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Progestin-related WHO grade II meningiomas behavior—a single-institution comparative case series
WHO grade II progestin-related meningiomas have been reported in recent series but we found no previous study describing their long-term outcome. Our...
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Efficacy of radiotherapy and stereotactic radiosurgery as adjuvant or salvage treatment in atypical and anaplastic (WHO grade II and III) meningiomas: a systematic review and meta-analysis
The role of radiotherapy (RT) and stereotactic radiosurgery (SRS) as adjuvant or salvage treatment in high-grade meningiomas (HGM) is still debated....
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Second Grade—Fables
Learning objectives focused on second grade literacy are based on national and international standards and are provided in a grid format. Objectives... -
Multisession radiosurgery for grade 2 (WHO), high risk meningiomas. A phase II clinical trial
PurposePatients suffering from recurrent and residual grade 2 (WHO) meningiomas after subtotal excision should be considered as high-risk groups with...
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Fourth Grade—Legends
Learning objectives focused on fourth grade literacy are based on national and international standards and are provided in a grid format. Objectives... -
Fifth Grade—Myths
Learning objectives focused on fifth grade literacy are based on national and international standards and are provided in a grid format. Objectives... -
Pancreatic Neuroendocrine Microtumors (WHO 2022) Are Not Always Low-Grade Neoplasms: A Case with a Highly Increased Proliferation Rate
Traditionally considered non-functional low proliferative benign neuroendocrine proliferations measuring less than 5 mm, pancreatic (neuro)endocrine...
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The prognostic power of [11C]methionine PET in IDH-wildtype diffuse gliomas with lower-grade histological features: venturing beyond WHO classification
PurposeIDH-wildtype (IDH-wt) diffuse gliomas with histological features of lower-grade gliomas (LGGs) are rare and heterogeneous primary brain...
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Clinical characteristics and radiological features of glioblastoma, IDH-wildtype, grade 4 with histologically lower-grade gliomas
The 2021 World Health Organization (WHO) classification of central nervous system tumors applied molecular criteria and further integrated...
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Genetic Discrimination of Grade 3 and Grade 4 Gliomas by Artificial Neural Network
Gliomas, including anaplastic gliomas (AG; grade 3) and glioblastomas (GBM; grade 4), are malignant brain tumors associated with poor prognosis and...
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A large-scale targeted proteomics of serum and tissue shows the utility of classifying high grade and low grade meningioma tumors
BackgroundMeningiomas are the most prevalent primary brain tumors. Due to their increasing burden on healthcare, meningiomas have become a pivot of...
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High-Grade B-Cell Lymphomas
High-grade B-cell lymphomas (HGBL) are particularly aggressive tumors with poor clinical outcomes. Introduced in the 4th Revised WHO in 2016, this... -
Development and validation of clinical-radiomics analysis for preoperative prediction of IDH mutation status and WHO grade in diffuse gliomas: a consecutive l-[methyl-11C] methionine cohort study with two PET scanners
PurposeDetermination of isocitrate dehydrogenase ( IDH ) genotype is crucial in the stratification of diagnosis and prognostication in diffuse...
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Male sex and presence of preoperative symptoms are associated with early recurrence of WHO grade I meningiomas after surgical resection: analysis from the nationwide Brain Tumor Registry of Japan
This study aimed to assess the risk factors for the recurrence of WHO grade I intracranial meningiomas using the Brain Tumor Registry of Japan (BTRJ)...
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SEOM-GEINO clinical guidelines for grade 2 gliomas (2023)
The 2021 World Health Organization (WHO) classification has updated the definition of grade 2 gliomas and the presence of isocitrate dehydrogenase...
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First Grade—Fairy Tales
Learning objectives focused on first grade literacy are based on national and international standards and are provided in a grid format. Objectives... -
Gender gaps in grades versus grade penalties: why grade anomalies may be more detrimental for women aspiring for careers in biological sciences
BackgroundIn the US, bioscience programs now often have more women than men who earn degrees at all levels. Despite this, evidence still exists for...
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Clinicopathologic features and prognostic significance of mixed (Low and high-grade) papillary urothelial carcinoma comparison with low and high-grade papillary urothelial carcinoma
The World Health Organization/International Society of Urological Pathology (2022 WHO/ISUP) classification categorizes noninvasive carcinomas based...
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Physical Prehabilitation in Patients who Underwent Major Abdominal Surgery: A Comprehensive Systematic Review and Component Network Meta-Analysis Using GRADE and CINeMA Approach
BackgroundPhysical prehabilitation is recommended before major abdominal surgery to ameliorate short-term outcomes.
MethodsA frequentist,...
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Radiotherapy for pediatric low-grade glioma
IntroductionRadiotherapy is a highly effective treatment for pediatric low-grade glioma, serving as the standard for evaluating progression-free and...