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Growth Factor Therapy
Many of chronic wounds are delayed or fail to heal through conventional treatment because attenuated activities of cells responsible for wound...
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Insulin-like growth factor signalling
This Collection welcomes original research on all aspects of insulin-like growth factor signalling, from structural chemistry through cell biology...
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Insulin-like growth factor-1 and insulin-like growth factor binding protein-3 as early predictors of growth, body composition, and neurodevelopment in preterm infants
ObjectiveTo investigate the relationship between insulin-like growth factor 1 (IGF-1), insulin-like growth factor binding protein 3 (IGFBP-3) and...
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The Opioid Growth Factor in Growth Regulation and Immune Responses in Cancer
It has become apparent that endogenous opioids act not only as neurotransmitters and neuromodulators, but have multiple functions in the body....
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Harnessing Growth Factor Interactions to Optimize Articular Cartilage Repair
The failure of cartilage healingHealing is a major impediment to recovery from jointJoint diseaseDisease or trauma. Growth factors play a central...
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Expression of Vascular Endothelial Growth Factor at High Altitude
Oxygen plays an important role in aerobic respiration in mammals. However, there is subsequent decrease in partial pressure of oxygen with increase...
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Are Altered Expression of Vascular Endothelial Growth Factor and Placental Growth Factor Associated with Placental Angiogenesis in Recurrent Pregnancy Loss?
Angiogenesis is one of the most important steps during pregnancy for placental and fetal development. Based on the hypothesis that vascular...
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Analysis of serum insulin-like growth factor-1, fibroblast growth factor 23, and Klotho levels in girls with rapidly progressive central precocious puberty
To study the levels of serum insulin-like growth factor 1 (IGF-1), fibroblast growth factor 23 (FGF23), and Klotho, and to study their relationship...
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Identification of myeloid-derived growth factor as a mechanically-induced, growth-promoting angiocrine signal for human hepatocytes
Recently, we have shown that after partial hepatectomy (PHx), an increased hepatic blood flow initiates liver growth in mice by vasodilation and...
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Perinatal Insulin-Like Growth Factor as a Risk Factor for Autism
As early as 1988, insulin-like growth factor-1 (IGF1) and truncated IGF1 were identified in bovine colostrum. Subsequent studies, to be reviewed...
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Brain-Derived Neurotrophic Factor and Vascular Endothelial Growth Factor A: Biomarkers Potential in Diabetes
Previously, brain-derived neurotrophic factor (BDNF) and vascular endothelial growth factor (VEGF) have been studied only in diabetic neuropathy or...
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Nuclear factor-κB activation by transforming growth factor-β1 drives tumour microenvironment-mediated drug resistance in neuroblastoma
BackgroundIntrinsic and extrinsic factors in the tumour microenvironment (TME) contribute to therapeutic resistance. Here we demonstrate that...
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Epidermal Growth Factor (EGF) in Wound Repair
Growth factors are vital for regulating many of our cellular processes. Growth factors classically act as signalling...
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Posterior vitreous attachment as a risk factor for endophthalmitis following intravitreal antivascular endothelial growth factor injection
PurposeTo evaluate the importance of the status of posterior vitreous in eyes with endophthalmitis following intravitreal anti-vascular endothelial...
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The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer
PurposeThe gastric adenocarcinoma (GC) represents the third cause of cancer-related mortality worldwide, and available therapeutic options remain...
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Plumbagin binds to epidermal growth factor receptor and mitigate the effects of epidermal growth factor micro-environment in PANC-1 cells
A sustained increase in the mortality of pancreatic cancer (PC) and sudden metastasis-related mortality is a cause for concern. Aberrant expression...
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NUAK1 coordinates growth factor-dependent activation of mTORC2 and Akt signaling
BackgroundmTORC2 is a critical regulator of cytoskeleton organization, cell proliferation, and cancer cell survival. Activated mTORC2 induces maximal...
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Imprinted Grb10, encoding growth factor receptor bound protein 10, regulates fetal growth independently of the insulin-like growth factor type 1 receptor (Igf1r) and insulin receptor (Insr) genes
BackgroundOptimal size at birth dictates perinatal survival and long-term risk of develo** common disorders such as obesity, type 2 diabetes and...
