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Embryo Models In Vitro Methods and Protocols
This collection explores the use of pluripotent cells to generate early embryo-like structures in vitro, with the resultant 3D embryo-like structures...
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Exploring Current In Vitro Models for Cancer Research
This chapter presents an extensive investigation into the diverse landscape of in vitro models tailored for unraveling the complexities of tumors....
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In Vitro Models and Proteomics in Osteoarthritis Research
This review summarizes and exemplifies the current understanding of osteoarthritis in vitro models and describes their relevance for new insights in...
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Precision nephrotoxicity testing using 3D in vitro models
Nephrotoxicity is a significant concern during the development of new drugs or when assessing the safety of chemicals in consumer products....
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Research Aspects and In Vitro Models
Since there is no adequate animal model for the investigation of human placental development, findings on cell biological processes of placental...
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In Vitro Models of Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis (ALS) is one of the commonest neurodegenerative diseases of adult-onset, which is characterized by the progressive...
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Models for calcific aortic valve disease in vivo and in vitro
Calcific Aortic Valve Disease (CAVD) is prevalent among the elderly as the most common valvular heart disease. Currently, no pharmaceutical...
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3D biofabrication of diseased human skin models in vitro
Human skin is an organ located in the outermost part of the body; thus, it frequently exhibits visible signs of physiological health. Ethical...
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Construction of in vitro liver-on-a-chip models and application progress
The liver is the largest internal organ of the human body. It has a complex structure and function and plays a vital role in drug metabolism. In...
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Embedded 3D Bioprinting for Engineering Miniaturized In Vitro Tumor Models
Embedded extrusion 3D bioprinting is a rapidly emerging additive manufacturing methodology that provides a precise spatial deposition of synthetic or...
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In vitro, ex vivo, and in vivo models for dental pulp regeneration
Based on the concept of tissue engineering (Cells—Scaffold—Bioactive molecules), regenerative endodontics appeared as a new notion for dental...
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In vitro and in vivo fermentation models to study the function of dietary fiber in pig nutrition
AbstractThe importance of dietary fiber (DF) in animal diets is increasing with the advancement of nutritional research. DF is fermented by gut...
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Review: Human stem cell-based 3D in vitro angiogenesis models for preclinical drug screening applications
Vascular diseases are the underlying pathology in many life-threatening illnesses. Human cellular and molecular mechanisms involved in angiogenesis...
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Diabetic retinopathy: a comprehensive update on in vivo, in vitro and ex vivo experimental models
Diabetic retinopathy (DR), one of the leading causes of visual impairment and blindness worldwide, is one of the major microvascular complications in...
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Newly developed 3D in vitro models to study tumor–immune interaction
Immunotherapy as a rapidly develo** therapeutic approach has revolutionized cancer treatment and revitalized the field of tumor immunology...
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Tumor Models of Retinoblastoma: In Vivo, Ex Vivo, and In Vitro Models
In the initial simplistic understanding, childhood retinal cancer retinoblastoma is due to the defect in the retinoblastoma gene. However, the deep...
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Develo** High-Fidelity In Vitro Models of Traumatic Brain Injury to Test Therapeutic Biomaterials
Introduction: Traumatic brain injury (TBI)Traumatic Brain Injury (TBI) can cause significant disability and is a leading cause of death amongst under...
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Prediction of cytochrome P450-mediated bioactivation using machine learning models and in vitro validation
Cytochrome P450 (P450)-mediated bioactivation, which can lead to the hepatotoxicity through the formation of reactive metabolites (RMs), has been...
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Single-cell transcriptome dataset of human and mouse in vitro adipogenesis models
Adipogenesis is a process in which fat-specific progenitor cells (preadipocytes) differentiate into adipocytes that carry out the key metabolic...
