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Membrane fusion reverse micelle platforms as potential oral nanocarriers for efficient internalization of free hydrophilic peptides
Orally administered peptides or proteins are garnering increasing preference owing to their superiority in terms of patient compliance and...
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Adipositastherapie – werden Pharmakotherapien die Alternative zur metabolischen Chirurgie sein?
Obesity is a chronically progressing disease that represents a major challenge for affected patients, health care professionals and society, since it...
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Therapeutic Peptides and Proteins: Stabilization Challenges and Biomedical Applications by Means of Nanodelivery Systems
The delivery of peptides and proteins usually faces formulation development challenges attributed to the difficulties encountered in their...
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Therapeutic Peptide Delivery: Fundamentals, Formulations, and Recent Advances
Recent advances in the field of peptide therapeutics have led to the design and synthesis of many promising peptides. However, research and...
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Obesity: A Disease of Overnutrition
Obesity is a serious worldwide problem that is increasing in prevalence. Obesity results from increased energy intake from food exceeding what is...
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Effect of Swallow Balloon Therapy with the Combination of Semaglutide Oral Formulation: a Randomised Double-Blind Single-Centre Study
BackgroundObesity is a significant public health issue; new therapies and pharmaceutical approaches to weight management are needed.
Objective ...
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Adipositastherapie – werden Pharmakotherapien die Alternative zur metabolischen Chirurgie sein?
Obesity is a chronically progressing disease that represents a major challenge for affected patients, health care professionals and society, since it...
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Injektionstherapie (GLP1-Rezeptor Agonisten und Insulin) bei Typ 2 Diabetes mellitus (Update 2023)
The present article is a recommendation of the Austrian Diabetes Association for the practical use of injection therapy (GLP1-receptor agonists and...
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The evolution of commercial drug delivery technologies
Drug delivery technologies have enabled the development of many pharmaceutical products that improve patient health by enhancing the delivery of a...
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Peptide permeation enhancers for improving oral bioavailability of macromolecules
BackgroundOral delivery of macromolecules has been limited mainly by their low intestinal permeability. Chemical permeation enhancers (CPEs) are...
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Post-Transplant Diabetes Mellitus
Post-transplant diabetes mellitus (PTDM) is one of the important metabolic complications occurring in about 10–20% of the patients following kidney...
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The Thyroid Pathologist Meets Therapeutic Pharmacology
The effects of many pharmacological agents on thyroid function are well known. Direct influences on measurements of thyroid function tests are also...
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Pediatric Ambulatory Surgery: What’s New, What’s Controversial
Purpose of ReviewThis article aims to review recent innovations and trends in ambulatory anesthesia through the lens of the pediatric ambulatory...
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Challenges and Opportunities in the Delivery of Oral Anticancer Therapeutics
Global cancer prevalence has continuously increased in the last decades despite substantial progress achieved for patient care. Cancer is no longer...
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Identification of a Multi-Component Formulation for Intestinal Delivery of a GLP-1/Glucagon Co-agonist Peptide
PurposeOral delivery of therapeutic peptides has been challenging due to multiple physiological factors and physicochemical properties of peptides....
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Drug shortages in Israel, revisited: a bitter pill to swallow
BackgroundIn 2017, we published an article addressing drug shortages (DS) in Israel, exploring regulatory perspectives, challenges, and potential...
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The effect of semaglutide on blood pressure in patients with type-2 diabetes: a systematic review and meta-analysis
ObjectiveTo evaluate the blood pressure (BP) lowering ability of semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1 RA), in individuals...
