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Current Topics Regarding the Function of the Medial Temporal Lobe Memory System
The first clear insight that the medial temporal lobe of the human brain was in fact a system of anatomically connected structures that were...
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Muscle MRI as a biomarker of disease activity and progression in myotonic dystrophy type 1: a longitudinal study
IntroductionMyotonic dystrophy type 1 (DM1) is an autosomal dominant disease characterized by myotonia and progressive muscular weakness and atrophy....
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The risks for major psychiatric disorders in the siblings of probands with major depressive disorder
Using a case-controlled study including siblings of major depression (MD) and control probands, born 1970–1990 and followed through 2018, we sought...
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The brachioradialis longus: an unreported accessory form of the brachioradialis muscle
The brachioradialis muscle (BR) belongs to the lateral forearm muscle. Typically, the radial nerve innervates it. BR morphological variability, such...
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Modulating social learning-induced evaluation updating during human sleep
People often change their evaluations upon learning about their peers’ evaluations, i.e., social learning. Given sleep’s vital role in consolidating...
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Phenotypic and mutational spectrum of 17 Chinese patients with Menkes Disease
BackgroundMenkes Disease (MD) is a fatal X-linked recessive disorder caused by mutations in the ATP7A gene. Severe cases typically die before the age...
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Aticaprant, a kappa opioid receptor antagonist, and the recovered ‘interest and pleasure’ in the concept of major depressive disorder
Lack of positive mood and anhedonia probably are the most specific depressive symptoms. Anhedonia is a multifaceted concept: the clinical language...
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Predictors of changes in marijuana consumption in Germany during the covid-19 pandemic
During the Covid-19 pandemic Germany experienced its first increase in the proportion of heavy cannabis users since 1995. With the expected...
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What Chemsex does to the brain - neural correlates (ERP) regarding decision making, impulsivity and hypersexuality
Chemsex describes the use of specific substances (methamphetamine, GHB/GBL, mephedrone, ketamine) which initiate or enhance sexual experiences and is...
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Guideline “Parkinson’s disease” of the German Society of Neurology (Deutsche Gesellschaft für Neurologie): concepts of care
IntroductionIn 2023, the German Society of Neurology published a new guideline on Parkinson’s disease. An important section dealt with PD care...
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Clinical application of plasma P-tau217 to assess eligibility for amyloid-lowering immunotherapy in memory clinic patients with early Alzheimer’s disease
BackgroundWith the approval of disease-modifying treatments (DMTs) for early Alzheimer’s disease (AD), there is an increased need for efficient and...
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Frontal-striatal glucose metabolism and fatigue in patients with multiple sclerosis, long COVID, and COVID-19 recovered controls
This study compared brain glucose metabolism using FDG-PET in the caudate nucleus, putamen, globus pallidus, thalamus, and dorsolateral prefrontal...
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Increased anti-correlation between the left dorsolateral prefrontal cortex and the default mode network following Stanford Neuromodulation Therapy (SNT): analysis of a double-blinded, randomized, sham-controlled trial
SNT is a high-dose accelerated intermittent theta-burst stimulation (iTBS) protocol coupled with functional-connectivity-guided targeting that is an...
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The ethics of artificial intelligence systems in healthcare and medicine: from a local to a global perspective, and back
Artificial intelligence systems (ai-systems) (e.g. machine learning, generative artificial intelligence), in healthcare and medicine, have been...
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The Association Between Adverse Childhood Experiences and Sleep in Children with Autism Spectrum Disorder
Children with autism spectrum disorder are at higher risk for adverse childhood experiences (ACEs). They are also more vulnerable to sleep problems...
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Simulated complexes formed from a set of postsynaptic proteins suggest a localised effect of a hypomorphic Shank mutation
BackgroundThe postsynaptic density is an elaborate protein network beneath the postsynaptic membrane involved in the molecular processes underlying...
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Thalamocortical functional connectivity and rapid antidepressant and antisuicidal effects of low-dose ketamine infusion among patients with treatment-resistant depression
Previous studies have shown an association between the thalamocortical dysconnectivity and treatment-resistant depression (TRD). Whether a single...
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The impact of premature birth on auditory-visual processes in very preterm schoolchildren
Interactions between stimuli from different sensory modalities and their integration are central to daily life, contributing to improved perception....
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Which learning techniques supported by cognitive research do students use at secondary school? Prevalence and associations with students’ beliefs and achievement
Research in cognitive science has highlighted the effectiveness of several learning techniques, and a number of studies have analyzed their...
