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Validity of serum neurofilament light chain as a prognostic biomarker of disease activity in multiple sclerosis
Multiple sclerosis (MS) is a chronic demyelinating and neuroinflammatory disease of the human central nervous system with complex pathoetiology,...
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Tertiary lymphoid structures as a potential prognostic biomarker for combined hepatocellular–cholangiocarcinoma
BackgroundCombined hepatocellular–cholangiocarcinoma (cHCC–CCA), as a rare primary hepatic tumor, is challenging to accurately assess in terms of the...
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Novel biomarker SARIFA in colorectal cancer: highly prognostic, not genetically driven and histologic indicator of a distinct tumor biology
SARIFA (Stroma AReactive Invasion Front Areas) has recently emerged as a promising histopathological biomarker for colon and gastric cancer. To...
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Low expression of PRRG2 in kidney renal clear cell carcinoma: an immune infiltration-associated prognostic biomarker
ObjectiveThis study aims to explore the prognostic significance of Proline-rich γ-carboxyglutamic acid protein 2 (PRRG2) in Kidney Renal Clear Cell...
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Prognostic biomarker tumor-infiltrating lymphocytes failed to serve as a predictive biomarker for postoperative radiotherapy in completely resected pN2 non-small cell lung cancer: a retrospective analysis
BackgroundEvidence suggests that radiotherapy is a potent immunomodulator in non-small cell lung cancer (NSCLC). Conversely, it has rarely been...
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Long non-coding RNA LINC-PINT as a novel prognostic biomarker in human cancer: a meta-analysis and machine learning
Long intergenic non-protein coding RNA, P53 induced transcript (LINC-PINT) exhibits different expression patterns in the majority of tumors, yet its...
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GBP2 is a prognostic biomarker and associated with immunotherapeutic responses in gastric cancer
BackgroundThe interferon-induced protein known as guanylate-binding protein 2 (GBP2) has been linked to multiple different cancer types as an...
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Comprehensive analysis of KLF2 as a prognostic biomarker associated with fibrosis and immune infiltration in advanced hepatocellular carcinoma
PurposeMost Hepatocellular carcinoma (HCC) patients are in advanced or metastatic stage at the time of diagnosis. Prognosis for advanced HCC patients...
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Frontal lobe fALFF measured from resting-state fMRI as a prognostic biomarker in first-episode psychosis
Clinical response to antipsychotic drug treatment is highly variable, yet prognostic biomarkers are lacking. The goal of the present study was to...
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Prognostic Imaging Biomarker Discovery in Survival Analysis for Idiopathic Pulmonary Fibrosis
Imaging biomarkers derived from medical images play an important role in diagnosis, prognosis, and therapy response assessment. Develo** prognostic... -
ARHGAP39 is a prognostic biomarker involved in immune infiltration in breast cancer
BackgroundCurrent studies on the role of ARHGAP39 mainly focused on its effect on neurodevelopment. However, there are few studies on the...
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Cuproptosis-related gene SERPINE1 is a prognostic biomarker and correlated with immune infiltrates in gastric cancer
PurposeThe serine protease inhibitor clade E member 1 (SERPINE1) has been studied as a potential biomarker in a variety of cancers, but poorly...
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CXCL10 could be a prognostic and immunological biomarker in bladder cancer
IntroductionAs proteins that promote immune cell differentiation, chemokines have attracted great interest regarding their role in anti-tumor immune...
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TREM-1 as a potential prognostic biomarker associated with immune infiltration in clear cell renal cell carcinoma
BackgroundThe tumor immune microenvironment plays a crucial role in the efficacy of various therapeutics. However, their correlation is not yet...
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HOXD9 is a potential prognostic biomarker involved in immune microenvironment of glioma
BackgroundGlioma is the prevailing malignant tumor affecting the brain and central nervous system, constituting over 80% of all malignant brain...
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Comprehensive analysis of BTNL9 as a prognostic biomarker correlated with immune infiltrations in thyroid cancer
BackgroundThyroid cancer (THCA) is the most common type of endocrine cancers, and the disease recurrences were usually associated with the risks of...
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Identification of novel therapeutic target and prognostic biomarker in matrix metalloproteinase gene family in pancreatic cancer
Matrix metalloproteinases (MMPs) play an essential role in various physiological events. Recent studies have revealed its carcinogenic effect in...
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ITGB4 is a prognostic biomarker and correlated with lung adenocarcinoma brain metastasis
BackgroundThe aim of this study is to explore the prognostic value and immune signature of ITGB4 expression in lung adenocarcinoma (LUAD) brain...
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APOC1 is a prognostic biomarker associated with M2 macrophages in ovarian cancer
BackgroundRecent studies have demonstrated that APOC1 is associated with cancer progression, exerting cancer-promoting and immune...
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PKM2 is a potential prognostic biomarker and related to immune infiltration in lung cancer
Pyruvate kinase M2 ( PKM2 ), a subtype of pyruvate kinase, plays a crucial role as a key enzyme in the final step of glycolysis. It is involved in...