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Sexual dimorphism in shape and size of the neurocranium
Sex identification is a primary step in forensic analysis of skeletal remains. The accuracy of sex estimation methods greatly depends on the sexual...
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Sexual dimorphism in colorectal cancer: molecular mechanisms and treatment strategies
IntroductionSexual dimorphism significantly influences cancer incidence and prognosis. Notably, females exhibit a lower risk and favorable prognosis...
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Sexual Dimorphism in the Ontogeny of the Black Forest–Steppe Adder (Pelias berus nikolskii (Vedmederja, Grubant et Rudaeva 1986), Serpentes, Viperidae) from Voronezh Oblast, Based on Traditional Measurements
AbstractMales and females of the black forest–steppe adder ( Pelias berus nikolskii ) inhabiting Voronezh oblast, apart from differences in tail...
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Selfit—Accounting for Sexual Dimorphism in Personalized Motor Skills Learning
The development and the upkeep of psychomotor skills are fundamental for performing safely and efficiently daily life, professional, or leisure...
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Sexual dimorphism in the social behaviour of Cntnap2-null mice correlates with disrupted synaptic connectivity and increased microglial activity in the anterior cingulate cortex
A biological understanding of the apparent sex bias in autism is lacking. Here we have identified Cntnap2 KO mice as a model system to help better...
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Intrinsic aerobic capacity modulates Alzheimer’s disease pathological hallmarks, brain mitochondrial function and proteome during aging
Low aerobic capacity is strongly associated with all-cause mortality and risk for Alzheimer’s disease (AD). Individuals with early dementia and AD...
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White matter brain age as a biomarker of cerebrovascular burden in the ageing brain
As the brain ages, it almost invariably accumulates vascular pathology, which differentially affects the cerebral white matter. A rich body of...
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Hepatic sexual dimorphism — implications for non-alcoholic fatty liver disease
The liver is often thought of as a single functional unit, but both its structural and functional architecture make it highly multivalent and...
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Profiling the neuroimmune cascade in 3xTg-AD mice exposed to successive mild traumatic brain injuries
Repetitive mild traumatic brain injuries (rmTBI) sustained within a window of vulnerability can result in long term cognitive deficits, depression,...
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Identification of female-enriched and disease-associated microglia (FDAMic) contributes to sexual dimorphism in late-onset Alzheimer’s disease
BackgroundLate-onset Alzheimer’s disease (LOAD) is the most common form of dementia; it disproportionally affects women in terms of both incidence...
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A More Female-Characterized Resting-State Brain: Graph Similarity Analyses of Sex Influence on the Human Brain Intrinsic Functional Network
It remains unclear whether human species exhibits sexual dimorphism in brain activities, and how the dimorphisms associated with sex-characterized...
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Loss of Epitranscriptomic Modification N6-Methyladenosine (m6A) Reader YTHDF1 Exacerbates Ischemic Brain Injury in a Sexually Dimorphic Manner
N 6 -Methyladenosine (m 6 A) is a neuronal-enriched, reversible post-transcriptional modification that regulates RNA metabolism. The m 6 A-modified RNAs...
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Pomc Plays an Important Role in Sexual Size Dimorphism in Tilapia
Sexual dimorphism is common across the animal kingdom. Knowledge of the mechanisms of sexual size dimorphism is limited although it is important in...
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Brains vs Brawn: Relative brain size is sexually dimorphic amongst weapon-bearing ruminants
AbstractHere, we investigate the relationship between relative brain size and sexual weapons in ruminants. In most cases, sexual weaponry is heavily...
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Sex-Dimorphic Kidney-Brain Connectivity Map of Mice
The kidneys are essential organs that help maintain homeostasis, and their function is regulated by the neural system. Despite the anatomical...
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Sexual dimorphism in mitochondrial dysfunction and diabetes mellitus: evidence from a population-based cohort study
BackgroundPathophysiological mechanisms underlying sex-based differences in diabetes remain poorly understood. Mitochondrial metabolite methylmalonic...
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Analysis of androgen receptor expression and activity in the mouse brain
Androgen deprivation therapy (ADT) is the core treatment for advanced prostate cancer (PCa), with a proven survival benefit. ADT lowers circulating...
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