succinate metabolism by inhibiting succinate...

    Jiro Abe, Ana Vujic, ... Thomas Krieg in Basic Research in Cardiology
    Article Open access 12 June 2024
  3. Ischemia–Reperfusion Injury: Molecular Mechanisms of Pathogenesis and Methods of Their Correction

    Abstract —Ischemia–reperfusion is a cascade of complex and interrelated pathological processes underlying many human diseases, including such socially...

    R. G. Goncharov, M. G. Sharapov in Molecular Biology
    Article 07 December 2023
  4. The roles of intracellular proteolysis in cardiac ischemia–reperfusion injury

    Ischemic heart disease remains a leading cause of human mortality worldwide. One form of ischemic heart disease is ischemia–reperfusion injury caused...

    Bridgette Hartley, Wesam Bassiouni, ... Olivier Julien in Basic Research in Cardiology
    Article 28 September 2023
  5. Cardioprotective Strategies After Ischemia–Reperfusion Injury

    Acute myocardial infarction (AMI) is associated with high morbidity and mortality worldwide. Although early reperfusion is the most effective...

    Honghong Zhang, Huilin Hu, ... Hongen Tian in American Journal of Cardiovascular Drugs
    Article Open access 10 October 2023
  6. Advances in lung ischemia/reperfusion injury: unraveling the role of innate immunity

    Background

    Lung ischemia/reperfusion injury (LIRI) is a common occurrence in clinical practice and represents a significant complication following...

    Qingqing Li, Hanxiang Nie in Inflammation Research
    Article 24 January 2024
  7. The ability of microRNAs to regulate the immune response in ischemia/reperfusion inflammatory pathways

    MicroRNAs play a crucial role in regulating the immune responses induced by ischemia/reperfusion injury. Through their ability to modulate gene...

    Peter Artimovič, Ivana Špaková, ... Martina Zavacká in Genes & Immunity
    Article Open access 22 June 2024
  8. Deferoxamine attenuates visual impairment in retinal ischemia‒reperfusion via inhibiting ferroptosis

    Retinal ischemia‒reperfusion (I/R) injury can cause significant damage to human retinal neurons, greatly compromising their functions. Existing...

    **aoxuan Wang, Mingran Li, ... Minglian Zhang in Scientific Reports
    Article Open access 17 November 2023
  9. Ischemia-reperfusion injury: molecular mechanisms and therapeutic targets

    Ischemia-reperfusion (I/R) injury paradoxically occurs during reperfusion following ischemia, exacerbating the initial tissue damage. The limited...

    Meng Zhang, Qian Liu, ... **xiang Yuan in Signal Transduction and Targeted Therapy
    Article Open access 08 January 2024
  10. Conventional Method of Cardiac Ischemia/Reperfusion Injury in Mice

    Myocardial ischemia-reperfusion injury (IRI) after myocardial ischemia, cardiac surgery, or circulatory arrest leads to adverse cardiovascular...
    Sunghye Cho, Dongtak Jeong in Experimental Models of Cardiovascular Diseases
    Protocol 2024
  11. The effect of post-reperfusion levosimendan in an experimental intestinal ischemia–reperfusion model

    Background

    Levosimendan has been reported to have a positive effect on ischemia–reperfusion injury. Herein, we aimed to evaluate the effects of...

    Hakan Aygun, Cimen Olguner, ... Serkan Tulgar in Journal of Anesthesia, Analgesia and Critical Care
    Article Open access 27 October 2022
  12. Effect of miR-206 on lower limb ischemia–reperfusion injury in rat and its mechanism

    Lower limb ischemia–reperfusion is a common pathological process during clinical surgery. Because lower limb ischemia–reperfusion usually aggravates...

    Hui Wang, Meng-Jie Shi, ... Rui-Peng Zhang in Scientific Reports
    Article Open access 07 December 2023
  13. Mechanism of Reactive Oxygen/Nitrogen Species in Liver Ischemia-Reperfusion Injury and Preventive Effect of Chinese Medicine

    Liver ischemia-reperfusion injury (LIRI) is a pathological process involving multiple injury factors and cell types, with different stages....

    Lei Gao, Yun-jia Li, ... Jian-gang Shen in Chinese Journal of Integrative Medicine
    Article 28 June 2024
  14. Effect of 2-Week Naringin Supplementation on Neurogenesis and BDNF Levels in Ischemia–Reperfusion Model of Rats

    Background: Ischemic stroke is the leading cause of mortality and disability worldwide with more than half of survivors living with serious...

    Esen Yilmaz, Gozde Acar, ... Rasim Mogulkoc in NeuroMolecular Medicine
    Article Open access 08 March 2024
  15. Ferroptosis in organ ischemia–reperfusion injuries: recent advancements and strategies

    Ferroptosis is a newly discovered type of regulated cell death participated in multiple diseases. Different from other classical cell death programs...

    **aoyu Luan, Peng Chen, ... Guohu Di in Molecular and Cellular Biochemistry
    Article 31 March 2024
  16. The Protective Role of Transcript-Induced in Spermiogenesis 40 in Cerebral Ischemia–Reperfusion Injury

    Prompt reperfusion after cerebral ischemia is important to maintain neuronal survival and reduce permanent disability and death. However, the...

    **g **e, Lei Wang, ... Lang wang in Neurochemical Research
    Article 17 June 2024
  17. Ginsenoside Rg3 attenuates myocardial ischemia/reperfusion-induced ferroptosis via the keap1/Nrf2/GPX4 signaling pathway

    Background

    Ginsenoside Rg3 is a component of ginseng that protects against myocardial ischemia/reperfusion (MI/R) injury. Ferroptosis is a new form of...

    GuoFu Zhong, Junteng Chen, ... Ling Wang in BMC Complementary Medicine and Therapies
    Article Open access 26 June 2024
  18. Ferritinophagy and Ferroptosis in Cerebral Ischemia Reperfusion Injury

    Cerebral ischemia–reperfusion injury (CIRI) is the second leading cause of death worldwide, posing a huge risk to human life and health. Therefore,...

    **aoyue Liu, Canming **e, ... Haomei Tian in Neurochemical Research
    Article Open access 04 June 2024
  19. Identification of a mechanism promoting mitochondrial sterol accumulation during myocardial ischemia–reperfusion: role of TSPO and STAR

    Hypercholesterolemia is a major risk factor for coronary artery diseases and cardiac ischemic events. Cholesterol per se could also have negative...

    Juliette Bréhat, Shirin Leick, ... Didier Morin in Basic Research in Cardiology
    Article 22 March 2024
  20. MicroRNA-specific therapeutic targets and biomarkers of apoptosis following myocardial ischemia–reperfusion injury

    MicroRNAs are single-stranded non-coding RNAs that participate in post-transcriptional regulation of gene expression, it is involved in the...

    Teng Ge, Bo Ning, ... Mingjun Zhao in Molecular and Cellular Biochemistry
    Article 25 October 2023
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