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Long non-coding RNA SLC25A21-AS1 inhibits the development of epithelial ovarian cancer by specifically inducing PTBP3 degradation
BackgroundEpithelial ovarian cancer (EOC) is a highly prevalent disease that rapidly metastasizes and has poor prognosis. Most women are in the...
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Ovarian tissue cryopreservation for fertility preservation before hematopoietic stem cell transplantation in patients with sickle cell disease: safety, ovarian function follow-up, and results of ovarian tissue transplantation
PurposeTo describe the experience of performing ovarian tissue cryopreservation (OTC) before hematopoietic stem cell transplantation (HSCT), among...
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Role of miRNAs interference on ovarian functions and premature ovarian failure
Premature ovarian failure is a to some extent unknown and intricate problem with diverse causes and clinical manifestations. The lack of ovarian sex...
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Artificial Intelligence in Ovarian Digital Pathology
As one of the leading technological advances in histopathology in recent years, digital pathology and the move towards fully digitised workflows is...
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Heterogeneity and treatment landscape of ovarian carcinoma
Ovarian carcinoma is characterized by heterogeneity at the molecular, cellular and anatomical levels, both spatially and temporally. This...
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Polycystic Ovarian Syndrome (PCOS)
Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. Its clinical presentation includes oligo- or...
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Mitochondrial Quality Control in Ovarian Function: From Mechanisms to Therapeutic Strategies
Mitochondrial quality control plays a critical role in cytogenetic development by regulating various cell-death pathways and modulating the release...
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Chronic Fluoride Exposure Induces Ovarian Dysfunction and Potential Association with Premature Ovarian Failure in Female Rats
Chronic fluorosis has been widely investigated for its adverse effects on skeletal and neurological health; however, its impact on reproductive...
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Patient-Derived Xenograft Models for Ovarian Cancer
Patient-derived xenograft (PDX) models play a crucial role for in vivo research. They maintain the original molecular characteristics of the human...
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Molecular Pathology of Ovarian Tumors
Ovarian cancer is associated with high morbidity and mortality and is the leading cause of gynecologic cancer-related death in the US. In recent...
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Ovarian Transposition
Iatrogenic premature ovarian failure is one of severe complications of oncological treatment, leading to early menopause and infertility, especially...
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Premature Ovarian Insufficiency
Genetic and environmental factors influence the quality of life and well-being. Breaking of adaptive mechanisms, induced by stressors, triggers...
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LncRNA GAS5-hnRNPK axis inhibited ovarian cancer progression via inhibition of AKT signaling in ovarian cancer cells
BackgroundThe incidence of ovarian cancer ranks third among gynecologic malignancies, but the mortality rate ranks first.
MethodsThe expression of...
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Long-term effect of chemotherapy after ovarian decortication on the ovarian function in women surviving cancer
PurposeOvarian decortication may affect ovarian function. We investigated the status of ovarian reserve after ovarian decortication plus chemotherapy...
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Development and characterization of Spodoptera mauritia ovarian primary cell culture and evaluation of fenoxycarb toxicity
The rice swarming caterpillar, Spodoptera mauritia (Biosduval, 1833) (Lepidoptera: Noctuidae), has been considered a severe pest and has caused the...
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Human mesenchymal stem cells derived exosomes improve ovarian function in chemotherapy-induced premature ovarian insufficiency mice by inhibiting ferroptosis through Nrf2/GPX4 pathway
BackgroundChemotherapy exposure has become a main cause of premature ovarian insufficiency (POI). This study aimed to evaluate the role and molecular...
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The emerging roles of miRNA-mediated autophagy in ovarian cancer
Ovarian cancer is one of the common tumors of the female reproductive organs. It has a high mortality rate, is highly heterogeneous, and early...
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Therapy-Associated Ovarian Damage and its Management Strategies
Iatrogenic ovarian injuries are impairments to ovarian function caused by surgery, radiotherapy, and chemotherapy drugs. With medical improvements,...
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Histone methyltransferase SETD1A interacts with notch and promotes notch transactivation to augment ovarian cancer development
BackgroundHigh expression of SETD1A, a histone methyltransferase that specifically methylates H3K4, acted as a key oncogene in several human cancers....
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Effect of intra-ovarian injection of platelet-rich plasma on the patients with a poor ovarian response (POR) or premature ovarian insufficiency (POI): a systematic review and meta-analysis
BackgroundPOR or POI poses a significant challenge to fertility treatment with different ovarian stimulation strategies. Intra-ovarian injection of...
