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Efficacy of Αtezolizumab–Βevacizumab in BCLC-C cirrhotic patients with hepatocellular carcinoma according to the type of disease progression, the type of BCLC-C and liver disease severity
PurposeThe aim of our study was to evaluate, under real-life conditions, survival of patients with advanced HCC (BCLC-C), either initially presenting...
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Prognosis and safety of laparoscopic hepatectomy for BCLC stage 0/A hepatocellular carcinoma with clinically significant portal hypertension: a multicenter, propensity score-matched study
Background and aimThe latest Barcelona Clinic Liver Cancer (BCLC) staging system suggests considering surgery in patients with resectable BCLC stage...
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Surgical resection for large hepatocellular carcinoma and those beyond BCLC: systematic review with proposed management algorithm
BackgroundHepatocellular carcinoma (HCC) accounts for the sixth most common cancer and ranks third in mortality worldwide with inhomogeneity in terms...
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Bi-regional dynamic contrast-enhanced MRI for prediction of microvascular invasion in solitary BCLC stage A hepatocellular carcinoma
ObjectivesTo construct a combined model based on bi-regional quantitative dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), as well as...
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TARE in Hepatocellular Carcinoma: From the Right to the Left of BCLC
The Barcelona Clinic Liver Cancer (BCLC) system is the most commonly used staging system for hepatocellular carcinoma (HCC) in Western countries....
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Laparoscopic versus open liver resection for resectable HCC with BCLC stage B: a propensity score-matched analysis
To date, there is little knowledge about the value of laparoscopic liver resection (LLR) for hepatocellular carcinoma (HCC) patients with Barcelona...
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Overall survival and toxicity of Y90 radioembolization for hepatocellular carcinoma patients in Barcelona Clinic Liver Cancer stage C (BCLC-C)
IntroductionNational Comprehensive Cancer Network HCC guidelines recommend Y90 to treat BCLC-C patients only in select cases given the development of...
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Hepatic artery intervention combined with immune-targeted therapy is superior to sequential therapy in BCLC-C hepatocellular carcinoma
BackgroundHepatic artery intervention combined with immunotarget therapy exerts excellent disease control and prolongs survival. However, the...
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A prospective observational cohort study of lenvatinib as initial treatment in patients with BCLC-defined stage B hepatocellular carcinoma
BackgroundTransarterial chemoembolization (TACE) is the standard treatment for intermediate stage hepatocellular carcinoma (HCC) (Barcelona Clinic...
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The survival strength of younger patients in BCLC stage 0-B of hepatocellular carcinoma: basing on competing risk model
BackgroundThe number of young patients with hepatocellular carcinoma (HCC) is increasing, but whether patients of different ages have a survival...
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Prognostic Value of Serum α‐Fetoprotein Level as an Important Characteristic of Tumor Biology for Patients Undergoing Liver Resection of Early-Stage Hepatocellular Carcinoma (BCLC Stage 0/A): A Large Multicenter Analysis
Background and ObjectiveAccording to the Barcelona Clinic Liver Cancer (BCLC) algorithm, tumor burden and liver function, but not tumor biology, are...
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Perioperative and long-term survival outcomes of laparoscopic versus laparotomic hepatectomy for BCLC stages 0–A hepatocellular carcinoma patients associated with or without microvascular invasion: a multicenter, propensity score matching analysis
PurposeTo analyze the long-term oncological outcomes of Barcelona Clinic Liver Cancer (BCLC) stages 0–A hepatocellular carcinoma (HCC) patients...
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Intermediate-stage (BCLC stage B) infiltrative hepatocellular carcinoma: safety and efficacy of chemoembolization
ObjectivesTo evaluate the safety and efficacy of chemoembolization in patients with intermediate-stage infiltrative Hepatocellular carcinoma (HCC).
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A simple CD4+ T cells to FIB-4 ratio for evaluating prognosis of BCLC-B hepatocellular carcinoma: a retrospective cohort study
IntroductionImmunotherapy has become a new therapy for advanced hepatocellular carcinoma (HCC); however, its treatment results are considerably...
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A new model to estimate duration of survival in patients with hepatocellular carcinoma with BCLC intermediate stage
It is difficult to determine whether an individual therapy contributes to the elongation of survival because of the difficulty of organizing clinical...
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Comparing Real World, Personalized, Multidisciplinary Tumor Board Recommendations with BCLC Algorithm: 321-Patient Analysis
PurposeTo evaluate hepatocellular carcinoma (HCC) treatment allocation, deviation from BCLC first-treatment recommendation, and outcomes following...
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Comparison of the prognosis of BCLC stage A ruptured hepatocellular carcinoma patients after undergoing transarterial chemoembolization (TACE) or hepatectomy: a propensity score-matched landmark analysis
BackgroundAt present, the choice of treatment modalities for ruptured hepatocellular carcinoma patients in BCLC stage A remains controversial, and...