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Translation and psychometric evaluation of the Persian version of “good death inventory- short Form” from the perspective of family-members of cancer patients
IntroductionAchieving good death is among the objectives of palliative care in patients with cancer. There should be an instrument for evaluating the...
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MELD-Na score may underestimate disease severity and risk of death in patients with metabolic dysfunction-associated steatotic liver disease (MASLD)
Portal hypertension often precedes the development of advanced fibrosis in patients with Metabolic dysfunction-associated steatotic liver disease...
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A novel risk prediction nomogram for early death in patients with resected synchronous multiple primary colorectal cancer based on the SEER database
BackgroundSynchronous multiple primary colorectal cancer (SMPCC) involves the simultaneous occurrence of 2 or more independent primary malignant...
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Cell Death: a Molecular Perspective
One of the vital aspects of a cell is cell death to continue their normal cell turnover, propagation, proper development, and the maintenance of the...
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A Machine Learning Computational Framework Develops a Multiple Programmed Cell Death Index for Improving Clinical Outcomes in Bladder Cancer
Comprehensive action patterns of programmed cell death (PCD) in bladder cancer (BLCA) have not yet been thoroughly investigated. Here, we collected...
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Targeting cell death pathways for cancer therapy: recent developments in necroptosis, pyroptosis, ferroptosis, and cuproptosis research
Many types of human cells self-destruct to maintain biological homeostasis and defend the body against pathogenic substances. This process, called...
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Postoperative health-related quality of life of patients with gynecological malignancy: a meta-analysis
ObjectiveWe sought to describe the short-term (1, 3, 6, 12 months) QoL changes after surgery for patients with gynecological malignancies in a...
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Cynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myeloma
The majority of blood malignancies is incurable and has unforeseeable remitting-relapsing paths in response to different treatments. Cynaropicrin, a...
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Causes of death and treatment-related mortality in newly diagnosed childhood acute lymphoblastic leukemia treatment with Chinese Children’s Cancer Group study ALL-2015
To investigate the possible risk factors for death at post-treatment in children with acute lymphoblastic leukemia (ALL). A multivariate competing...
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Immunosuppressed patients are at increased risk of local recurrence, metastasis, and disease specific death from cutaneous squamous cell carcinoma
It is well established that immunosuppressed patients are at increased risk for poor outcomes (PO) from cutaneous squamous cell carcinoma (cSCC),...
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Proton boron capture therapy (PBCT) induces cell death and mitophagy in a heterotopic glioblastoma model
Despite aggressive therapeutic regimens, glioblastoma (GBM) represents a deadly brain tumor with significant aggressiveness, radioresistance and...
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Aortic arch calcification affects causes of death in patients on hemodialysis: a retrospective cohort study
BackgroundAortic arch calcification (AAC) is a well-known risk factor for death in patients on hemodialysis (HD); however, the causes of death among...
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The Effect of Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism on the Severity and Death Rate of COVID-19 in Iranian Patients
The study was designed to assess the association of ACE I/D polymorphism with the severity and prognosis of COVID-19 in the Iranian population....
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Pan-cancer evaluation of regulated cell death to predict overall survival and immune checkpoint inhibitor response
Regulated cell death (RCD) plays a pivotal role in various biological processes, including development, tissue homeostasis, and immune response....
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Sudden Cardiac Death Risk Stratification of the Early Repolarization Syndrome: An Updated Review of the Literature
Purpose of ReviewEarly repolarization syndrome (ERS), once thought to be innocuous, has now been shown to be responsible for ventricular arrythmias...
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Association of radioactive iodine treatment in differentiated thyroid cancer and cardiovascular death: a large population-based study
PurposeThe risk of cardiovascular diseases’ death (CVD) in patients with differentiated thyroid cancer (DTC) treated with radioactive iodine (RAI)...
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Integrated machine learning survival framework develops a prognostic model based on inter-crosstalk definition of mitochondrial function and cell death patterns in a large multicenter cohort for lower-grade glioma
BackgroundLower-grade glioma (LGG) is a highly heterogeneous disease that presents challenges in accurately predicting patient prognosis....
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ARHGAP–RhoA signaling provokes homotypic adhesion-triggered cell death of metastasized diffuse-type gastric cancer
Genetic alteration of Rho GTPase-activating proteins (ARHGAP) and GTPase RhoA is a hallmark of diffuse-type gastric cancer and elucidating its...
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Effect of regulatory cell death on the occurrence and development of head and neck squamous cell carcinoma
Head and neck cancer is a malignant tumour with a high mortality rate characterized by late diagnosis, high recurrence and metastasis rates, and poor...
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A novel defined programmed cell death related gene signature for predicting the prognosis of serous ovarian cancer
PurposeThis study aims to explore the contribution of differentially expressed programmed cell death genes (DEPCDGs) to the heterogeneity of serous...
