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Complete fusion of a transposon and herpesvirus created the Teratorn mobile element in medaka fish
Mobile genetic elements (e.g., transposable elements and viruses) display significant diversity with various life cycles, but how novel elements...
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The Threat from Viruses
Infectious disease represent the most significant threat to human health. Significant geologic cataclysmic events have caused the extinction of... -
Exchange of Genetic Sequences Between Viruses and Hosts
Although genetic transfer between viruses and vertebrate hosts occurs less frequently than gene flow between bacteriophages and prokaryotes, it is... -
Relapses of primary cutaneous anaplastic large-cell lymphoma in a female immunocompetent patient with persistent chlamydophila pneumoniae and human herpesvirus 8 infection
BackgroundWe have previously reported the case of an immunocompetent female patient with a primary cutaneous CD30+ anaplastic large-cell lymphoma...
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Human herpesvirus 6B reactivation and delirium are frequent and associated events after cord blood transplantation
Human herpesvirus 6B (HHV-6B) frequently reactivates after cord blood transplantation (CBT). We previously reported an association between HHV-6B...
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Human Herpesvirus 6A, 6B, 7, and 8 Infections After Hematopoietic Stem Cell Transplantation
Human herpesvirus (HHV) 6A, HHV-6B, HHV-7, and HHV-8 (also known as Kaposi’s sarcoma associated herpesvirus, or KSHV) are the most recently... -
Viral Infections in Transplant Recipients
Viruses are major opportunistic pathogens that cause significant morbidity and mortality after transplantation. They do not only cause direct... -
Dual roles for the telomeric repeats in chromosomally integrated human herpesvirus-6
Approximately 1 percent of healthy individuals carry human herpesvirus-6 within a host chromosome. This is referred to as chromosomally integrated...
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Human herpesvirus-6 encephalitis after allogeneic hematopoietic cell transplantation: What we do and do not know
Human herpesvirus-6 (HHV-6) encephalitis following allogeneic hematopoietic cell transplantation is a serious and often fatal complication...
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The Future of Digital Polymerase Chain Reaction in Virology
Driven by its potential benefits over currently available methods, and the recent development of commercial platforms, digital polymerase chain...
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Hepatobiliary Infections After Solid Organ or Hematopoietic Cell Transplantation
Liver and biliary tract infections are common after solid organ (SOT) or hematopoietic cell transplantation (HCT). SOT recipients who receive liver... -
Viral Genomic Insertions in the Host Cell’s Genome
“Retroviruses R Us”: the retroviral inheritance of the human race. “Retroviruses R Us” was the title of the author’s presentation given at the Kaposi... -
Epigenetic Alterations in Epstein-Barr Virus-Associated Diseases
Latent Epstein-Bar virus genomes undergo epigenetic modifications which are dependent on the respective tissue type and cellular phenotype. These... -
Investigation of Human Cancers for Retrovirus by Low-Stringency Target Enrichment and High-Throughput Sequencing
Although nearly one fifth of all human cancers have an infectious aetiology, the causes for the majority of cancers remain unexplained. Despite the...
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A case of bilateral human herpes virus 6 panuveitis with genomic viral DNA integration
BackgroundWe report a rare case of bilateral panuveitis from human herpes virus 6 (HHV-6) with genomic viral DNA integration in an immunocompromised...
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Human Herpesviruses: Human Herpesvirus 6
A snapshot of human herpesvirus 6 (HHV-6) reveals several key features of this virus that are clearly established. HHV-6 causes ubiquitous infection... -
The Role of Viruses in the Genesis of Hodgkin Lymphoma
Hodgkin lymphoma (HL) is a heterogeneous condition. Seminal papers published in 1957 and 1966 suggested that HL in younger and older adults had... -
Viral Infections of the Nervous System
Encephalitides with a known etiology account for 30–60 % of the total, and viruses are their most frequent cause in immunocompetent individuals....