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Kagami Ogata syndrome: a small deletion refines critical region for imprinting
Kagami–Ogata syndrome is a rare imprinting disorder and its phenotypic overlap with multiple different etiologies hampers diagnosis. Genetic...
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Balanced gene dosage control rather than parental origin underpins genomic imprinting
Mammalian parental imprinting represents an exquisite form of epigenetic control regulating the parent-specific monoallelic expression of genes in...
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Imprinting disorders
Imprinting disorders (ImpDis) are congenital conditions that are characterized by disturbances of genomic imprinting. The most common individual...
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Maintenance of methylation profile in imprinting control regions in human induced pluripotent stem cells
BackgroundParental imprinting is an epigenetic mechanism that leads to monoallelic expression of a subset of genes depending on their parental...
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Novel epigenetic molecular therapies for imprinting disorders
Genomic imprinting disorders are caused by the disruption of genomic imprinting processes leading to a deficit or increase of an active allele. Their...
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Genomic Imprinting and Random Monoallelic Expression
AbstractThe review discusses the mechanisms of monoallelic expression, such as genomic imprinting, in which gene transcription depends on the...
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Remote imprinting of moiré lattices
Two-dimensional moiré materials are formed by overlaying two layered crystals with small differences in orientation or/and lattice constant, where...
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G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions
Metazoan promoters are enriched in secondary DNA structure-forming motifs, such as G-quadruplexes (G4s). Here we describe ‘G4access’, an approach to...
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DNA sequence and chromatin modifiers cooperate to confer epigenetic bistability at imprinting control regions
Genomic imprinting is regulated by parental-specific DNA methylation of imprinting control regions (ICRs). Despite an identical DNA sequence, ICRs...
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Immune imprinting and next-generation coronavirus vaccines
Vaccines based on historical virus isolates provide limited protection from continuously evolving RNA viruses, such as influenza viruses or...
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Detection of DNA methylation signatures through the lens of genomic imprinting
Genomic imprinting represents an original model of epigenetic regulation resulting in a parent-of-origin expression. Despite the critical role of...
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Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting
The continuing emergence of SARS-CoV-2 variants highlights the need to update COVID-19 vaccine compositions. However, immune imprinting induced by...
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Imprinting of serum neutralizing antibodies by Wuhan-1 mRNA vaccines
Immune imprinting is a phenomenon in which prior antigenic experiences influence responses to subsequent infection or vaccination
1 ,2 . The effects of...
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Few-Shot Object Detection with Weight Imprinting
The goal of few-shot learning is to learn a solution to a problem from limited training samples. In recent years, with the promotion and application...
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Imprinting at the KBTBD6 locus involves species-specific maternal methylation and monoallelic expression in livestock animals
BackgroundThe primary differentially methylated regions (DMRs) which are maternally hypermethylated serve as imprinting control regions (ICRs) that...
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Along the Bos taurus genome, uncover candidate imprinting control regions
BackgroundIn mammals, Imprinting Control Regions (ICRs) regulate a subset of genes in a parent-of-origin-specific manner. In both human and mouse,...
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The mismatch-repair proteins MSH2 and MSH6 interact with the imprinting control regions through the ZFP57-KAP1 complex
BackgroundImprinting Control Regions (ICRs) are CpG-rich sequences acquiring differential methylation in the female and male germline and maintaining...
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Dental pulp stem cells as a promising model to study imprinting diseases
Parental imprinting is an epigenetic process leading to monoallelic expression of certain genes depending on their parental origin. Imprinting...
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Excess IPO funds as an imprint: An imprinting perspective of acquisition activity
This study focuses on the unique feature of Chinese firms’ excess funds raised from initial public offerings (IPOs) and examine why these funds have...
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Fabrication of high-performance lens arrays for micro-concentrator photovoltaics using ultraviolet imprinting
Micro-concentrator photovoltaics (micro-CPV) is a cutting-edge CPV approach aimed at increasing the efficiency and reducing the cost and carbon...
