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Brivaracetam (BRV)
Das Kapitel zeigt tabellarisch das Kurzprofil des Medikaments Brivaracetam (BRV). -
Brivaracetam
The pharmacokinetic characteristics of brivaracetam are described and the interaction effects of concomitant antiseizure medications on brivaracetam... -
Brivaracetam
The effect of alcohol, gemfibrozil, oral contraceptives, and rifampicin on the pharmacokinetics of brivaracetam is described. Also, potential... -
Brivaracetam and topiramate serum levels during pregnancy and delivery: a case report and a review of literature
BackgroundAn increasing use of newer antiseizure medication (ASM) such as SV2A ligand brivaracetam is observed. However, data on newer antiseizure...
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Brivaracetam use in clinical practice: a Delphi consensus on its role as first add-on therapy in focal epilepsy and beyond
BackgroundAntiseizure medications remain the cornerstone of treatment for epilepsy, although a proportion of individuals with the condition will...
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Conversion to Brivaracetam Monotherapy in Clinical Practice: A Retrospective Study
IntroductionThe study aimed to evaluate the effectiveness and safety of brivaracetam (BRV) as conversion monotherapy in adults with focal epilepsy...
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Adjunctive Brivaracetam in Older Patients with Focal Seizures: Evidence from the BRIVAracetam add‑on First Italian netwoRk Study (BRIVAFIRST)
BackgroundThe management of epilepsy in older adults has become part of daily practice because of an aging population. Older patients with epilepsy...
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Investigating clinical pharmacokinetics of brivaracetam by using a pharmacokinetic modeling approach
The development of technology and the processing speed of computing machines have facilitated the evaluation of advanced pharmacokinetic (PK) models,...
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Anti-convulsant Agents: Levetiracetam and Brivaracetam
Levetiracetam (LEV) and brivaracetam (BRV) are pyrrolidone derivate compounds binding at the presynaptic SV2A receptor site and thus representing... -
The impact of brivaracetam on cognitive processes and anxiety in various experimental models
BackgroundMemory deficits and anxiety symptoms are undesirable effects that occur in epilepsy patients. They may be associated with the...
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Development of SV2A Ligands for Epilepsy Treatment: A Review of Levetiracetam, Brivaracetam, and Padsevonil
Epilepsy is a common neurological disorder that is primarily treated with antiseizure medications (ASMs). Although dozens of ASMs are available in...
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Narrative Review of Brivaracetam: Preclinical Profile and Clinical Benefits in the Treatment of Patients with Epilepsy
One third of patients with epilepsy will continue to have uncontrolled seizures despite treatment with antiseizure medications (ASMs). There is...
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Brivaracetam as Early Add-On Treatment in Patients with Focal Seizures: A Retrospective, Multicenter, Real-World Study
IntroductionIn randomized controlled trials, add-on brivaracetam (BRV) reduced seizure frequency in patients with drug-resistant focal epilepsy. Most...
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Effectiveness and Tolerability of 12-Month Brivaracetam in the Real World: EXPERIENCE, an International Pooled Analysis of Individual Patient Records
Background and ObjectiveReal-world evidence studies of brivaracetam (BRV) have been restricted in scope, location, and patient numbers. The objective...
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