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  1. Gene Delivery

    Gene therapy has been regarded as a great potential for specific treatment of gene-related human diseases, such as cancer, genetic and epidemic...
    Huayu Tian, Xuesi Chen in Biomaterial Engineering
    Book 2022
  2. Gene Delivery Using Polymer Therapeutics

    The use of polymers as synthetic non-viral carriers for introducing nucleic acids into cells appears very appealing. Polymers can be generated in...
    Ernst Wagner, Julia Kloeckner in Polymer Therapeutics I
    Chapter
  3. Materials for Gene Delivery Systems

    Gene therapy has garnered a lot of interest in the recent past for the treatment of various life-threatening genetic diseases. Gene therapy involves...
    S. K. Manohar, M. P. Gowrav, H. V. Gangadharappa in Interaction of Nanomaterials With Living Cells
    Chapter 2023
  4. Gene Delivery to Chondrocytes

    Delivering genes to chondrocytes offers new possibilities both clinically, for treating conditions that affect cartilage, and in the...
    Christopher V. Nagelli, Christopher H. Evans, Rodolfo E. De la Vega in Electromechanobiology of Cartilage and Osteoarthritis
    Chapter Open access 2023
  5. Microfluidic Approaches for Gene Delivery and Therapy

    Gene editing techniques such as Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR/Cas9) have been developed to target a gene into...
    Mayur Parekh, Zulfiqur Ali in Microfluidics in Pharmaceutical Sciences
    Chapter 2024
  6. Alginate in Gene and Vaccine Delivery

    Gene and vaccine delivery offer promising technologies for the treatment of several diseases. However, they suffer from low transfection efficacy,...
    Hani Nasser Abdelhamid in Alginate Biomaterial
    Chapter 2023
  7. Simple Magnetic Nanoparticle-Based System for Gene Delivery

    Due to their unique properties such as superparamagnetism, biocompatibility and bio-friendly, magnetic nanoparticles (MNPs) have been successfully...
    Tuan Huy Pham, Duc Minh Huy Nguyen, ... Thi Hai Yen Tran in 9th International Conference on the Development of Biomedical Engineering in Vietnam
    Conference paper 2024
  8. Gene Therapy in Molecular Biology and Drug Delivery

    The objective of gene therapy is to manipulate/modify the gene expression or modify living cell characteristics for therapeutic utilization. It aims...
    Chapter 2024
  9. Engineering viral vectors for acoustically targeted gene delivery

    Targeted gene delivery to the brain is a critical tool for neuroscience research and has significant potential to treat human disease. However, the...

    Hongyi R. Li, Manwal Harb, ... Jerzy O. Szablowski in Nature Communications
    Article Open access 10 June 2024
  10. Recent progress of iron-based nanomaterials in gene delivery and tumor gene therapy

    Gene therapy aims to modify or manipulate gene expression and change the biological characteristics of living cells to achieve the purpose of...

    Ya Gong, **aoyan Hu, ... Jun Wang in Journal of Nanobiotechnology
    Article Open access 02 June 2024
  11. Targeted gene delivery systems for T-cell engineering

    T lymphocytes are indispensable for the host systems of defense against pathogens, tumors, and environmental threats. The therapeutic potential of...

    Fengling Wang, Yong Huang, ... Wei Wang in Cellular Oncology
    Article 16 May 2024
  12. Gene therapy for CNS disorders: modalities, delivery and translational challenges

    Gene therapy is emerging as a powerful tool to modulate abnormal gene expression, a hallmark of most CNS disorders. The transformative potentials of...

    **g**g Gao, Swetharajan Gunasekar, ... Nitin Joshi in Nature Reviews Neuroscience
    Article 19 June 2024
  13. Biomaterials in Gene Delivery

    The creation of biomaterials and their advancements is not a new thing in the field of research and science. Biomaterials science is a stimulating...
    Muhammad Usama Saeed, Nazim Hussain, Muhammad Bilal in Functional Biomaterials
    Chapter 2022
  14. Emerging non-viral vectors for gene delivery

    Gene therapy holds great promise for treating a multitude of inherited and acquired diseases by delivering functional genes, comprising DNA or RNA,...

    Chenfei Wang, Chaolan Pan, ... Ming Li in Journal of Nanobiotechnology
    Article Open access 17 August 2023
  15. ZIF-8 Nanoparticle: A Valuable Tool for Improving Gene Delivery in Sperm-Mediated Gene Transfer

    Metal–organic frameworks (MOFs) are porous materials with unique characteristics that make them well-suited for drug delivery and gene therapy...

    Marzieh Sameni, Parisa Moradbeigi, ... Mohammad Salehi in Biological Procedures Online
    Article Open access 26 January 2024
  16. Viral Gene Delivery in Chondrocytes

    Viral gene transfer, known as transduction, is a powerful research tool for studying the biology of chondrocytes in novel ways and also a technology...
    Christopher V. Nagelli, Christopher H. Evans, Rodolfo E. De La Vega in Cartilage Tissue Engineering
    Protocol 2023
  17. Recent advances in gene delivery nanoplatforms based on spherical nucleic acids

    Gene therapy is a therapeutic option for mitigating diseases that do not respond well to pharmacological therapy. This type of therapy allows for...

    Nazila Valatabar, Fatemeh Oroojalian, ... Amirhossein Sahebkar in Journal of Nanobiotechnology
    Article Open access 01 July 2024
  18. Maternal Gene Delivery for the Prevention and Treatment of Obstetric Conditions

    Purpose of Review

    There is an urgent unmet clinical need for effective therapies for obstetric complications such as fetal growth restriction,...

    Sophia C. D’Alessandro, Ashley K. Boyle in Current Stem Cell Reports
    Article Open access 06 June 2024
  19. Efficient and scalable gene delivery method with easily generated cationic carbon dots

    Gene delivery is a complex process with several challenges when attempting to incorporate genetic material efficiently and safely into target cells....

    Manuel Algarra, Elena Gonzalez-Muñoz in Biological Procedures Online
    Article Open access 08 March 2024
  20. New Avenues of Delivery (Subretinal Gene Therapy, Port Delivery, Suprachoroidal)

    Ocular drug delivery provides many unique challenges due to the ocular blood–brain barrier. In general, ocular drug delivery can be split into...
    Archana A. Nair, Siyang Chaili, Janice C. Law in Current Advances in Ocular Surgery
    Chapter 2023
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