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Gene–Nutrient Interaction and Cancer Prevention
Research on carcinogenesis has provided a plethora of knowledge regarding cancer. Cancer cells are the product of numerous genetic abnormalities that...
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Association of obesity and menarche SNPs and interaction with environmental factors on precocious puberty
BackgroundObesity is an important cause for the precocious or early puberty. However, the association between obesity-related loci and the risk of...
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Gene–Nutrient Interaction and Cancer Prevention
Research on carcinogenesis has provided a plethora of knowledge regarding cancer. Cancer cells are the product of numerous genetic abnormalities that...
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Microplastic pollution interaction with disinfectant resistance genes: research progress, environmental impacts, and potential threats
The consumption of disposable plastic products and disinfectants has surged during the global COVID-19 pandemic, as they play a vital role in...
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Gene-environment interaction analysis of school quality and educational inequality
We study to what extent schools increase or decrease environmental and genetic influences on educational performance. Building on behavioral genetics...
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The airway microbiome mediates the interaction between environmental exposure and respiratory health in humans
Exposure to environmental pollution influences respiratory health. The role of the airway microbial ecosystem underlying the interaction of exposure...
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Interaction between childhood trauma experience and TPH2 rs7305115 gene polymorphism in brain gray matter volume
BackgroundChildhood trauma is one of the most extensively studied and well-supported environmental risk factors for the development of mental health...
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Influence of arsenic exposure and TGF-β gene single nucleotide polymorphisms (gene-environment interaction) on cardiovascular risk biomarkers levels in Mexican people from San Luis Potosi, Mexico
ObjectiveCardiovascular diseases (CVD) are the primary cause of death worldwide. Therefore, this investigation aimed to evaluate the effect of...
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A Varying Coefficient Model to Jointly Test Genetic and Gene–Environment Interaction Effects
Most human traits are influenced by the interplay between genetic and environmental factors. Many statistical methods have been proposed to screen...
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The effect of environmental variables on the genoty**-by-environment interaction in blueberry
Blueberry ( Vaccinium corymbosum ) has an important role in the global market, with consumption increasing steadily in the past decades. Adapted to...
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A versatile, fast and unbiased method for estimation of gene-by-environment interaction effects on biobank-scale datasets
Identification of gene-by-environment interactions (GxE) is crucial to understand the interplay of environmental effects on complex traits. However,...
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A Longitudinal Analysis of Gene x Environment Interaction on Verbal Intelligence Across Adolescence and Early Adulthood
The Scarr-Rowe hypothesis proposes that the heritability of intelligence is higher in more advantaged socioeconomic contexts. An early demonstration...
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Probing the diabetes and colorectal cancer relationship using gene – environment interaction analyses
BackgroundDiabetes is an established risk factor for colorectal cancer. However, the mechanisms underlying this relationship still require...
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Epigenetics and environmental health
Epigenetic modifications including DNA methylation, histone modifications, chromatin remodeling, and RNA modifications complicate gene regulation and...
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Grapevine scion gene expression is driven by rootstock and environment interaction
BackgroundGrafting is a horticultural practice used widely across woody perennial crop species to fuse together the root and shoot system of two...
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Weak gene–gene interaction facilitates the evolution of gene expression plasticity
BackgroundIndividual organisms may exhibit phenotypic plasticity when they acclimate to different conditions. Such plastic responses may facilitate...
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Evolution of lysine-specific demethylase 1 and REST corepressor gene families and their molecular interaction
Lysine-specific demethylase 1A (LSD1) binds to the REST corepressor (RCOR) protein family of corepressors to erase transcriptionally active marks on...
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Microbial diversity and ecological complexity emerging from environmental variation and horizontal gene transfer in a simple mathematical model
BackgroundMicrobiomes are generally characterized by high diversity of coexisting microbial species and strains, and microbiome composition typically...
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Gene-by-Environment Interaction Effects of Social Adversity on Externalizing Behavior in ABCD Youth
This study tested whether multiple domains of social adversity, including neighborhood opportunity/deprivation and life stress, moderate genetic ( A ),...
