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Impact of Appropriate Use Criteria for Cross-Sectional Imaging on Medical Decision-Making in Patients with Conotruncal Defects
Associations between Appropriate Use Criteria (AUC) ratings and medical decision-making in congenital heart disease are not well-established. We...
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Complement Inhibition Reduces Early Erythrolysis, Attenuates Brain Injury, Hydrocephalus, and Iron Accumulation after Intraventricular Hemorrhage in Aged Rats
Blood components released by erythrolysis play an important role in secondary brain injury and posthemorrhagic hydrocephalus (PHH) after...
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Cardiopulmonary Exercise Testing in Children and Adolescents with Repaired Tetralogy of Fallot: Mechanisms of Exercise Intolerance and Clinical Implications
By comparison with adults, cardiopulmonary exercise testing in children with Tetralogy of Fallot is limited, and its clinical application less...
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Adaptive Functioning and Sleep Quality: Associations in Young Children with Congenital Heart Disease
Congenital heart disease (CHD) is one of today’s leading birth anomalies. Children with CHD are at risk for adaptive functioning challenges. Sleep...
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Five-Year Outcomes of Coarctoplasty with Stents in the Pediatric Population: Results from a Retrospective Single-Center Cohort with Centrally Adjudicated Outcomes
Transcatheter stent implantation is a widely performed procedure for treating native coarctation of the aorta (CoA) in pediatric patients. However,...
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HDAC9 Deficiency Upregulates cGMP-dependent Kinase II to Mitigate Neuronal Apoptosis in Ischemic Stroke
Histone deacetylase 9 (HDAC9) is implicated in ischemic stroke by genome-wide association studies. We conducted a series of experiments using a mouse...
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Diagnostic Value of 99mTc-MIBI Myocardial Perfusion Imaging in Detecting Myocardial Ischemia of Children with Kawasaki Disease and Coronary Artery Lesions
Pediatric patients with coronary artery lesions (CALs) after Kawasaki disease (KD) may be complicated with myocardial ischemia. Although previous...
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Prognostic value of tumor regression grade (TRG) after oncological gastrectomy for gastric cancer
PurposePerioperative chemotherapy combined with surgical resection represent the gold standard in the treatment of locally advanced gastric cancer....
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Robotic surgery versus conventional laparoscopy in sigmoid colectomy for diverticular disease-a comparison of operative trauma and cost-effectiveness: retrospective, single-center analysis
PurposeRobotic assisted surgery is an alternative, fast evolving technique for performing colorectal surgery. The primary aim of this single center...
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Recognition of Patient Gender: A Machine Learning Preliminary Analysis Using Heart Sounds from Children and Adolescents
Research has shown that X-rays and fundus images can classify gender, age group, and race, raising concerns about bias and fairness in medical AI...
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The relation of recurrent laryngeal nerve to inferior thyroid artery and extralaryngeal nerve branching may increase the risk of vocal cord paralysis in thyroidectomy
PurposeThe anatomical variations of the recurrent laryngeal nerve (RLN) are common during thyroidectomy. We aimed to evaluate the risk of RLN...
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Late presentation of congenital heart diseases in low- and middle-income countries: impact on outcomes
In low- and middle-income countries (LMICs), the delayed detection and presentation of congenital heart defects (CHDs) present significant hurdles,...
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Long-Term Outcomes of Surgical Repair of Supracardiac Total Anomalous Pulmonary Venous Connection
The conventional surgery (CS) of supracardiac total anomalous pulmonary venous connection (TAPVC) is not always effective particularly in the setting...
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Reducing Adverse Events Associated with Pediatric Cardiac Catheterization: A Quality Improvement Project Focusing on Decreasing Catheterization-Associated Blood Transfusions
The objective of this study is to describe interventions and outcomes of a quality improvement (QI) project to reduce red blood cell transfusion...
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Establishing Optimal Control Cohorts for Phase 1 Trials: Retrospective Analysis of Clinical and Biological Outcomes in Neonates and Infants Undergoing Two-Ventricle Repair
Phase 1 trials are primarily conducted to evaluate the safety and feasibility of new interventions, usually without recruiting control patients. This...
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Clinical Course of Residual Ventricular Septal Defects After Congenital Heart Disease Repair
The clinical course of residual ventricular septal defects after congenital heart disease repair is not completely elucidated in the medical...
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A Prospective Randomized Controlled Trial Using Virtual Reality in Pediatric Pre-intervention Echocardiograms to Decrease Child Anxiety and Fear
Virtual reality (VR) as a distraction tool decreases anxiety and fear in children undergoing procedures, but its use has not been studied during...
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Integrating platelet reactivity in the age, creatinine and ejection fraction score to predict clinical outcomes following percutaneous coronary intervention in patients with chronic coronary syndrome: the PR-ACEF score
To evaluate if integrating platelet reactivity (PR) evaluation in the original age, creatinine and ejection fraction (ACEF) score could improve the...
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The introduction of a 42 + 4 h work week for surgical residents in Switzerland – a stakeholder analysis
BackgroundThe Swiss national union of residents and attendings (VSAO) has voiced its desire for a transition from the current 48 h work week to a...
