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Locusta migratoria hydrolysates attenuate lipopolysaccharide (LPS)/D-Galactosamine (D-Gal)-induced cytotoxicity and inflammation in Hep G2 cells via NF-κB signaling suppression
The prolonged state of hepatic inflammation can lead to liver damage, a critical driving force in the progression of liver-related diseases. Locusta...
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Janus kinase inhibitor Tofacitinib alleviated acute hepatitis induced by lipopolysaccharide/D-galactosamine in mice
Background:The Janus kinase (JAK) is a crucial intracellular signaling hub for numerous cytokines, which is extensively involved in the activation of...
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Naringin alleviates liver damage induced by D-galactosamine (D-gal) in mice through down-regulation of CYP2E1 and P53 hyperactivity
Cytochrome P450 2E1 (CYP2E1) plays an important role in liver damage. However, it is still unclear how CYP2E1 transcriptional regulation works....
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Characteristics of the intestinal bacterial microbiota profiles in Bifidobacterium pseudocatenulatum LI09 pre-treated rats with D-galactosamine-induced liver injury
Bifidobacterium pseudocatenulatum LI09 could prevent D-galactosamine-induced liver injury. Our previous study has preliminarily determined that...
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Antiapoptotic Effect of Pyrimidine-Derived Drug Xymedon and Its Conjugate with L-Ascorbic Acid on Chang Liver Cells Under Apoptosis Induced by d-Galactosamine
The present study aims to evaluate the effect of the pyrimidine-derived drug Xymedon and its conjugate with L-ascorbic acid, which exerts...
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Synthesis and Inhibitory Activity of Atorvastatin Conjugate with a Branched Asialoglycoprotein Receptor Ligand Containing Three N-Acetyl-d-galactosamine Residues
AbstractA novel atorvastatin conjugate was synthesized by a multistep procedure, using a branched N -acetylgalactosamine ligand for...
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Co-administration of lipopolysaccharide and d-galactosamine induces genotoxicity in mouse liver
The acute liver injury (ALI) and hepatic fibrosis caused by the co-treatment of lipopolysaccharide (LPS)/ d -galactosamine (D-GalN) have been...
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Sleep deprivation aggravated lipopolysaccharide/d-galactosamine-induced acute liver injury by suppressing melatonin production
ObjectiveSleep loss is common in patients with liver injury, but the effects of sleep deprivation (SD) on liver injury remain unclear. In the present...
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Protective effects of apigenin, apigenin-8-sulfonate, and apigenin-3′, 8-disulfonate on d-galactosamine-induced acute liver damage in mice
The water-soluble sulfated derivatives, apigenin-8-sulfonate sodium (AS) and apigenin-3′, 8-disulfonate sodium (ADS) derived from parent apigenin...
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Retraction Note: Sedum sarmentosum Bunge extract ameliorates lipopolysaccharide- and D-galactosamine-induced acute liver injury by attenuating the hedgehog signaling pathway via regulation of miR-124 expression
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12906-020-2873-1.
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Lactobacillus salivarius LI01 encapsulated in alginate-pectin microgels ameliorates d-galactosamine-induced acute liver injury in rats
AbstractAcute liver failure is a clinical emergency associated with high mortality. Accumulating evidence indicates that gut microbiota participates...
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Hepatoprotective Phenylpropanoid Glycosides from Highland Barley Monascus purpureus
A new phenylpropanoid glycoside, named 4-O- β -D-glucopyranosyl-7-phenyl-9-propenyl ketone-9-O- β -Dglucopyranosyl-(6′′→1′′′)-6′′-O-α-L-rhamnopyranose ( 1 )...
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Comparison of Extracellular Matrix (ECM) of Normal and D-Galactosamine-Induced Mice Model of Liver Injury Before and After Liver Decellularization
AbstractDecellularization is a process that has gained importance in the newly emerging field of tissue engineering and regenerative medicine. The...
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The Structure of Sulfated Polysaccharides from the Sea Cucumber Holothuria (Stauropora) fuscocinerea
Abstract —Fucosylated chondroitin sulfate FCS-Hf and preparations of fucan sulfates Hf-Fuc1 and Hf-Fuc2 were isolated from the Vietnamese sea...
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Synthesis of a new betulinic acid glycoconjugate with N-acetyl-d-galactosamine for the targeted delivery to hepatocellular carcinoma cells
A new promising conjugate of betulinic acid with N -acetyl- d -galactosamine was synthesized by the simple reaction sequence: esterification and...
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Protective effect of apigenin on d-galactosamine/LPS-induced hepatocellular injury by increment of Nrf-2 nucleus translocation
Apigenin has a protective effect on d -galactosamine ( d -GalN)/lipopolysaccharide (LPS)-induced mouse liver injury through the increments of hepatic...
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Hepatitis
This chapter introduces the effects of arabinoxylan rice bran (Biobran) on hepatitis in animals and humans based on evidence-based research papers....
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Combination of Phycocyanin, Zinc, and Selenium Improves Survival Rate and Inflammation in the Lipopolysaccharide-Galactosamine Mouse Model
Sepsis is related to systemic inflammation and oxidative stress, the primary causes of death in intensive care units. Severe functional abnormalities...
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Comparative Analysis of Physicochemical Characteristics of Chondroitin Sulfate from Avian Cartilage: Antioxidant, Anti-inflammatory and Anti-nociceptive Properties
In this study, chondroitin sulfate (CS) was isolated from the sternum cartilage of fully-grown chickens ( Gallus gallus) and turkeys ( Meleagris...
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RETRACTED ARTICLE: Sedum sarmentosum Bunge extract ameliorates lipopolysaccharide- and D-galactosamine-induced acute liver injury by attenuating the hedgehog signaling pathway via regulation of miR-124 expression
BackgroundSedum sarmentosum is traditionally used to treat various inflammatory diseases in China. It has protective effects against acute liver...
