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Paediatric sepsis-associated encephalopathy (SAE): a comprehensive review
Sepsis-associated encephalopathy (SAE) is one of the most common types of organ dysfunction without overt central nervous system (CNS) infection. It...
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Diffusion tensor imaging analysis of rheumatoid arthritis patients with neuropsychiatric features to determine the alteration of white matter integrity due to vascular events
IntroductionThe pathophysiology of neuropsychiatric manifestations in rheumatoid arthritis is not well known. The magnetic resonance imaging of the...
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Contrast-induced encephalopathy mimicking total anterior circulation stroke: a case report and review of the literature
IntroductionContrast-induced encephalopathy is a rare and usually reversible entity due to the administration of iodinated contrast. Clinical...
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Donanemab (LY3002813) Phase 1b Study in Alzheimer’s Disease: Rapid and Sustained Reduction of Brain Amyloid Measured by Florbetapir F18 Imaging
BackgroundDonanemab (LY3002813) is an IgG1 antibody directed at an N-terminal pyroglutamate of amyloid beta epitope that is present only in brain...
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Pathogenesis of acute encephalopathy in acute hepatic porphyria
Acute encephalopathy (AE) can be a manifestation of an acute porphyric attack. Clinical data were studied in 32 patients during AE with or without...
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Intracranial pressure for clinicians: it is not just a number
BackgroundInvasive intracranial pressure (ICP) monitoring is a standard practice in severe brain injury cases, where it allows to derive cerebral...
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Inhibition of Aquaporin 4 Decreases Amyloid Aβ40 Drainage Around Cerebral Vessels
Aquaporin-4 (AQP4) is located mainly in the astrocytic end-feet around cerebral blood vessels and regulates ion and water homeostasis in the brain....