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Antibody-mediated neutralization of galectin-3 as a strategy for the treatment of systemic sclerosis
Systemic sclerosis (SSc) is an autoimmune, inflammatory and fibrotic disease with limited treatment options. Develo** new therapies is therefore...
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3-MCPDE in Palm Oil Processing: Formation Factors, Transference to Food and Mitigation Approaches
Palm oil is the world most produced and consumed vegetable oil. Food safetyFood safety officials have recently focused their attention on vegetable... -
H. pylori Virulence Factors: Toxins (CagA, VacA, DupA, OipA, IceA)
Helicobacter pylori (H. pylori) specifically colonizes the human stomach. The majority of bacteria live in the mucus layer overlying gastric... -
The Effect of Sintering Temperature on the Behavior of Hydroxyapatite from Different Natural Sources in Artificial Saliva
Raising pH is one of the important factors in preventing dental caries via enhancement of remineralization. This study aimed to evaluate the... -
Tumor necrosis factor alpha neutralization attenuates immune checkpoint inhibitor-induced activation of intermediate monocytes in synovial fluid mononuclear cells from patients with inflammatory arthritis
ObjectiveDuring treatment with immune checkpoint inhibitors (ICI) such as the anti-PD-1 antibody pembrolizumab, half of patients with pre-existing...
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Cardiac Effects of Micrurus corallinus and Micrurus dumerilii carinicauda (Elapidae) Venoms and Neutralization by Brazilian Coralsnake Antivenom and Varespladib
In this work, we examined the action of two South American coralsnake ( Micrurus corallinus and Micrurus dumerilii carinicauda ) venoms on rat heart...
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Risk factors and molecular epidemiology of canine rabies in Bei**g
Rabies is a serious public health problem in Asia and Africa. Approximately 99% of cases result from a bite by an infected dog. The high rabies risk...
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Factors associated with SARS-CoV-2 antibody titers and prognosis of breakthrough infection in hemodialysis patients
BackgroundThe mortality rate of Coronavirus disease 2019 (COVID-19) is extremely high in hemodialysis patients (HDP). These patients also develop...
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Klebsiella pneumoniae Virulence Factors and Biofilm Components: Synthesis, Structure, Function, and Inhibitors
Klebsiella pneumoniae is a Gram-negative pathogen capable of causing a diverse array of infections in humans. It belongs to the group of ESKAPE... -
Theileria equi claudin like apicomplexan microneme protein contains neutralization-sensitive epitopes and interacts with components of the equine erythrocyte membrane skeleton
Theileria equi is a widely distributed apicomplexan parasite that causes severe hemolytic anemia in equid species. There is currently no effective...
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Sustainability Assessment of Recycling Leaching Closed-Loop Processes for Black Shale Raffinate and Intensive Examination of Crux Factors Including Fluoride and Heavy Metals
The raffinate cycle–leaching process ensures a vanadium(V) recovery efficiency of > 86% and reduces the amount of CaF 2 by 48% (only 1.56 wt%...
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In-lake Neutralization of East German Lignite Pit Lakes: Technical History and New Approaches from LMBV
The Lausitzer und Mitteldeutsche Bergbau Verwaltungsgesellschaft (LMBV), a state-owned company, is the responsible partner for remediation of East...
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Potent antibody-mediated neutralization limits bacteriophage treatment of a pulmonary Mycobacterium abscessus infection
An 81-year-old immunocompetent patient with bronchiectasis and refractory Mycobacterium abscessus lung disease was treated for 6 months with a...
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Key factors for the survival of Lactiplantibacillus plantarum IDCC 3501 in manufacturing and storage
AbstractFunctional microbiome development has steadily increased; with this, the viability of microbial strains must be maintained not only after the...
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Employment of a high throughput functional assay to define the critical factors that influence vaccine induced cross-variant neutralizing antibodies for SARS-CoV-2
The scale and duration of neutralizing antibody responses targeting SARS-CoV-2 viral variants represents a critically important serological parameter...
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Dealkalinization Effect of Carbon Dioxide in Flue Gas on Bayer Red Mud
Red mudRed mud is a bulk solid waste generated by the aluminaAlumina industry, which is difficult to use on a large scale due to its strong... -
Effect of the Mass Fraction of Ion-Exchange Resin in a Ralex CM Cation-Exchange Membrane on Demineralization of Phenylalanine Aqueous Salt Solutions by Neutralization Dialysis
AbstractThe features of demineralization of aqueous salt solutions of phenylalanine by neutralization dialysis have been revealed, and conditions for...
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Seroprevalence of measles antibodies and factors associated with susceptibility: a national survey in Mexico using a plaque reduction neutralization test
Measles continues to be one of the leading causes of child mortality worldwide, even though a highly effective vaccine has existed for more than...
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Immunogenic and neutralization efficacy of recombinant perfringolysin O of Clostridium perfringens and its C-terminal receptor-binding domain in a murine model
Clostridium perfringens is a Gram-positive anaerobe ubiquitously present in different environments, including the gut of humans and animals. C....
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Retinal artery occlusion in young patients without typical cardiovascular risk factors: etiologies, prognosis, and suggested work-up
PurposeTo understand the etiology, work-up, and secondary systemic and ocular events of retinal artery occlusion (RAO) in young patients (≤ 45 years...