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Sodium-Glucose Cotransporter 2 Inhibitors During Cancer Therapy: Benefits, Risks, and Ongoing Clinical Trials
Purpose of reviewThe goal of this paper is to summarize the data pertaining to the use of sodium-glucose cotransporter-2 inhibitors (SGLT-2i) for the...
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De-novo ATR-16 syndrome associated with inherited hemoglobin Evanston causing HbH phenotype: a rare occurrence
Abnormality of three α-globin genes, either deletion or point mutation results in symptomatic Hemoglobin H (HbH) phenotype. Most of such cases of...
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Fasting in combination with the cocktail Sorafenib:Metformin blunts cellular plasticity and promotes liver cancer cell death via poly-metabolic exhaustion
PurposeDual-Interventions targeting glucose and oxidative metabolism are receiving increasing attention in cancer therapy. Sorafenib (S) and...
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ESRP1-mediated biogenesis of circPTPN12 inhibits hepatocellular carcinoma progression by PDLIM2/ NF-κB pathway
BackgroundEmerging evidence indicates the pivotal involvement of circular RNAs (circRNAs) in cancer initiation and progression. Understanding the...
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Exploration of helpful elements contributing to engage in physical activity in patients with cancer
PurposeAlthough there are many reported benefits of physical activity for patients with cancer (e.g., improving quality of life), many patients with...
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N6-methyladenosine modification of circMARK2 enhances cytoplasmic export and stabilizes LIN28B, contributing to the progression of Wilms tumor
BackgroundThe potential involvement of circular RNAs (circRNAs) and N 6 -methyladenosine (m 6 A) modification in the progression of Wilms tumor (WT) has...
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Survival of advanced/recurrent gastrointestinal stromal tumors treated with tyrosine kinase inhibitors in Taiwan: a nationwide registry study
BackgroundMost gastrointestinal stromal tumors (GISTs) harbor c-KIT or PDGFRA mutations. Administration of tyrosine kinase inhibitors (TKIs) has...
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Sperm DNA fragmentation and infertility: a narrative review
PurposeThe purpose of this narrative review is to provide a practical understanding of sperm DNA fragmentation (SDF) in the management of male...
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Anti-cancer potential of casein and its derivatives: novel strategies for cancer treatment
Cancer is one of the leading causes of death worldwide, with over 10 million fatalities annually. While tumors can be surgically removed and treated...
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Efficacy of lengthening right renal veins using accompanying gonadal veins in living donor kidney transplantation
BackgroundShort harvested right renal veins (RV) are quite common in living donor kidney transplantation (KT). This technical difficulty might...
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Circ_0000069 promotes the development of hepatocellular carcinoma by regulating CCL25
BackgroundHepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths globally, influenced by aberrant circRNA expression....
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Survival after thermal ablation versus wedge resection for stage I non-small cell lung cancer < 1 cm and 1 to 2 cm: evidence from the US SEER database
BackgroundThis study compared the survival outcomes after thermal ablation versus wedge resection in patients with stage I non-small cell lung cancer...
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Genetic and clinical characteristics of acute B-cell lymphoblastic leukemia with MEF2D fusions and report of two novel MEF2D rearrangements
The MEF2D rearrangement is a recurrent chromosomal abnormality detected in approximately 2.4–5.3% of patients with acute B-cell lymphoblastic...
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Selective iliofemoral stent placement for complex pediatric cases: a decade of institutional experience
BackgroundPediatric iliofemoral venous thromboembolism that is resistant to conventional treatments poses significant management challenges. Stent...
