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Immunoglobulin G4-related disease presenting with nephrotic syndrome due to minimal change disease: a case report
BackgroundImmunoglobulin G4-related disease is an inflammatory disease affecting multiple organs including the kidney. Immunoglobulin G4-related...
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Procedural Steps
Adequate day of case preparation for the TADV procedure is a crucial element for success throughout each procedural step. The initial step involves...
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A case of paraneoplastic IgA nephropathy with glomerular capillary IgA and galactose-deficient IgA1 deposition
Paraneoplastic IgA nephropathy (IgAN) is an underrecognized condition in which malignancy manifests as symptoms of IgAN, and it remains controversial...
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Electron Microscopy of Minimal Change Disease
Minimal change disease (MCD) is a glomerular disorder characterized by a lack of discernible glomerular pathology on light microscopy but abnormal...
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Impact of kidney biopsy on deciding when to initiate enzyme replacement therapy in children with Fabry disease
BackgroundRecommendations on when to start enzyme replacement therapy (ERT) in children with Fabry disease (FD) differ between guidelines. In this...
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Concurrent glomerular PCDH7 deposits in PLA2R-associated membranous nephropathy
The understanding of membranous nephropathy (MN) has undergone impressive advancements in the last 5 years, particularly due to identification of...
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IgA nephropathy in a boy with frequently relapsing nephrotic syndrome
A Japanese boy developed nephrotic syndrome (NS) and had microscopic hematuria at 8 years old. Renal biopsy was performed. Light microscopy study...
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Electron Microscopy of IgA Nephropathy
This chapter will give an overview of the clinical and pathological features of IgA nephropathy, followed by a detailed, illustrated description of...
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Clinicopathological characteristics of pediatric ANCA-associated glomerulonephritis
BackgroundAnti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis and glomerulonephritis is uncommon in children. We sought to characterize...
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Knockdown of USF2 inhibits pyroptosis of podocytes and attenuates kidney injury in lupus nephritis
As an essential factor in the prognosis of Systemic lupus erythematosus (SLE), lupus nephritis (LN) can accelerate the rate at which patients with...
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Clinicopathological characteristics and outcomes of lupus nephritis patients with scanty immune depositions in kidney biopsies
BackgroundThe clinicopathological features, outcomes, and pathogenesis of lupus nephritis with scanty immune deposits in the kidney biopsy remain...
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A case of long-term dasatinib-induced proteinuria and glomerular injury
A 52-year-old woman was diagnosed with chronic myeloid leukemia. Treatment with dasatinib, a second-generation Bcr–Abl tyrosine kinase inhibitor, was...
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Assessment of single and combined administration of ubiquinone and lactoferrin on histopathology, ultrastructure, oxidative stress, and WNT4 expression gene induced by thioacetamide on hepatorenal system of adult male rats
BackgroundHepatorenal syndrome is a life-threatening medical complication of liver cirrhosis. Hepatic cirrhosis is commonly accompanied by rapid...
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Electron Microscopy of IgM and C1q Glomerulopathies
This chapter will give an overview of the clinical and pathological features of IgM nephropathy and C1q nephropathy, followed by a detailed,...
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Single and Combined Effects of Short-Term Selenium Deficiency and T-2 Toxin-Induced Kidney Pathological Injury Through the MMPs/TIMPs System
The single and combined effects of short-term selenium (Se) deficiency and T-2 toxin-induced kidney pathological injury through the MMPs/TIMPs system...
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Spectrum of podocytopathies in new-onset nephrotic syndrome following COVID-19 disease: a report of 2 cases
BackgroundCoronavirus disease-2019 (COVID-19) is an ongoing pandemic which has affected over 12 million people across the globe. Manifestations in...
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Dyslipidemia and Diabetes
Diabetic kidney disease (DKD) is a severe kidney-related complication of type 1 diabetes and type 2 diabetes, which develops in approximately 30% of...
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A rare case of nephrotic syndrome associated with Dent’s disease: a case report
Dent’s disease is a rare X-linked condition caused by a mutation in CLCN5 and OCRL gene, which impair the megalin-cubilin receptor-mediated...
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Mild mesangial proliferative IgA nephropathy with and without minimal change disease
Mild mesangial proliferative IgA nephropathy with minimal change disease (MCD-IgAN) and mild mesangial proliferative IgA nephropathy without minimal...
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