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3,3′-Diindolylmethane and indole-3-carbinol: potential therapeutic molecules for cancer chemoprevention and treatment via regulating cellular signaling pathways
Dietary compounds in cancer prevention have gained significant consideration as a viable method. Indole-3-carbinol (I3C) and 3,3′-diindolylmethane...
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Indole-3-carbinol in vitro antiviral activity against SARS-Cov-2 virus and in vivo toxicity
The effects of indole-3-carbinol (I3C) compound have been described deeply as antitumor drug in multiple cancers. Herein, I3C compound was tested for...
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Indole-3-carbinol (I3C) reduces apoptosis and improves neurological function after cerebral ischemia–reperfusion injury by modulating microglia inflammation
Indole-3-carbinol(I3C) is a tumor chemopreventive substance that can be extracted from cruciferous vegetables. Indole-3-carbinol (I3C) has been shown...
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Pharmacokinetic and Pharmacodynamic Properties of Indole-3-carbinol in Experimental Focal Ischemic Injury
Background and ObjectivesIndole-3-carbinol (I3C) is reported to have neuroprotective properties in an animal model of ischemic stroke. However, the...
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The Effect of Methyl Isobutyl Carbinol “MIBC” on the Froth Stability and Flotation Performance of Low-Grade Phosphate Ore
As freshwater resources are becoming scarce, the use of seawater as replacement of fresh water is appealing in order to make mineral processing...
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Assessment by the Fluorescence Imaging Methods of the Antitumor Efficacy and Apoptotic Activity of Biologically Active Additives Containing Resveratrol, Indole-3-Carbinol, and Cordycepin in Human Renal Carcinoma Cells
AbstractThe efficacy of antitumor efficacy and apoptosis induction in A498 human renal cell carcinoma observed when applying extracts of cruciferous...
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Antitumor Activity of Indole-3-carbinol in Breast Cancer Cells: Phenotype, Genetic Pattern, and DNA Methylation Inversion
The effect of indole-3-carbinol on the proliferation and migration of MDA-MB-231 breast-cancer cells and healthy MCF-10A breast-tissue cells has been...
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Cruciferous Vegetables (Indole-3-Carbinol, Isothiocyanates) Against Cancer
During the years, numerous evidence reported the extraordinary power of nutrition in both prevention and management of several chronic diseases,... -
Indole-3-carbinol regulates microglia homeostasis and protects the retina from degeneration
BackgroundRetinal degenerative diseases significantly contribute to visual impairment and blindness. Microglia reactivity is a hallmark of...
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Indole-3-carbinol alleviates carbon tetrachloride-induced liver injury by inhibiting inflammatory response and regulating lipid metabolism
The hepatoprotective effects of indole-3-carbinol (I3C), one of the byproducts of the breakdown of glucosinolate glucobrassicin, were examined in...
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Transient Phase State of Organic Liquids in Thin Layers
AbstractThe work discusses the IR study of transient phase state formation in thin layers on solid surface, generated at variable temperature in the...
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Effect of cold arid high-altitude environment on bioactive phytochemical compounds of organically grown Brassicaceae vegetables for nutri-health security in mountainous regions
High-altitude (HA) environment presents immense physiological adversities for humans that have been overcome by supplementing bio-active...
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STRUCTURE AND THERMODYNAMIC CHARACTERISTICS OF INTERMEDIATE CATALYTIC ADDUCTS IN CUMENE OXIDATION IN THE PRESENCE OF 2-ETHYLHEXANOATES OF GROUP 2 METALS
AbstractThe kinetics of cumene oxidation in the presence of Mg, Ca, Sr, Ba 2-ethylhexanoates is studied experimentally. It is established that the Mg...
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Interaction of Acetylenic Alcohols with the Coal’s Surface during Flotation
If acetylenic alcohols are used as flotation reagents for coal, coal extraction in the concentrates is increased, the concentrate yield is improved,...
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Therapeutic Implications and Regulations of Protein Post-translational Modifications in Parkinsons Disease
Parkinsons disease (PD) is a neurodegenerative disorder characterized by dopaminergic neuron loss and alpha-synuclein aggregation. This comprehensive...
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An Additional Condition of Efficiency of the Supercritical Fluid Extraction Process
AbstractThe extraction of valuable components (methyl phenyl carbinol, acetophenone, ethylbenzene, phenol, propylene glycol) from industrial...
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Efficient malachite green biodegradation by Pseudomonas plecoglossicide MG2: process optimization, application in bioreactors, and degradation pathway
Microbial degradation of synthetic dyes is considered a promising green dye detoxification, cost-effective and eco-friendly approach. A detailed...
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Extraction and Isolation of Secondary Metabolites from Apocynaceae Plants
Secondary metabolites are compounds produced by plants that are not directly involved in growth and development but instead are involved in various... -
Synthesis of New Silicone-based Adducts to Functionalize Cotton Fabric
New silicone based adducts were synthesized by reacting equimolar ratio of carbinol polydimethylsiloxane (CPDMS), 2,4-toluene diisocyanate (TDI) and...
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Inducibility of Metabolizing Enzymes
Metabolic enzyme inducibility is of major significance, because it plays an important role in the susceptibility of individuals to foreign...