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A conserved complex lipid signature marks human muscle aging and responds to short-term exercise
Studies in preclinical models suggest that complex lipids, such as phospholipids, play a role in the regulation of longevity. However, identification...
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Physical Activity and Exercise in Diabetes During Pregnancy
Pregnancy is a good opportunity for a woman to adopt healthy living habits. Exercise during pregnancy has positive short- and long-term effects on...
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Dietary weight loss-induced improvements in metabolic function are enhanced by exercise in people with obesity and prediabetes
The additional therapeutic effects of regular exercise during a dietary weight loss program in people with obesity and prediabetes are unclear. Here,...
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Can In-Task Affect During Interval and Continuous Exercise Predict 12-Month Physical Activity Behavior? Findings from a Randomized Trial
BackgroundIn-task affective responses to moderate-intensity continuous exercise training (MICT) have been shown to predict future physical activity...
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Sirt3 mediates the benefits of exercise on bone in aged mice
Exercise in later life is important for bone health and delays the progression of osteoporotic bone loss. Osteocytes are the major bone cells...
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Effect of hypobaric hypoxia on the fiber type transition of skeletal muscle: a synergistic therapy of exercise preconditioning with a nanocurcumin formulation
Hypobaric hypoxia (HH) leads to various adverse effects on skeletal muscles, including atrophy and reduced oxidative work capacity. However, the...
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Effects of muscle fatigue on exercise-induced hamstring muscle damage: a three-armed randomized controlled trial
PurposeHamstring injuries in soccer reportedly increase towards the end of the matches’ halves as well as with increased match frequency in...
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Changes in subcutaneous adipose tissue microRNA expression in response to exercise training in African women with obesity
The mechanisms that underlie exercise-induced adaptations in adipose tissue have not been elucidated, yet, accumulating studies suggest an important...
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The effects of combined exercise training on glucose metabolism and inflammatory markers in sedentary adults: a systematic review and meta-analysis
This systematic review and meta-analysis aimed to determine the magnitude of the effect of combined exercise training on glucose metabolism markers,...
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No acute hyperglycemia induced impairment in brachial artery flow-mediated dilation before or after aerobic exercise training in young recreationally active males
There is some evidence that transient endothelial dysfunction induced by acute hyperglycemia may be attenuated by a single bout of aerobic exercise....
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Resistant Hypertension: Disease Burden and Emerging Treatment Options
Purpose of ReviewTo define resistant hypertension (RHT), review its pathophysiology and disease burden, identify barriers to effective hypertension...
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Cerebrospinal fluid metabolomes of treatment-resistant depression subtypes and ketamine response: a pilot study
Depression is a disorder with variable presentation. Selecting treatments and dose-finding is, therefore, challenging and time-consuming. In...
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Effects of Exercise on Extracellular Vesicles in Patients with Metabolic Dysfunction: a Systematic Review
The aim of this study was to investigate the effect of exercise on extracellular vesicles (EVs) in patients with metabolic dysfunction. The...
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Exercise-induced hypercalcemia and vasopressin-mediated bone resorption
SummaryOur human observational study showed that elevated arginine vasopressin levels by heavy exercise, not catecholamines, were associated with...
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Resilience and stability of the CF- intestinal and respiratory microbiome during nutritional and exercise intervention
BackgroundImpaired respiratory and intestinal microbiome composition is linked to cystic fibrosis lung disease severity. In people with cystic...
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Exercise Induced NO Modulation in Prevention and Treatment of Cardiovascular Diseases
Many aspects of modern life, including lack of physical activity, contribute to the primacy of cardiovascular disease as a cause of death worldwide....
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Understanding heterogeneity of responses to, and optimizing clinical efficacy of, exercise training in older adults: NIH NIA Workshop summary
Exercise is a cornerstone of preventive medicine and a promising strategy to intervene on the biology of aging. Variation in the response to exercise...
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Resilient or Resistant: Pandemic Crisis and Early Observations of Different Preventive Capabilities from Cumulativeness of Scientific Research Points of View
In this study, we generally postulate that there are two groups of countries that are committed to medical-related scientific and technological...
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Frailty and Treatment-Resistant Schizophrenia: A Retrospective Cohort Study
Frailty, a state of reduced physiological reserve, has not been studied in consumers with treatment-resistant schizophrenia, despite known elevated...
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A systematic review of the effect of structured exercise on inflammation and body composition in inflammatory bowel disease
PurposeGiven the substantial risk of treatment failure in inflammatory bowel disease (IBD), adjuvant therapies may play a role in disease management....
