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Chronic Kidney Disease
Congenital anomalies of kidney and the urinary tract constitute the commonest cause of chronic kidney disease (CKD) in children. The incidence and...
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Fluid homeostasis induced by sodium-glucose cotransporter 2 inhibitors: novel insight for better cardio-renal outcomes in chronic kidney disease
Hypertension in chronic kidney disease (CKD) patients is a risk factor for end-stage renal disease, cardiovascular events, and mortality. Thus, the...
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The Role of Renal Registries
Kidney disease registries are health surveillance systems that provide valuable information to inform the planning of nephrology services and to...
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Genome-wide association study of dilated cardiomyopathy-induced heart failure associated with renal insufficiency in a Chinese population
BackgroundAs it is unclear whether there is genetic susceptibility to cardiorenal syndrome (CRS), we conducted a genome-wide association study of...
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Value of multiparametric magnetic resonance imaging for evaluating chronic kidney disease and renal fibrosis
ObjectivesTo identify optimized MRI markers for evaluating chronic kidney disease (CKD) and renal interstitial fibrosis (IF).
Materials and methods ...
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Sacubitril/Valsartan in Heart Failure with Hypertension Patients: Real-World Experiences on Different Ages, Drug Doses, and Renal Functions
IntroductionHypertension is a significant risk factor in heart failure for worldwide patients. More than half of hypertensive patients suffer from...
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The influence of chronic renal insufficiency on multi-therapeutic modalities for breast cancer: a single-center experience
BackgroundDue to the presence of other comorbidities and multi-therapeutic modalities in breast cancer, renally cleared chemotherapeutic regimens may...
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Serum Cystatin C as a Risk Factor for Supratherapeutic Digoxin Concentration in Elderly Patients with Heart Failure and Chronic Kidney Disease
BackgroundDigoxin is primarily metabolized by the kidney, and its toxicity is strongly associated with high concentrations, particularly in elderly...
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Mixed cryoglobulinaemia vasculitis secondary to marginal zone lymphoma in a patient with end-stage renal failure on haemodialysis
Cryoglobulinaemia vasculitis can present with a variety of symptoms and there is limited data on the incidence and presentation of cryoglobulinaemia...
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Ultrasound dynamic monitoring of IVCD to guide application of CRRT in patients with renal failure combined with acute heart failure
We explored the application value of bedside ultrasound dynamic monitoring of the inferior vena cava diameter (IVCD) and collapse with sniff...
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Managing Heart Failure in Chronic Kidney Disease: A Review of Current Literature
Purpose of ReviewThe purpose of this review was to discuss recent literature pertaining to the management of heart failure (HF) in patients with...
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Prenatally-diagnosed renal failure: an ethical framework for decision-making
The Children’s Hospital Working Group has developed an ethical framework to guide patient care and research for prenatally diagnosed severe renal...
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Significance of reduced renal function in patients with chronic myelomonocytic leukemia
In a retrospective study, we analyzed the prevalence of increased creatinine levels in 166 patients with chronic myelomonocytic leukemia (CMML),...
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Acute-on-chronic liver failure alters linezolid pharmacokinetics in critically ill patients with continuous hemodialysis: an observational study
BackgroundIn acute-on-chronic liver failure (ACLF), adequate antibiotic dosing is challenging due to changes of drug distribution and elimination. We...
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Impact of chronic kidney disease and end-stage renal disease on the mid-term adverse outcomes in diabetic patients with cardiovascular diseases
The evidence for the impact of renal dysfunction in patients with diabetes mellitus (DM) and first cardiovascular diseases on mid-term adverse...
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Pre-existing chronic kidney disease, aetiology of acute kidney injury and infection do not affect renal outcome and mortality
BackgroundWe aimed to study the role of aetiology, pre-existing chronic kidney disease (CKD) and infections in acute kidney injury (AKI) on renal...
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PANoptosis-like death in acute-on-chronic liver failure injury
The pathogenesis of Acute-on-chronic liver failure (ACLF) involves several forms of cell death, such as pyroptosis, apoptosis, and necroptosis, which...
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Reducing the hospitalization epidemic of chronic heart failure by disease management programs
Chronic heart failure is the most common cause of hospitalization in Europe and rates are steadily increasing due to aging of the population....
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Renal Artery Stenosis
Renal artery stenosis (RAS) is the anatomic narrowing of one or more of the arteries to the kidney(s), most commonly caused by atherosclerosis. This...
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Bridging Therapies in Acute and Acute on Chronic Liver Failure
Liver failure, whether acute or acute on chronic, is a catastrophic syndrome associated with high morbidity and mortality. Liver transplantation has...