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Lymph node ratio and hematological parameters predict relapse-free survival in patients with high grade rectal neuroendocrine neoplasms after radical resection: a multicenter prognostic study
BackgroundThe prognostic nutritional index (PNI), alkaline phosphatase (ALP), and lymph node ratio (LNR) are reportedly related to prognosis. The aim...
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Gastric NEN. III-2. Staging and Treatment
Gastric NENs are biologically different from gastric adenocarcinoma. For gastric NEMs, two staging systems for gastric NENs have been established:...
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A relook at gastroenteropancreatic neuroendocrine tumours as per 2019 WHO classification—A tertiary centre experience
IntroductionNeuroendocrine neoplasm of GIT (gastrointestinal tract) and pancreas is heterogenous with variable clinical features and disease...
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What have we learnt from the past – would treatment decisions for GEP-NET patients differ between 2012 to 2016 by the new recommendations in 2022?
BackgroundGastroenteropancreatic neuroendocrine tumors (GEP-NETs) are a heterogeneous group of tumors with a broad range of local and systemic...
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Overall Survival in Patients with Stage IV Pan-NET Eligible for Liver Transplantation
BackgroundThe use of liver transplantation (LT) in patients with stage IV neuroendocrine pancreatic tumors (pan-NET) is under debate. Previous...
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Pancreatic Neuroendocrine Neoplasms. V-2. Staging and Treatment
The term pancreatic neuroendocrine neoplasm (PNEN) encompasses a diverse set of tumors arising in the pancreas neuroendocrine progenitor cell. PNEN...
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Multi-institutional development and validation of a nomogram to predict recurrence after curative resection of gastric neuroendocrine/mixed adenoneuroendocrine carcinoma
ObjectiveTo establish a novel nomogram to predict individual 1, 3, and 5 years disease-free survival (DFS) of patients with gastric neuroendocrine...
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Diagnostic Applications of Nuclear Medicine: Neuroendocrine Tumors
Neuroendocrine tumors (NETs) originate from neuroendocrine cells ubiquitously distributed throughout the body and occur mainly in the...
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Diagnostic Applications of Nuclear Medicine: Neuroendocrine Tumors
Neuroendocrine tumors (NETs) originate from neuroendocrine cells ubiquitously distributed throughout the body and occur mainly in the...
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Prophylactic cholecystectomy is not mandatory in patients candidate to the resection for small intestine neuroendocrine neoplasms: a propensity score-matched and cost-minimization analysis
To evaluate two competitive strategies in patients undergoing resection of Small-intestine neuroendocrine neoplasms (Si-NEN): prophylactic...
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Increased neutrophil–lymphocyte ratio predicts recurrence in patients with well-differentiated pancreatic neuroendocrine neoplasm based on the 2017 World Health Organization classification
BackgroundThe prognostic values of inflammation-based markers in well-differentiated pancreatic neuroendocrine neoplasms, diagnosed according to the...
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Co-existing Neuroendocrine Tumors in the Ileum and Pancreas: A Clinico-Pathological Challenge
Ileal (I) and pancreatic (Pan) neuroendocrine tumors (NETs) are among the most common digestive neuroendocrine neoplasms (NENs). Coexisting NETs at...
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Staging and Treatment. II-1. Staging and Prognosis
Accurate diagnosis and/or staging of appendiceal tumors is essential due to recent advances in treatment. However, the classification and terms of...
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Staging and Treatment. II-2. Overview of Treatment According to Stage
The prognosis and treatment of appendiceal cancer differ according to histological type. There is controversy regarding the treatment strategy owing...
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From morphology to molecular targets—the pathologist’s view in diagnosing gastroenteropancreatic neuroendocrine neoplasms
In the last decade, a number of genetic alterations in gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) have been identified. In addition,...
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Appendiceal Tumors
Appendiceal adenocarcinoma was first described by Berger in 1882 [1], whereas a tumor arising from neuroendocrine cells [neuroendocrine tumors...
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Prognostic significance of laterality in lung neuroendocrine tumors
Purpose:Well-differentiated lung neuroendocrine tumors (Lu-NET) are classified as typical (TC) and atypical (AC) carcinoids, based on mitotic counts...
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Grading Solid Pseudopapillary Tumors of the Pancreas: the Fudan Prognostic Index
BackgroundKi-67 has been shown to predict outcome of patients with solid pseudopapillary tumor of the pancreas (SPTP) but has not been incorporated...
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Radical Resection in Entero-Pancreatic Neuroendocrine Tumors: Recurrence-Free Survival Rate and Definition of a Risk Score for Recurrence
BackgroundSurgery with radical intent is the only potentially curative option for entero-pancreatic neuroendocrine tumors (EP-NETs) but many patients...
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Rachel score: a nomogram model for predicting the prognosis of lung neuroendocrine tumors
BackgroundLung NET, classified in typical carcinoids (TC) and atypical carcinoids (AC), are highly heterogeneous in their biology and prognosis. The...
