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NLRP7 variants in spontaneous abortions with multilocus imprinting disturbances from women with recurrent pregnancy loss
PurposeComparative analysis of multilocus imprinting disturbances (MLIDs) in miscarriages from women with sporadic (SPL) and recurrent pregnancy loss...
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Seed tuber imprinting shapes the next-generation potato microbiome
BackgroundPotato seed tubers are colonized and inhabited by soil-borne microbes, that can affect the performance of the emerging daughter plant in...
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Fabrication of large-scale infrared diffractive lens arrays on chalcogenide glass by means of step-and-repeat hot imprinting and non-isothermal glass molding
In this study, a new cost-effective and high-precision process chain for the fabrication of large-scale infrared (IR) diffractive lens arrays on...
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Molecularly imprinted polymers by epitope imprinting: a journey from molecular interactions to the available bioinformatics resources to scout for epitope templates
The molecular imprinting of proteins is the process of forming biomimetics with entailed protein-recognition by means of a template-assisted...
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Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE
Resident-tissue macrophages (RTMs) arise from embryonic precursors
1 ,2 , yet the developmental signals that shape their longevity remain largely... -
Neural pathways of olfactory kin imprinting and kin recognition in zebrafish
Teleost fish exhibit extraordinary cognitive skills that are comparable to those of mammals and birds. Kin recognition based on olfactory and visual...
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Reproductive technologies, female infertility, and the risk of imprinting-related disorders
BackgroundEpidemiological studies suggest that singletons born from assisted reproductive technologies (ART) have a high risk of adverse perinatal...
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Marsupials have monoallelic MEST expression with a conserved antisense lncRNA but MEST is not imprinted
The imprinted isoform of the Mest gene in mice is involved in key mammalian traits such as placental and fetal growth, maternal care and mammary...
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Prenatal diagnosis of fetuses with region of homozygosity detected by single nucleotide polymorphism array: a retrospective cohort study
Region of homozygosity (ROH) is classified as uniparental disomy (UPD) or identity by descent, depending on its origin. To explore the clinical...
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DNA methylation of imprint control regions associated with Alzheimer’s disease in non-Hispanic Blacks and non-Hispanic Whites
Alzheimer’s disease (AD) prevalence is twice as high in non-Hispanic Blacks (NHBs) as in non-Hispanic Whites (NHWs). The objective of this study was...
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A novel imprinted locus on bovine chromosome 18 homologous with human chromosome 16q24.1
Genomic imprinting is an epigenetic regulation mechanism in mammals resulting in the parentally dependent monoallelic expression of genes. Imprinting...
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Does tissue imprinting restrict macrophage plasticity?
Macrophages have long been considered as particularly plastic cells. However, recent work combining fate map**, single-cell transcriptomics and...
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DNA Methylation as a Biomarker and Application to Aluminum: ADRB2 5′-Untranslated Region (5′-UTR) Methylation Level
Environmental heavy metal exposure might be considered as a contributor to childhood asthma development and its levels of control. Moreover, heavy... -
Discovering candidate imprinted genes and imprinting control regions in the human genome
BackgroundGenomic imprinting is a process thereby a subset of genes is expressed in a parent-of-origin specific manner. This evolutionary novelty is...
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In vivo inhibition of nuclear ACE2 translocation protects against SARS-CoV-2 replication and lung damage through epigenetic imprinting
In vitro, ACE2 translocates to the nucleus to induce SARS-CoV-2 replication. Here, using digital spatial profiling of lung tissues from...
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Unusual deletion of the maternal 11p15 allele in Beckwith–Wiedemann syndrome with an impact on both imprinting domains
BackgroundWhereas duplications in 11p15.5 covering both imprinting centers (ICs) and their subordinated genes account for up to 1% of...
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Epigenetic control of chromosome-associated lncRNA genes essential for replication and stability
ASARs are long noncoding RNA genes that control replication timing of entire human chromosomes in cis. The three known ASAR genes are located on...
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Identification of differentially methylated regions in rare diseases from a single-patient perspective
BackgroundDNA methylation (5-mC) is being widely recognized as an alternative in the detection of sequence variants in the diagnosis of some rare...
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Relationships between UBE3A and SNORD116 expression and features of autism in chromosome 15 imprinting disorders
Chromosome 15 (C15) imprinting disorders including Prader–Willi (PWS), Angelman (AS) and chromosome 15 duplication (Dup15q) syndromes are severe...
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Hydrophobic Aluminum Alloy Surfaces Fabricated by Imprinting Process and Their Wetting State Evaluation Using Air Layer Images
This paper presents an imprinting process, which can impart hydrophobicity to aluminum alloy surfaces, and a method for analyzing the wetting states...