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Identification of Electron Transfer in the System of Ferredoxins and Ferredoxin Reductases from Mycolicibacterium smegmatis
AbstractSteroid-26-monooxygenases belong to the cytochrome P450 superfamily and function as part of three-component systems together with ferredoxins...
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Redox State of Photosynthetic Ferredoxin Under Heat and Light Stress
The kinetics of oxidation/reduction of the primary donor of photosystem 1 (PS1) P700, plastocyanin (PC), and ferredoxin (Fd) in the first leaves of...
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Ferredoxin 1: a gatekeeper in halting lung adenocarcinoma progression through activation of the GPRIN2 signaling pathway
BackgroundLung adenocarcinoma (LUAD) is a highly lethal form of lung cancer. Despite advancements in treatments, managing LUAD is still challenging...
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Overexpressing plant ferredoxin-like protein enhances photosynthetic efficiency and carbohydrates accumulation in Phalaenopsis
Crassulacean acid metabolism (CAM) is one of three major models of carbon dioxide assimilation pathway with better water-use efficiency and slower...
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EPR studies of ferredoxin in spinach and cyanobacterial thylakoids related to photosystem I-driven NADP+ reduction
Photosynthetic light-dependent reactions occur in thylakoid membranes where embedded proteins capture light energy and convert it to chemical energy...
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Structure of cyanobacterial photosystem I complexed with ferredoxin at 1.97 Å resolution
Photosystem I (PSI) is a light driven electron pump transferring electrons from Cytochrome c 6 (Cyt c 6 ) to Ferredoxin (Fd). An understanding of this...
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Genome sequencing of cucumber mosaic virus (CMV) isolates infecting chilli and its interaction with host ferredoxin protein of different host for causing mosaic symptoms
Chilli ( Capsicum annuum L.) is an important vegetable crop grown in the Indian sub-continent and is prone to viral infections under field conditions....
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Purification and structural characterization of the Na+-translocating ferredoxin: NAD+ reductase (Rnf) complex of Clostridium tetanomorphum
Various microbial metabolisms use H + /Na + -translocating ferredoxin:NAD + reductase (Rnf) either to exergonically oxidize reduced ferredoxin by NAD + for...
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Customized exogenous ferredoxin functions as an efficient electron carrier
Ferredoxin (Fdx) is regarded as the main electron carrier in biological electron transfer and acts as an electron donor in metabolic pathways of many...
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Is reduced ferredoxin the physiological electron donor for MetVF-type methylenetetrahydrofolate reductases in acetogenesis? A hypothesis
The methylene-tetrahydrofolate reductase (MTHFR) is a key enzyme in acetogenic CO 2 fixation. The MetVF-type enzyme has been purified from four...
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Disulfiram downregulates ferredoxin 1 to maintain copper homeostasis and inhibit inflammation in cerebral ischemia/reperfusion injury
In the current study, we aimed to investigate whether disulfiram (DSF) exerts a neuroprotective role in cerebral ischemiareperfusion (CI-RI) injury...
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Systematic analysis based on the cuproptosis-related genes identifies ferredoxin 1 as an immune regulator and therapeutic target for glioblastoma
Glioblastoma multiforme (GBM) is recognized as the prevailing malignant and aggressive primary brain tumor, characterized by an exceedingly...
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Identification of functional cytochrome P450 and ferredoxin from Streptomyces sp. EAS-AB2608 by transcriptional analysis and their heterologous expression
AbstractBioconversion using microorganisms and their enzymes is an important tool in many industrial fields. The discovery of useful new microbial...
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Ferredoxin reductase and p53 are necessary for lipid homeostasis and tumor suppression through the ABCA1–SREBP pathway
p53 is known to modulate metabolism and FDXR is required for steroidogenesis. Given that FDXR is a target/regulator of p53, the FDXR–p53 axis may...
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An overview of the factors playing a role in cytochrome P450 monooxygenase and ferredoxin interactions
Cytochrome P450 monooxygenases (CYPs/P450s) are heme-thiolate proteins that are ubiquitously present in organisms, including non-living entities such...
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The structure of a triple complex of plant photosystem I with ferredoxin and plastocyanin
The ability of photosynthetic organisms to use sunlight as a sole source of energy is endowed by two large membrane complexes—photosystem I (PSI) and...
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The oxidoreductase activity of Rnf balances redox cofactors during fermentation of glucose to propionate in Prevotella
Propionate is a microbial metabolite formed in the gastrointestinal tract, and it affects host physiology as a source of energy and signaling...
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Cyanobakterien als nachhaltige Katalysatoren
Cyanobacteria can regenerate reaction equivalents like NADPH and ferredoxin by oxygenic photosynthesis; a unique process using light as energy source...
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Unravelling the role of transient redox partner complexes in P450 electron transfer mechanics
The molecular evolution of cytochromes P450 and associated redox-driven oxidative catalysis remains a mystery in biology. It is widely believed that...
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Molecular characterization of the missing electron pathways for butanol synthesis in Clostridium acetobutylicum
Clostridium acetobutylicum is a promising biocatalyst for the renewable production of n -butanol. Several metabolic strategies have already been...