Search
Search Results
-
Short-term OS as a surrogate endpoint for 5-year OS in nasopharyngeal carcinoma in non-endemic area
PurposeTo address this evidence gap and validate short-term OS at less than 5 years as a reliable surrogate endpoint for 5-year OS.
Methods ...
-
Survival of advanced/recurrent gastrointestinal stromal tumors treated with tyrosine kinase inhibitors in Taiwan: a nationwide registry study
BackgroundMost gastrointestinal stromal tumors (GISTs) harbor c-KIT or PDGFRA mutations. Administration of tyrosine kinase inhibitors (TKIs) has...
-
Impact of baseline body composition on prognostic outcomes in urological malignancies treated with immunotherapy: a pooled analysis of 10 retrospective studies
ObjectiveNumerous epidemiological investigations have explored the impact of body composition on the effectiveness of immune checkpoint inhibitors...
-
Stereotactic body radiation therapy for multiple lung cancers in a patient with six primary cancers: a case report
BackgroundSurgery is the standard care for patients with early-stage lung cancer, and stereotactic body radiation therapy is an option for those who...
-
Circ_0000069 promotes the development of hepatocellular carcinoma by regulating CCL25
BackgroundHepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths globally, influenced by aberrant circRNA expression....
-
Chemoradiotherapy versus radiotherapy in high risk salivary gland cancer
ObjectiveThe aim of this study was to investigate the potential survival benefits associated with chemoradiotherapy (CRT) as opposed to radiotherapy...
-
A phase 3, randomized, double-blind, multicenter, placebo-controlled study of S-588410, a five-peptide cancer vaccine as an adjuvant therapy after curative resection in patients with esophageal squamous cell carcinoma
BackgroundS-588410, a cancer peptide vaccine (CPV), comprises five HLA-A*24:02-restricted peptides from five cancer-testis antigens. In a phase 2...
-
A double CYP27A1 gene mutation in spinal cerebrotendinous xanthomatosis in a patient presenting with spastic gait: a case report
BackgroundCerebrotendinous xanthomatosis (CTX, OMIM #213700) is a rare inherited metabolic disease caused by the mutation in the CYP27A1 gene....
-
Outcome of Reconstruction with Irradiated Tumour Bone in Paediatric Malignant Bone Tumours
Reconstruction of a paediatric bone tumour after wide excision is challenging. Autologous sterilized tumour bone provides a perfect fit, avoids wear...
-
Case Series of Angiomatoid Fibrous Histiocytoma (AFH)—A Clinico-Radiological and Pathological Conundrum
Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor, common in children and young adults, often misdiagnosed as either reactive or...
-
Central nervous system involvement in chronic lymphocytic leukemia: a case report and review of literature
BackgroundCentral nervous system involvement in chronic lymphocytic leukemia rarely occurs, and there is no standard therapy for central nervous...
-
Successful intrahepatic cholangiocarcinoma conversion surgery after administration of fibroblast growth factor receptor inhibitor
We describe a case of a 47-year-old male patient with initially unresectable intrahepatic cholangiocarcinoma of the right liver lobe with tumor...
-
The black box of the relationship between breast cancer patients and accompanying patients: the accompanied patients’ point of view
BackgroundThe PAROLE-Onco program was introduced in the province of Quebec, Canada in 2019. It integrates accompanying patients (APs), i.e., people...
-
Long-Term Effects of Oral Nutritional Supplements After Gastrectomy for Gastric Cancer: A Survival Analysis from a Multicenter, Open-Label, Randomized Controlled Trial
BackgroundWeight loss (WL) after gastrectomy for gastric cancer is associated with both decreased compliance with adjuvant chemotherapy and impaired...
-
Mitochondrial DNA Copy Number as a Biomarker for Guiding Adjuvant Chemotherapy in Stages II and III Colorectal Cancer Patients with Mismatch Repair Deficiency: Seeking Benefits and Avoiding Harms
BackgroundColorectal cancer (CRC) patients with mismatch repair-deficient/microsatellite instability-high (dMMR/MSI-H) status are conventionally...
-
Operative Therapie des Vulva- und Vaginalkarzinoms
Surgical treatment of cancer of the vulva and vagina is an important part of therapy. Complete removal of the tumour with an adequate safety margin...
-
Associations between modifiable risk factors and hepatocellular carcinoma: a trans-ancestry Mendelian randomization study
BackgroundPotentially modifiable risk factors for hepatocellular carcinoma (HCC) have been investigated in observational epidemiology studies in East...
-
Factsheet: Epidemiologie von Krebserkrankungen der Vulva und Vagina in Deutschland
Between 2017 and 2020, an average of 3650 women were diagnosed with vulvar or vaginal cancer each year. In the 3 years from 2020–2022 another 5400...
