Search
Search Results
-
Implications of Genetic Factors and Modifiers in Autism Spectrum Disorders: a Systematic Review
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition. Genetic, environmental, and epigenetic variables are all likely to have a...
-
Identification of four novel hub genes as monitoring biomarkers for colorectal cancer
BackgroundIt must be admitted that the incidence of colorectal cancer (CRC) was on the rise all over the world, but the related treatment had not...
-
Role of the interaction between troponin T and AMP deaminase by zinc bridge in modulating muscle contraction and ammonia production
The N-terminal region of troponin T (TnT) does not bind any protein of the contractile machinery and the role of its hypervariability remains...
-
Role of AMP deaminase in diabetic cardiomyopathy
Diabetes mellitus is one of the major causes of ischemic and nonischemic heart failure. While hypertension and coronary artery disease are frequent...
-
Association Between Total Genotype Score and Muscle Injuries in Top-Level Football Players: a Pilot Study
BackgroundRecently, genetic predisposition to injury has become a popular area of research and the association between a few single nucleotide...
-
Improved skeletal muscle fatigue resistance in experimental autoimmune myositis mice following high-intensity interval training
BackgroundMuscle weakness and decreased fatigue resistance are key manifestations of systemic autoimmune myopathies (SAMs). We here examined whether...
-
Integration of Genetic and Phenoty** Data for Sports Medicine
Sports medicine has had considerable success in different domains, including injury prevention, disease treatment, and patient recovery. By...
-
Disorders of Purine and Pyrimidine Metabolism
Inborn errors of purine and pyrimidine metabolism comprise essentially deficiencies or overactive enzymes. Many enzymes have isoforms, the mutations...
-
Functional mutation, splice, distribution, and divergence analysis of impactful genes associated with heart failure and other cardiovascular diseases
Cardiovascular disease (CVD) is caused by a multitude of complex and largely heritable conditions. Identifying key genes and understanding their...
-
Bridging Health Disparities: a Genomics and Transcriptomics Analysis by Race in Prostate Cancer
As the era of cancer genomics expands, disproportionate rates of prostate cancer incidence and mortality by race have demonstrated increasing...
-
PA-MSHA induces inflamed tumor microenvironment and sensitizes tumor to anti-PD-1 therapy
A low response rate to immune checkpoint inhibitor (ICI) therapy has impeded its clinical use. As reported previously, an inflamed tumor...
-
Genetics and sports performance: the present and future in the identification of talent for sports based on DNA testing
The impact of genetics on physiology and sports performance is one of the most debated research aspects in sports sciences. Nearly 200 genetic...
-
Metabolic engineering of Rhodotorula toruloides IFO0880 improves C16 and C18 fatty alcohol production from synthetic media
BackgroundThe oleaginous, carotenogenic yeast Rhodotorula toruloides has been increasingly explored as a platform organism for the production of...
-
Traceability of primordial germ cells in three neotropical fish species aiming genetic conservation actions
Primordial germ cells (PGCs) are embryonic pluripotent cells that can differentiate into spermatogonia and oogonia, and therefore, PGCs are a genetic...
-
Combination of 15q24 Microdeletion Syndrome and Metabolic Imbalance in a Patient with Atypical Autism
Autistic spectrum disorders (ASD) in children are becoming increasingly common, reaching epidemic proportions. Among the various causes contributing...
-
Origin and Evolution of RAS Membrane Targeting
KRAS , HRAS and NRAS proto-oncogenes belong to a family of 40 highly homologous genes, which in turn are a subset of a superfamily of >160 genes...
-
Evaluation of the upregulation and surface expression of hypoxanthine guanine phosphoribosyltransferase in acute lymphoblastic leukemia and Burkitt’s B cell lymphoma
BackgroundThe aim of this study is to determine whether Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) could be used as a biomarker for the...
-
Doppler ultrasonographic scan, gene expression and serum profile of immune, APPs and antioxidant markers in Egyptian buffalo–cows with clinical endometritis
The objective of this study was to elaborate Doppler ultrasonographic scan, genetic resistance and serum profile of markers associated with...
-
CDK11 regulates pre-mRNA splicing by phosphorylation of SF3B1
RNA splicing, the process of intron removal from pre-mRNA, is essential for the regulation of gene expression. It is controlled by the spliceosome, a...
-
A Systematic Review of the Genetic Predisposition to Injury in Football
PurposeSynthesise genetic association studies investigating injury involving football players to identify which genetic variants have the most...
