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Molecular definition of the endogenous Toll-like receptor signalling pathways
Innate immune pattern recognition receptors, such as the Toll-like receptors (TLRs), are key mediators of the immune response to infection and...
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Quantum No-signalling Correlations and Non-local Games
We introduce and examine three subclasses of the family of quantum no-signalling (QNS) correlations introduced by Duan and Winter: quantum commuting,...
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Mosaic composition of RIP1–RIP3 signalling hub and its role in regulating cell death
RIP1 and RIP3, cell death mediators, form fibrous amyloids. How RIP1/RIP3 amyloidal oligomers assemble functional necrosomes and control cell death...
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Environmental colour pattern variation in Mediterranean Podarcis
BackgroundLizards of the genus Podarcis are widespread in the Mediterranean region, including islands and island archipelagos. These small-bodied...
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Low-loss microwave photonics links using hollow core fibres
There are a host of applications in communications, sensing, and science, in which analogue signal transmission is preferred over today’s dominant...
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Artificial nighttime lighting impacts visual ecology links between flowers, pollinators and predators
The nighttime environment is being altered rapidly over large areas worldwide through introduction of artificial lighting, from streetlights and...
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Black-and-white pelage as visually protective coloration in colobus monkeys
AbstractConspicuous coloration is often seen as the evolutionary consequence of either sexual selection or warning predators visually about prey...
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High-throughput Oligopaint screen identifies druggable 3D genome regulators
The human genome functions as a three-dimensional chromatin polymer, driven by a complex collection of chromosome interactions
1 –3 . Although the... -
Variability, heritability and condition-dependence of the multidimensional male colour phenotype in a passerine bird
Elaborate ornamental traits are commonly assumed to be honest signals of individual quality, owing to the presumed costs involved in their production...
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Ecological drivers of ultraviolet colour evolution in snakes
Ultraviolet (UV) colour patterns invisible to humans are widespread in nature. However, research bias favouring species with conspicuous colours...
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Avian nuptial plumage coloration changes differently when exposed to urban and rural areas
AbstractAvian plumage coloration could be altered by external factors like dust accumulation, but the effect of environmental conditions on such...
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Colouration matters in dull toads: ultraviolet adornment for ladies and agrochemicals fading effects
Integument colouration can influence many aspects of fitness, and is under strong sexual selection. Amphibians often express sexual dichromatism, and...
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India’s Tiraṅgā at the Confluence of Postcolonial Nationalism, Cosmopolitan Aspirations, and Chromatic Social Cognition: “Saffronising” Democracy?
The tricoloured flag India adopted in 1947 to mark its independence from Britain, the Tiraṅgā, results in fact from the combination of four elements... -
Ontogenetic colour change of a sexual ornament in males of a damselfly: female mimicry, crypsis or both?
Female mimicry by males is a widespread phenomenon in several taxa and may be involved in aggression avoidance or facilitated access to resources. In...
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Architecture and dynamics of a desmosome–endoplasmic reticulum complex
The endoplasmic reticulum (ER) forms a dynamic network that contacts other cellular membranes to regulate stress responses, calcium signalling and...
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CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours
Chimeric antigen receptor (CAR) therapy has had a transformative effect on the treatment of haematologic malignancies
1 –6 , but it has shown limited... -
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Astrocytes close a motor circuit critical period
Critical periods—brief intervals during which neural circuits can be modified by activity—are necessary for proper neural circuit assembly. Extended...
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Visual antipredator effects of web flexing in an orb web spider, with special reference to web decorations
Some visual antipredator strategies involve the rapid movement of highly contrasting body patterns to frighten or confuse the predator. Bright body...
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Zinc Acts Synergistically with Berberine for Enhancing Its Efficacy as an Anti-cancer Agent by Inducing Clusterin-Dependent Apoptosis in HT-29 Colorectal Cancer Cells
It is now widely accepted that anti-cancer medications are most effective when administered in combination. Zinc is an essential micronutrient whilst...