Search
Search Results
-
Metabolic profiling of patients with different idiopathic inflammatory myopathy subtypes reveals potential biomarkers in plasma
Idiopathic inflammatory myopathy (IIM) are heterogeneous autoimmune diseases that primarily affect the proximal muscles. IIM subtypes include...
-
The sex-specific metabolic signature of C57BL/6NRj mice during aging
Due to intact reactive oxygen species homeostasis and glucose metabolism, C57BL/6NRj mice are especially suitable to study cellular alterations in...
-
AnimalTraits - a curated animal trait database for body mass, metabolic rate and brain size
Trait databases have become important resources for large-scale comparative studies in ecology and evolution. Here we introduce the AnimalTraits...
-
Metabolic Evidence on Vintage Effect in Tea (Camellia sinensis L.) Plants
Recent metabolomics studies have reported diverse metabolites of tea depending on tea ( Camellia sinensis ) cultivars, cultivation conditions and...
-
Probabilistic quotient’s work and pharmacokinetics’ contribution: countering size effect in metabolic time series measurements
Metabolomic time course analyses of biofluids are highly relevant for clinical diagnostics. However, many sampling methods suffer from unknown sample...
-
City comfort: weaker metabolic response to changes in ambient temperature in urban red squirrels
The ecophysiological responses of species to urbanisation reveal important information regarding the processes of successful urban colonization and...
-
The role of empagliflozin-induced metabolic changes for cardiac function in patients with type 2 diabetes. A randomized cross-over magnetic resonance imaging study with insulin as comparator
BackgroundMetabolic effects of empagliflozin treatment include lowered glucose and insulin concentrations, elevated free fatty acids and ketone...
-
CanB is a metabolic mediator of antibiotic resistance in Neisseria gonorrhoeae
The evolution of the obligate human pathogen Neisseria gonorrhoeae has been shaped by selective pressures from diverse host niche environments and...
-
Timing matters: diurnal variation of maximal fat oxidation and substrate oxidation rates in metabolic syndrome—a randomized crossover study
PurposeThe aim of this study was to investigate if diurnal oscillation in maximal fat oxidation (MFO) and substrate oxidation rates during exercise...
-
Microstructural and Metabolic Changes in Normal Aging Human Brain Studied with Combined Whole-Brain MR Spectroscopic Imaging and Quantitative MR Imaging
PurposeThis study aimed to detect age-related brain metabolic and microstructural changes in healthy human brains by the use of whole-brain proton...
-
Light/dark phase influences intra-individual plasticity in maintenance metabolic rate and exploratory behavior independently in the Asiatic toad
BackgroundIt is well-known that light/dark phase can affect energy expenditure and behaviors of most organisms; however, its influences on...
-
Systems biology of plant metabolic interactions
Metabolism is the key cellular process of plant physiology. Understanding metabolism and its dynamical behavior under different conditions may help...
-
Potential metabolic biomarkers of critical limb ischemia in people with type 2 diabetes mellitus
IntroductionType 2 diabetes mellitus (T2DM) is a significant risk factor for the development of critical limb ischemia (CLI), the most advanced stage...
-
Exercise derived myokine irisin as mediator of cardiorespiratory, metabolic and thermal adjustments during central and peripheral chemoreflex activation
Exercise elicits physiological adaptations, including hyperpnea. However, the mechanisms underlying exercise-induced hyperpnea remain unresolved....
-
Dynamic metabolic changes measured by indirect calorimetry during the early phase of septic shock: a prospective observational pilot study
Background and aimsEnergy metabolism (energy deficit, substrate consumption) in the early phase of septic shock is not clearly understood. The...
-
Characterizing the metabolic effects of the selective inhibition of gut microbial β-glucuronidases in mice
The hydrolysis of xenobiotic glucuronides by gut bacterial glucuronidases reactivates previously detoxified compounds resulting in severe gut...
-
Cataloging the potential SNPs (single nucleotide polymorphisms) associated with quantitative traits, viz. BMI (body mass index), IQ (intelligence quotient) and BP (blood pressure): an updated review
BackgroundSingle nucleotide polymorphism (SNP) variants are abundant, persistent and widely distributed across the genome and are frequently linked...
-
Physical, Chemical, and Microbiological Attributes as Discriminators of Coffee-Growing and Forest Sites in Different Soils in the Brazilian Atlantic Forest Biome
PurposeThe aim of this study was to determine the effect of different soil textures and land use (natural and agricultural) on microbiological...
-
Seasonal shift in trophic status induced by bacterial metabolic activity in tropical mangrove-dominated estuaries of Southwest India
Mangroves are highly productive ecosystems that supply carbon and nutrients to the coastal food web from autochthonous and allochthonous sources. The...
-
Dihydroorotate dehydrogenase inhibition reveals metabolic vulnerability in chronic myeloid leukemia
The development of different generations of BCR-ABL1 tyrosine kinase inhibitors (TKIs) has led to the high overall survival of chronic myeloid...
