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Recombinant Biogenesis and Analysis of Cytochrome c Species
Recombinant expression and biogenesis of cytochrome c species is a simple and efficient method for the production of holocytochrome c species, thus... -
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Electrostatic effects on water-soluble fullerene derivatives interaction with cytochrome c and cytochrome c oxidase
Water-soluble fullerene derivatives are good candidates for various biological applications such as anticancer or antimicrobial therapy,...
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Peculiarities of Cytochrome c Enzymatic Activity with Cardiolipin
AbstractThe points of enzymatic activity, quantum yields, structure, functions of luminol chemiluminescence activated by physical activators natural...
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Diverse functions of cytochrome c in cell death and disease
The redox-active protein cytochrome c is a highly positively charged hemoglobin that regulates cell fate decisions of life and death. Under normal...
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Altered conformational dynamics contribute to species-specific effects of cytochrome c mutations on caspase activation
Variants in the gene encoding human cytochrome c ( CYCS ) cause mild autosomal dominant thrombocytopenia. Despite high sequence conservation between...
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Pirh2 modulates the mitochondrial function and cytochrome c-mediated neuronal death during Alzheimer’s disease
Pirh2 is an E3 ubiquitin ligase known to regulate the DNA damage responses through ubiquitylation of various participating signaling factors. DNA...
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Artesunate acts through cytochrome c to inhibit growth of pediatric AML cells
Artesunate is a derivative of artemisinin, an active compound isolated from Artemisia annua which has been used in Traditional Chinese Medicine and...
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Phosphorylation disrupts long-distance electron transport in cytochrome c
It has been recently shown that electron transfer between mitochondrial cytochrome c and the cytochrome c 1 subunit of the cytochrome bc 1 can proceed...
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C-C bond cleavage reactions catalyzed by cytochrome P450 enzymes
Cytochrome P450 (P450, CYP) enzymes are the major catalysts involved in drug metabolism, as well as general oxidations of vitamins, steroids, natural...
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Construction of a cytochrome c nanosensor based on nano-engineered cytochrome oxidase enzyme covalently immobilized on AuNPs-GrNs nanocomposite-modified pencil graphite electrode
Cytochrome c (cyt c) has been suggested as a diagnostic biomarker for non-small cell lung cancer (NSCLC) screening and is a confirmatory method for...
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Recurrent evolutionary switches of mitochondrial cytochrome c maturation systems in Archaeplastida
Mitochondrial cytochrome c maturation (CCM) requires heme attachment via distinct pathways termed systems I and III. The mosaic distribution of these...
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A Case Study of Cytochrome c
Direct electrochemistry of immobilized proteins is a fundamental issue for practical biotech applications. Cytochrome c (Cyt c) has been widely used... -
Cajanus cajan induces mitochondrial-mediated apoptosis via caspase activation and cytochrome c release
BackgroundAttention has recently focused on mitochondrial-mediated apoptosis as a signaling pathway that is disrupted in many diseases involving...
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Modeling of Quantum Yields, Structure and Function of Cytochrome C and Cardiolipin: Its Enzymatic Activity and Free Radical Processes
AbstractQuantum yields, structure, and enzymatic activity points of coumarin–activated C-334 chemiluminescence of lipid peroxidation processes under...
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Dexmedetomidine attenuates postoperative spatial memory impairment after surgery by reducing cytochrome C
BackgroundAnesthesia and surgery can induce perioperative neurocognitive disorders (PND). Mitochondrial dysfunction has been proposed to be one of...
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Implementation of cytochrome c proteins and carbon nanotubes hybrids in bioelectrodes towards bioelectrochemical systems applications
Multiheme cytochrome c (Cyt c) can function as a redox protein on electrode to accomplish bioelectrocatalysis. However, the direct electron transfer...
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The effect of cytochrome c on Na,K-ATPase
Na,K-ATPase is a crucial enzyme responsible for maintaining Na + , K + -gradients across the cell membrane, which is essential for numerous physiological...
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Drop-casted Photosystem I/cytochrome c multilayer films for biohybrid solar energy conversion
One of the main barriers to making efficient Photosystem I-based biohybrid solar cells is the need for an electrochemical pathway to facilitate...
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Modeling of the Interaction of Cytochrome c with Cardiolipin
AbstractInteractions of horse heart cytochrome c (Cyt c ) with cardiolipin molecules were modeled by molecular dynamics simulations. It was shown...