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Oritavancin Versus Daptomycin for Osteomyelitis Treatment After Surgical Debridement
IntroductionWeekly intravenous (IV) oritavancin and daily daptomycin were compared in an outpatient setting following extensive surgical debridement...
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The Combination of Daptomycin with Fosfomycin is More Effective than Daptomycin Alone in Reducing Mortality of Vancomycin-Resistant Enterococcal Bloodstream Infections: A Retrospective, Comparative Cohort Study
IntroductionHigh-dose daptomycin-based combinations are recommended for vancomycin-resistant Enterococcus (VRE) bloodstream infection (BSI)....
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A Pharmacovigilance Analysis of Daptomycin Use Based on CLSI Susceptible Dose-Dependent Category
IntroductionDaptomycin doses 8–12 mg/kg are recommended for susceptible dose-dependent Enterococcus species. However, data remain limited on safety...
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The effects of daptomycin on cell wall biosynthesis in Enterococcal faecalis
Daptomycin is a cyclic lipodepsipeptide antibiotic reserved for the treatment of serious infections by multidrug-resistant Gram-positive pathogens....
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Dual release of daptomycin and BMP-2 from a composite of β-TCP ceramic and ADA gelatin
BackgroundAntibiotic-containing carrier systems are one option that offers the advantage of releasing active ingredients over a longer period of...
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Usefulness of daptomycin lock therapy in children with catheter-related bacteremia after failed vancomycin lock therapy
PurposeCatheter-related bacteremia (CRB) is a significant cause of morbidity, resource expenditure and prolonged hospital stays in patients with...
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Population Pharmacokinetic Model for Unbound Concentrations of Daptomycin in Patients with MRSA Including Patients Undergoing Hemodialysis
Background and ObjectiveUnbound daptomycin concentrations are responsible for pharmacologically beneficial and adverse effects, although most...
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Vancomycin and daptomycin dosing recommendations in patients receiving home hemodialysis using Monte Carlo simulation
BackgroundFew drug dosing recommendations for patients receiving home hemodialysis (HHD) have been published which has hindered the adoption of HHD....
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Challenges in managing a multifactorial eosinophilic pneumonia: daptomycin vs strongyloidiasis case report
BackgroundEosinophilia is defined as a blood eosinophil count > 500/mcL with etiology usually an allergic reaction or parasitic infection which can...
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Population Analysis of Daptomycin-non-Susceptible Methicillin-Resistant Staphylococcus aureus Reveals the Presence of Variants That Contribute to Daptomycin Resistance
In this study, population analysis (PA) of methicillin-resistant Staphylococcus aureus (MRSA), before and after long-duration daptomycin (DAP)...