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Hsp70 Knockdown in the Brine Shrimp Artemia franciscana: Implication on Reproduction, Immune Response and Embryonic Cuticular Structure
The potential functional role(s) of heat shock protein 70 (Hsp70) in the brine shrimp, Artemia franciscana , a crucial crustacean species for...
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Genome-Wide Identification and Characterization of the Hsp70/110 Genes in Two Polychaetes, Capitella teleta and Owenia fusiformis
AbstractHsp70/110s are a subfamily of heat shock proteins that play crucial roles against different types of environmental stressors and pathogenic...
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Insilico-based genome-wide identification and structural characterization of heat shock proteins 70 (HSP70) in cowpea (Vigna unguiculata L.)
Heat shock protein 70 is conserved a family of ubiquitously expressed proteins that help plants to withstand the major abiotic stresses. Although HSP70 ...
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Genome-wide identification and expression analysis of Hsp70 family genes in Cassava (Manihot esculenta Crantz)
Hsp70 proteins function as molecular chaperones, regulating various cellular processes in plants. In this study, a genome-wide analysis led to the...
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Differential expression and regulation of HSP70 gene during growth phase in ruminants in response to heat stress
Heat shock proteins regulate the physiological mechanism of heat stress adaptation at cellular level. The present investigation was carried out to...
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dTrmt10A impacts Hsp70 chaperone m6A levels and the stress response in the Drosophila brain
Chronic cellular stress has a profound impact on the brain, leading to degeneration and accelerated aging. Recent work has revealed the vital role of...
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A genome-wide screening of the 70 kDa heat shock protein (HSP70) genes in the rotifer Brachionus plicatilis sensu stricto with a characterization of two heat-inducible HSP70 genes
The 70 kDa heat shock proteins (HSP70s) and the constitutive members of the HSP70 family (heat shock cognates; HSC70s) play essential roles in...
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HSP70 upregulation in nasal mucosa of symptomatic children with allergic rhinitis and potential risk of asthma development
Allergic rhinitis and asthma are the most common causes of chronic inflammation of the upper and lower airways in childhood. However, a nasal...
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Structural remodeling of ribosome associated Hsp40-Hsp70 chaperones during co-translational folding
Ribosome associated complex (RAC), an obligate heterodimer of HSP40 and HSP70 (Zuo1 and Ssz1 in yeast), is conserved in eukaryotes and functions as...
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Can heat shock protein 70 (HSP70) serve as biomarkers in Antarctica for future ocean acidification, warming and salinity stress?
The Antarctic Peninsula is one of the fastest-warming places on Earth. Elevated sea water temperatures cause glacier and sea ice melting. When...
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Differentially expressed transcripts of Tetracapsuloides bryosalmonae (Cnidaria) between carrier and dead-end hosts involved in key biological processes: novel insights from a coupled approach of FACS and RNA sequencing
Tetracapsuloides bryosalmonae is a malacosporean endoparasite that infects a wide range of salmonids and causes proliferative kidney disease (PKD)....
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Transcriptome analysis of cervical cancer exosomes and detection of HPVE6*I transcripts in exosomal RNA
BackgroundExosomes play a key role in cell-to-cell communication and are integral component of the tumor microenvironment. Recent observations...
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Integrated RNA-seq and RNAi Analysis of the Roles of the Hsp70 and SP Genes in Red-Shell Meretrix meretrix Tolerance to the Pathogen Vibrio parahaemolyticus
The “Wanlihong” Meretrix meretrix (WLH-M) clam is a new variety of this species that has a red shell and stronger Vibrio tolerance than ordinary M....
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Systematic analysis of Heat Shock Protein 70 (HSP70) gene family in radish and potential roles in stress tolerance
The 70 kD heat shock proteins (HSP70s) represent a class of molecular chaperones that are widely distributed in all kingdoms of life, which play...
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Cryostress induces fragmentation and alters the abundance of sperm transcripts associated with fertilizing competence and reproductive processes in buffalo
The study aimed to assess the influence of cryostress on RNA integrity and functional significance in sperm fertilizing ability. The fresh and...
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Caspase-mediated cleavage of miRNA processing proteins Drosha, DGCR8, Dicer, and TRBP2 in heat-shocked cells and its inhibition by HSP70 overexpression
Cells respond to stress through adaptive mechanisms that limit cellular damage and prevent cell death. MicroRNAs act as regulators of stress...
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Small-molecule inhibitor targeting the Hsp70-Bim protein–protein interaction in CML cells overcomes BCR-ABL-independent TKI resistance
Herein, we screened a novel inhibitor of the Hsp70-Bim protein-protein interaction (PPI), S1g-2 , from a Bcl-2 inhibitor library; this compound...
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Alternative splicing of the SUMO1/2/3 transcripts affects cellular SUMOylation and produces functionally distinct SUMO protein isoforms
Substantial increases in the conjugation of the main human SUMO paralogs, SUMO1, SUMO2, and SUMO3, are observed upon exposure to different cellular...
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Molecular cloning, expression HSP70 and its response to bacterial challenge and heat stress in Microptenus salmoides
The gene encoding HSP70 was isolated from Microptenus salmoides by homologous cloning and rapid amplification of cDNA ends (RACE). The HSP70...
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Muscle Transcriptome Sequencing Revealed Thermal Stress–Responsive Regulatory Genes in Farmed Rohu, Labeo rohita (Hamilton, 1822)
Rohu, Labeo rohita , is one of the most important aquaculture species in the Indian subcontinent. Understanding the molecular-level physiological...
