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Nonfunctioning Pituitary Adenoma
Nonfunctioning pituitary adenomas (NFPAs) are the most benign adenohypophyseal tumors of various histological subtypes that are not linked with...
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Intraoperative cerebrospinal fluid leakage and residual tumors in endoscopic transsphenoidal surgery for pituitary adenoma: risk analysis and nomogram development
BackgroundEndoscopic transsphenoidal surgery is the primary method used to treat pituitary adenomas (PAs) at present; however, this technique is...
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Pituitary apoplexy: a systematic review of non-gestational risk factors
PurposePregnancy is a known risk factor for Pituitary Apoplexy (PA) but there is a lack of consistency in the literature regarding non-gestational...
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Giant growth hormone-secreting pituitary adenomas from the endocrinologist’s perspective
ObjectivesSince giant (≥40 mm) GH-secreting pituitary adenomas are rarely encountered, data on their characteristics and treatment outcomes are...
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Clinical characteristics and therapeutic outcomes of acromegalic patients with giant growth hormone-secreting pituitary adenomas: a single-center study of 67 cases
PurposeAcromegalic patients with giant growth hormone-secreting pituitary adenomas (GHPAs) (≥ 40 mm) are relatively rare, and their clinical...
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Comparative epigenomics indicate a common origin of ectopic and intrasellar corticotroph pituitary neuroendocrine tumors/adenomas: a case report
Ectopic pituitary neuroendocrine tumors (PitNET)/adenomas are rare and diagnostically challenging extra-sellar tumors. Previous studies have...
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Prognostic implication of size on outcomes of pituitary macroadenoma: a comparative analysis of giant adenoma with non-giant macroadenoma
BackgroundDue to the differences in size and invasiveness when compared to non-giant macroadenomas (nGPAs), giant pituitary adenomas (GPAs) are...
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Genetics of Pituitary Adenomas
Pituitary adenomas are usually benign tumours located in sella turcica, deriving from the pituitary anterior lobe. They represent the third most...
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Two- and three-dimensional endoscopic endonasal surgery of large and giant pituitary adenomas—outcome analysis of a series of 62 patients from a single pituitary center
To analyze the perioperative course and clinical outcome of patients with large (lPA) and giant (gPA) pituitary adenoma who underwent endoscopic...
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Non-functioning Pituitary Adenoma
This chapter discusses the group of non-functioning pituitary adenomas, their symptoms, laboratory and imaging features, and treatment issues.
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Diagnosis and management of prolactin-secreting pituitary adenomas: a Pituitary Society international Consensus Statement
This Consensus Statement from an international, multidisciplinary workshop sponsored by the Pituitary Society offers evidence-based graded consensus...
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Pituitary function at presentation and following therapy in patients with non-functional pituitary macroadenomas: a single centre retrospective cohort study
BackgroundNon-functioning pituitary macroadenomas (NFPMs) may present with hypopituitarism. Pituitary surgery and radiotherapy pose an additional...
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Disorders of the Hypothalamic–Pituitary Axis
The hypothalamic–pituitary axis is the translator of the function of higher central nervous system activity into endocrine activity through pituitary...
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Benign and Malignant Tumors of the Pituitary Gland
Pituitary glandPituitary gland tumors represent approximately 10–15% of all brain tumorsBrain tumor and the most common neoplasmsNeoplasm of the...
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Characteristics and overall survival in pediatric versus adult pituitary adenoma: a National Cancer Database analysis
ObjectivePituitary adenomas in the pediatric population are extremely rare, resulting in limited information in the literature on these patients. In...
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Pituitary surgery in Cushing’s disease: first line treatment and role of reoperation
Cushing’s disease is the most common cause of endogenous hypercortisolemia, and transsphenoidal surgery remains the first line therapy for removal of...
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Pituitary Disorders Affecting Linear Growth: Tall Stature
Growth hormone (GH) excess secondary to a pituitary adenoma may lead to gigantism in children and adolescents. Most pituitary tumors occur...
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Endoscopic trans-sphenoidal pituitary surgery does not impact postoperative nasal quality of life
PurposeThe aim of this prospective longitudinal study was to assess both subjective quality of life using questionnaires and objective examination of...
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Pituitary Adenoma
Pituitary adenomas account for about 85–90% of sellar lesions, commonly affecting the age group of fourth to seventh decade with a predilection for...
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The hallmarks of cancer… in pituitary tumors?
Over 20 years ago, Hanahan and Weinberg published a seminal review that addressed the biological processes that underly malignant transformation....
