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Chitosan functionalized Mn3O4 nanoparticles counteracts ulcerative colitis in mice through modulation of cellular redox state
Recent findings suggest a key role for reactive oxygen species (ROS) in the pathogenesis and progression of ulcerative colitis (UC). Several studies...
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Cellular Mechanisms of the Formation of Plant Adaptive Responses to High Temperatures
Extreme temperatures, whose effect on plants has been especially enhanced in recent decades, are among the most dangerous stress abiotic factors. The...
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Radioresistance or/and radiosensitivity of head and neck squamous cell carcinoma: biological angle
ObjectiveThis narrative review aimed to compile and summarize clinically relevant literature in radiation therapy and to discuss the potential in...
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Clinical targeting of the cerebral oxygen cascade to improve brain oxygenation in patients with hypoxic–ischaemic brain injury after cardiac arrest
The cerebral oxygen cascade includes three key stages: (a) convective oxygen delivery representing the bulk flow of oxygen to the cerebral vascular...
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Different types of cell death and their shift in sha** disease
Cell death is the irreversible stop of life. It is also the basic physiological process of all organisms which involved in the embryonic development,...
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Ag/AgCl Decorated Ionic Liquid@Tantalum Pentoxide Nanostructures: Fabrication, Photocatalytic Activity, and Cytotoxicity Effects Against Human Brain Tumor Cells
Environmental contaminants have become a major concern for human beings due to their adverse effects on drinking water quality. Heterogeneous...
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Genome-scale metabolic network of human carotid plaque reveals the pivotal role of glutamine/glutamate metabolism in macrophage modulating plaque inflammation and vulnerability
BackgroundMetabolism is increasingly recognized as a key regulator of the function and phenotype of the primary cellular constituents of the...
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Crop Physiology and Biotechnology
Plant physiology has significantly contributed to the feeding of human beings. Applications of our knowledge of key concepts and processes in plant...
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Metabolic profile of mesenchymal stromal cells and macrophages in the presence of polyethylene particles in a 3D model
BackgroundContinuous cross talk between MSCs and macrophages is integral to acute and chronic inflammation resulting from contaminated polyethylene...
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Plant System Biology
Modern systems biology emerged owing to the necessity to translate the massive amounts of data produced by genome-scale investigations into...
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Scientific Landscape of Oxidative Stress in Stroke: From a Bibliometric Analysis to an in-Depth Review
Stroke is an acute cerebrovascular disease resulting from either obstruction or rupture of a blood vessel in the brain. Oxidative stress (OS),...
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Energy Demand of the Human Baby Brain
Have you ever considered the reason why I am? We know that the substance that allows us to be ourselves is only one. The brain is the substance that...
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A network pharmacology approach to decipher the mechanism of total flavonoids from Dracocephalum Moldavica L. in the treatment of cardiovascular diseases
Aim of the studyCardiovascular disease (CVD) seriously endangers human health and is characterized by high mortality and disability. The...
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A small protein coded within the mitochondrial canonical gene nd4 regulates mitochondrial bioenergetics
BackgroundMitochondria have a central role in cellular functions, aging, and in certain diseases. They possess their own genome, a vestige of their...
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Chemiosmosis and Modern Symbioses
Why should individuals of two different species cooperate? In evolutionary terms, cooperation usually involves costs and thus is not an automatic...
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Axonal energy metabolism, and the effects in aging and neurodegenerative diseases
Human studies consistently identify bioenergetic maladaptations in brains upon aging and neurodegenerative disorders of aging (NDAs), such as...
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Dichloroacetate as a metabolic modulator of heart mitochondrial proteome under conditions of reduced oxygen utilization
Myocardial compensatory mechanisms stimulated by reduced oxygen utilization caused by streptozotocin-induced diabetes mellitus (DM) and treated with...
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The Role of Sestrins in the Regulation of the Cellular Response to Stress
AbstractThis review is devoted to the analysis of proteins of the sestrin family and their role in the response of cells to stress. The paper...
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Chemiosmosis and the Origin of Eukaryotes
Because their energy-converting membranes are on the outside of the cell, surface-to-volume constraints limit the size and complexity of prokaryotic...