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Ectopic mineralization-inspired cell membrane-based matrix vesicle analogs for in-depth remineralization of dentinal tubules for treating dentin hypersensitivity
The invasion of etched dentinal tubules (DTs) by external substances induces dentin hypersensitivity (DH). The deep and compact occlusion of DTs is...
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Establishment and evaluation of a nomogram prediction model for the risk of vascular calcification in stage 5 chronic kidney disease patients
Vascular calcification (VC) is a common complication of chronic kidney disease (CKD) that has a detrimental effect on patients' survival and...
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Calcification of Joints and Arteries (CALJA) Is a Rare Cause of Arthritis and Lower Limb Ischemia: Case Report and Literature Review
Calcification of Joints and Arteries (CALJA) is a rare disease that leads to chronic arthritis and lower limb claudication due to hydroxyapatite...
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AMPK-mediated autophagy is involved in the protective effect of canagliflozin in the vitamin D3 plus nicotine calcification model in rats
Vascular calcification (VC) is a major risk factor for cardiovascular events. A mutual interplay between inflammation, oxidative stress, apoptosis,...
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Vector potential dual effect of promoting the proliferation of chondrocytes and inhibiting the calcification process in the articular cartilage
OA commonly affects the articular cartilage of the tibia, and its calcification worsens its advancement and its prevalence has recently increased....
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The role of miR-433-3p in vascular calcification in type 2 diabetic patients: targeting WNT/β-Catenin and RANKL/RANK/OPG signaling pathways
BackgroundVascular calcification (VC) is a major predictor of cardiovascular diseases that represent the principal cause of mortality among type-2...
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Transcription factor 21 accelerates vascular calcification in mice by activating the IL-6/STAT3 signaling pathway and the interplay between VSMCs and ECs
Vascular calcification is caused by the deposition of calcium salts in the intimal or tunica media layer of the aorta, which increases the risk of...
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Spinal ectopic recurrence of craniopharyngioma in a pediatric patient
Craniopharyngiomas are rare, benign lesions that can be treated with surgery, radiation therapy, or a combination of these modalities. They have a...
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Ectopic calcification and formation of mineralo-organic particles in arteries of diabetic subjects
Vascular calcification occurs in various diseases including atherosclerosis, chronic kidney disease and type 2 diabetes but the mechanism underlying...
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Ectopic invasive ACTH-secreting pituitary adenoma mimicking chordoma: a case report and literature review
BackgroundEctopic pituitary adenoma (EPA) is defined as a special type of pituitary adenoma that originates outside of the sellar region, is extra-...
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Massive calcification around large joints in a patient subsequently diagnosed with adult-onset hypophosphatasia
We report a 64-year-old Japanese woman with a history of progressive loss of motor function and painful swelling of large joints. At the age of 54,...
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Robotic resection of ectopic mediastinal parathyroid adenoma with intraoperative parathyroid hormone monitoring: a case report
BackgroundPrimary hyperparathyroidism is a disease caused by the secretion of excess parathyroid hormone (PTH) owing to the enlargement of the...
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Extra-coronary Calcification and Cardiovascular Events: What Do We Know and Where Are We Heading?
Purpose of ReviewThe coronary artery calcium score is a guideline-endorsed aid for further risk stratification in the primary prevention of...
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Beneficial effect of the short-chain fatty acid propionate on vascular calcification through intestinal microbiota remodelling
BackgroundVascular calcification is a major cause of the high morbidity and mortality of cardiovascular diseases and is closely associated with the...
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Vascular Calcification and Calciphylaxis in Peritoneal Dialysis Patients
Cardiovascular disease is the leading cause of death in end-stage renal disease (ESRD) patients, including hemodialysis and peritoneal dialysis (PD)....
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Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox
Adipocyte differentiation of bone marrow mesenchymal stem/stromal cells (BMSCs) instead of osteoblast formation contributes to age- and...
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Citric acid-based bicarbonate dialysate attenuates aortic arch calcification in maintenance hemodialysis patients: a retrospective observational study
BackgroundProgression of aortic calcification is associated with all-cause and cardiovascular mortality in hemodialysis patients. Blood calciprotein...
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MFG-E8 promotes osteogenic transdifferentiation of smooth muscle cells and vascular calcification by regulating TGF-β1 signaling
Vascular calcification occurs in arterial aging, atherosclerosis, diabetes mellitus, and chronic kidney disease. Transforming growth factor-β1...
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Chondrocyte-derived exosomes promote cartilage calcification in temporomandibular joint osteoarthritis
BackgroundsAbnormal cartilage calcification is one of the pathological changes of temporomandibular joint (TMJ) osteoarthritis (OA). Recent studies...
