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Flux Balance Analysis of Mammalian Cell Systems
Flux balance analysis (FBA) is a computational methodology to model and analyze the metabolic behavior of cells. In this chapter, we break down the...
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‘Social’ versus ‘asocial’ cells—dynamic competition flux balance analysis
In multicellular organisms cells compete for resources or growth factors. If any one cell type wins, the co-existence of diverse cell types...
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Integration of Metabolomics and Flux Balance Analysis: Applications and Challenges
This book chapter presents an in-depth analysis of the integration of metabolomics and flux balance analysis (FBA) as powerful tools for...
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Discretised Flux Balance Analysis for Reaction–Diffusion Simulation of Single-Cell Metabolism
Metabolites have to diffuse within the sub-cellular compartments they occupy to specific locations where enzymes are, so reactions could occur....
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Predicting microbial interactions with approaches based on flux balance analysis: an evaluation
BackgroundGiven a genome-scale metabolic model (GEM) of a microorganism and criteria for optimization, flux balance analysis (FBA) predicts the...
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A dynamic model of growth phase of bio-conversion of methane to polyhydroxybutyrate using dynamic flux balance analysis
Biological conversion of waste methane to biodegradable plastics is a way of reducing their production cost. This study addresses the computational...
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scFBApy: A Python Framework for Super-Network Flux Balance Analysis
Constraint-based modelling (CBM) is a computational method used in systems biology to predict metabolic fluxes. However, modelling metabolic fluxes...
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Genome-scale modeling of Chinese hamster ovary cells by hybrid semi-parametric flux balance analysis
Flux balance analysis (FBA) is currently the standard method to compute metabolic fluxes in genome-scale networks. Several FBA extensions employing...
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Combining denoising of RNA-seq data and flux balance analysis for cluster analysis of single cells
BackgroundSophisticated methods to properly pre-process and analyze the increasing collection of single-cell RNA sequencing (scRNA-seq) data are...
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Advection surface-flux balance controls the seasonal steric sea level amplitude
Along with the mean sea level rise due to climate change, the sea level exhibits natural variations at a large number of different time scales. One...
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Fluxomics and Metabolic Flux Analysis
Fluxomics and metabolic flux analysis (MFA) are cutting-edge experimental techniques in a biological system focuses on quantifying the flux of...
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From Stationary to Instationary Metabolic Flux Analysis
Metabolic flux analysis using 13C labeled substrates is an important tool for metabolic engineering. Although it has now been evolving for more than...
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Integrating metagenomic binning with flux balance analysis to unravel syntrophies in anaerobic CO2 methanation
BackgroundCarbon fixation through biological methanation has emerged as a promising technology to produce renewable energy in the context of the...
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Trajectory attractors of energy balance climate models with bio-feedback and latent energy flux
The class of energy balance models under consideration accounts for the change of the latent energy flux due to melting (ice-sheets, permafrost) and...
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Metabolic flux analysis and metabolic engineering for polyhydroxybutyrate (PHB) production
Metabolic engineering provides a more sustainable alternative by using complex metabolic processes to generate valuable compounds by exploiting...
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Flux-Weakening Control
Flux-weakening is essential for high speed electric machine control. Various flux-weakening approaches are analyzed and discussed in this chapter....
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Balance Equations
Borrowing from the mechanics of systems of particles, the balance equations for mass, linear momentum, and angular momentum are established. Next,...
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Analysis of flux footprints in fragmented, heterogeneous croplands
An accurate quantification of fluxes from heterogeneous sites and further bifurcation into contributing homogeneous fluxes is an active field of...
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Unveiling evapotranspiration patterns and energy balance in a subalpine forest of the Qinghai–Tibet Plateau: observations and analysis from an eddy covariance system
Evapotranspiration is an important parameter used to characterize the water cycle of ecosystems. To understand the properties of the...
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An improved algorithm for flux variability analysis
Flux balance analysis (FBA) is an optimization based approach to find the optimal steady state of a metabolic network, commonly of microorganisms...
