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Cell Cycle Control Methods and Protocols
This detailed volume collects techniques to study the highly regulated cell cycle process. Beginning with chapters investigating these processes and...
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Cell Cycle Map** Using Multiplexed Immunofluorescence
The development of technologies that allow measurement of the cell cycle at the single-cellSingle-cell level has revealed novel insights into the...
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Cell-Cycle Synchronization Methods and Protocols
This volume covers a broad range of cell types including cultured cell lines, primary cells, and various unicellular organisms such as fission yeast,...
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Investigating Heterogeneous Cell-Cycle Progression Using Single-Cell Imaging Approaches
Investigating cell-cycle progression has been challenging due to the complex interconnectivity of regulatory processes and inherent cell-to-cell...
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Cell Cycle and Cancer
Cancer is the second leading cause of mortality worldwide. It is an anomalous condition in which cell growth bypasses all the normal restraints on...
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An alternative cell cycle coordinates multiciliated cell differentiation
The canonical mitotic cell cycle coordinates DNA replication, centriole duplication and cytokinesis to generate two cells from one
1 . Some cells, such...
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Senescence and Cell Cycle Control
In response to various stresses, such as telomere shortening during continuous proliferation, oxidative stress, DNA damage and aberrant oncogene...
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Cell Cycle Regulation in Mammalian Germ Cells
Meiosis is a unique form of cellular division by which a diploid cell produces genetically distinct haploid gametes. Initiation and regulation of...
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Cell Cycle
The basis for reproduction of all organisms is a process called the cell cycle [75]. As the name implies, the cell cycle is an iterative, periodic...
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Mouse Models of Cell Cycle Regulators: New Paradigms
In yeast, a single cyclin-dependent kinase (Cdk) is able to regulate diverse cell cycle transitions (S and M phases) by associating with multiple...
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Cell Cycle Dysregulation in Breast Cancer
Cancer, a condition characterized by abnormal cell growth, is closely linked to the cell cycle. In reaction to mitogenic cues, all malignancies...
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Systems biology of the yeast cell cycle engine
One goal of systems biology is to obtain an integrated understanding of the physiological properties of cells from the detailed molecular machinery...
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Introduction to Cell Cycle and Its Regulators
The extremely complicated chain of associations among cytokines, proteins, enzymes, and cell cycle signaling pathways orchestrates cell cycle...
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Liquiritigenin Induces Cell Cycle Arrest and Apoptosis in Lung Squamous Cell Carcinoma
Liquiritigenin (LQ), as a dihydroflavone monomer compound extracted from Glycyrrhiza uralensis Fisch, has been demonstrated to show anti-tumor...
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Therapeutic potential of Cell Cycle Kinases in Breast Cancer
This book highlights the interrelation between cell cycle regulators and breast cancer phenotypes. It reviews the roles of Cyclin-Dependent Kinases...
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The ubiquitin-proteasome pathway in cell cycle control
Ubiquitin-mediated proteolysis is one of the key mechanisms underlying cell cycle control. The removal of barriers posed by accumulation of...
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Cell Structure and Function, Cell Division and Cell Cycle, Cell Types and Stem Cells
Knowledge of cells is essential for understanding human health and disease. This chapter deals with cellular structure and function, communications...
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Cross Talk Between Metabolism and the Cell Division Cycle
Cell division requires a massive rewiring of cellular pathways, including molecular routes involved in providing energy for cell survival and...
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FUCCI Reporter Gene-Based Cell Cycle Analysis
One of the most commonly assessed parameters in cellular analyses is the proliferative activity of a cell population. The fluorescence ubiquitin cell...
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Modeling Cell Cycle Control and Cancer with pRB Tumor Suppressor
Cancer is a complex syndrome of diseases characterized by the increased abundance of cells that disrupts the normal tissue architecture within...