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P-TarPmiR accurately predicts plant-specific miRNA targets
microRNAs (miRNAs) are small non-coding ribonucleic acids that post-transcriptionally regulate gene expression through the targeting of messenger RNA...
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miRNA-200c-3p deficiency promotes epithelial-mesenchymal transition in triple-negative breast cancer by activating CRKL expression
Epithelial-mesenchymal transition (EMT) plays an important role in malignant progression of Triple-negative breast cancer (TNBC). Many studies have...
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Comparison of miRNA transcriptome of exosomes in three categories of somatic cells with derived iPSCs
Somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) through epigenetic manipulation. While the essential role of miRNA in...
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miRNA-seq analysis of high glucose induced osteoblasts provides insight into the mechanism underlying diabetic osteoporosis
The present study aims to explore the etiology of Diabetic osteoporosis (DOP), a chronic complication associated with diabetes mellitus....
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Interaction between HOTTIP, H19, and HOTAIR long noncoding RNAs and miRNA-152 in cases of HCC caused by HCV infection
BackgroundLiver cancer (hepatocellular carcinoma “HCC”) remains a significant health issue without prompt detection and appropriate prevention. By...
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miRNA as biomarker in lung cancer
Lung cancer has a high prevalence and mortality due to its late diagnosis and limited treatment, so it is essential to find biomarkers that allow a...
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Recent miRNA Research in Asthma
Purpose of ReviewThe study of microRNA in asthma has revealed a vibrant new level of gene regulation underlying asthma pathology. Several miRNAs have...
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Multifunctional elastin-like polypeptide nanocarriers for efficient miRNA delivery in cancer therapy
BackgroundThe exogenous delivery of miRNA to mimic and restore miRNA-34a activity in various cancer models holds significant promise in cancer...
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Evaluation of miRNA-16–2-3P, miRNA-618 levels and their diagnostic and prognostic value in the regulation of immune response during SARS Cov-2 infection
Following the announcement of the pandemic of COVID-19 in December 2019, several studies focused on how to early predict the severity of the disease...
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Recent trends in miRNA therapeutics and the application of plant miRNA for prevention and treatment of human diseases
BackgroundResearchers now have a new avenue to investigate when it comes to miRNA-based therapeutics. miRNAs have the potential to be valuable...
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Integrative network analysis of miRNA-mRNA expression profiles during epileptogenesis in rats reveals therapeutic targets after emergence of first spontaneous seizure
Epileptogenesis is the process by which a normal brain becomes hyperexcitable and capable of generating spontaneous recurrent seizures. The extensive...
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Preliminary study on miRNA in prostate cancer
ObjectiveTo screen for miRNAs differentially expressed in prostate cancer and prostate hyperplasia tissues and to validate their association with...
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mRNA–miRNA bipartite networks reconstruction in different tissues of bladder cancer based on gene co-expression network analysis
Bladder cancer (BC) is one of the most important cancers worldwide, and if it is diagnosed early, its progression in humans can be prevented and...
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MiRNA-93: a novel signature in human disorders and drug resistance
miRNA-93 is a member of the miR-106b-25 family and is encoded by a gene on chromosome 7q22.1. They play a role in the etiology of various diseases,...
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Effects of nitrogen deficiency and drought stresses on miRNA expressions in Arabidopsis thaliana
MicroRNAs are now known to have an important role in regulating gene expression of eukaryotic organisms. miRNA research in plants gained importance...
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Comprehensive analysis of miRNA profiling in Schistosoma mekongi across life cycle stages
Schistosoma mekongi , a significant schistosome parasite, has various life stages, including egg, cercaria, female, and male, that play crucial roles...
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Preparation and Characterization of pH-Responsive Charge Reversal Nanocomposite for miRNA Delivery
pH-responsive charge reversal loaded miRNA nanocomposite was prepared by electrostatic self-assembly. The morphology, particle size and zeta...
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Intra-articular injection of miRNA-1 agomir, a novel chemically modified miRNA agonists alleviates osteoarthritis (OA) progression by downregulating Indian hedgehog in rats
Our objective in this study is to determine whether intra-articular injection of miRNA-1 can attenuate the progression of OA in rats by down...
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Identification of miRNA expression profile in middle ear cholesteatoma using small RNA-sequencing
BackgroundThe present study aims to identify the differential miRNA expression profile in middle ear cholesteatoma and explore their potential roles...
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Trimethylamine-N-oxide, a New Risk Factor for Non-alcoholic Fatty Liver Disease Changes the Expression of miRNA-34a, and miRNA-122 in the Fatty Liver Cell Model
Non-alcoholic fatty liver disease is a multifactorial disorder with complicated pathophysiology ranging from simple steatosis to steatohepatitis and...
